Abstract: Nucleic acid molecules are described encoding a starch granule-bound protein as well as methods and recombinant DNA molecules for the production of transgenic plant cells and plants synthesizing a modified starch with modified viscosity properties and a modified phosphate content. Moreover, the plant cells and plants resulting from those methods as well as the starch obtainable therefrom are described.
Abstract: The invention relates to formulations containing at least one nitrogen-free polysiloxane compound, at least one polyamino polysiloxane and/or polyammonium polysiloxane compound, and/or at least one amino polysiloxane and/or ammonium polysiloxane compound, and an optional silicone-free cationic surfactant, a coacervate phase-forming agent, and carrier substances. Also disclosed are a method for the production of the inventive formulations and the use thereof for treating natural and synthetic fibrous materials.
Type:
Application
Filed:
October 31, 2003
Publication date:
July 27, 2006
Applicant:
GE Bayer Silicones GmbH & Co. KG
Inventors:
Horst Lange, Christopher Roos, Roland Wagner, Martin Kropfgangs, Andrew Graydon, Richard Hartshorn, Jean-Pol Boutique, Patrick Delplanque, James Johnston
Abstract: Method for separating blood plasma particles from a blood plasma suspension in a self-discharging centrifuge having two or more discharge slits and axially stacked baffle plates, in which the blood plasma particles are separated from the liquid phase by centrifuging and removal of the liquid phase, suctioning off liquid remaining in the drum after separation of the blood plasma particles and discharging the sediment of solid blood plasma particles from the drum by centrifugal force into a collecting container underneath the drum, the drum and the blood plasma sediment being cooled during one or more of the process steps.
Type:
Grant
Filed:
July 30, 2002
Date of Patent:
July 25, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Jürgen Scholz, Markus Longerich, Ernst-Ulrich Himmen, Ulrich Esser, Rajesh Sharma, Anshuman V. Patwardhan
Abstract: The present invention relates to polymer blends containing a component selected from the group poly(ester)carbonates, graft polymers or mixtures thereof, polyalkylene naphthalate as the second component optionally together with a further component selected from the group of vinyl (co)polymers, polyalkylene terephthalates or mixtures thereof, wherein mixtures of polycarbonate, polyalkylene naphthalate and optionally polyalkylene terephthalate contain no tetrafluoroethylene polymer.
Type:
Grant
Filed:
June 10, 2004
Date of Patent:
July 25, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Holger Warth, Dieter Wittmann, Heinrich Alberts
Abstract: The invention provides a human GPR40 which is associated with the hematological diseases, disorders of the peripheral and central nervous system, gastrointestinal diseases, respiratory diseases, metabolic disease, cancer, cardiovascular diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, disorders of the peripheral and central nervous system, gastrointestinal diseases, respiratory diseases, metabolic disease, cancer, cardiovascular diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR40 as well as pharmaceutical compositions comprising such compounds.
Type:
Application
Filed:
February 4, 2004
Publication date:
July 20, 2006
Applicant:
Bayer Healthcare AG
Inventors:
Stefan Golz, Ulf Bruggemeier, Holger Summer
Abstract: The invention provides a human GPR14 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, urological diseases, endocrinological diseases and cancer. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, urological diseases, endocrinological diseases and cancer. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR14 as well as pharmaceutical compositions comprising such compounds.
Type:
Application
Filed:
October 15, 2003
Publication date:
July 20, 2006
Applicant:
Bayer Healthcare AG
Inventors:
Stefan Golz, Ulf Bruggemeier, Andreas Geerts
Abstract: The present invention provides a multilayer bandage, comprising a webbing for contacting a wound and a first membrane that comprises at least one water-insoluble polymer and is water-impervious. The present invention further provides methods for making the multilayer bandage, methods of using the multilayer bandage for accelerated wound healing, and kits comprising compositions of the present invention.
Type:
Application
Filed:
December 30, 2005
Publication date:
July 20, 2006
Applicant:
Bayer Innovation GmbH
Inventors:
Axel Thierauf, Iwer Baecker, Andreas Haisch
Abstract: The invention provides a human HM74a which is associated with the disorders of the peripheral and central nervous system, cardiovascular diseases, hematological diseases, cancer, inflammation, urological diseases, respiratory diseases and gastroen-terological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the peripheral and central nervous system, cardiovascular diseases, hematological diseases, cancer, inflammation, uro-logical diseases, respiratory diseases and gastroenterological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of HM74a as well as pharmaceutical compositions comprising such compounds.
Type:
Application
Filed:
February 5, 2004
Publication date:
July 20, 2006
Applicant:
Bayer Healthcare AG
Inventors:
Stefan Golz, Ulf Bruggemeier, Holger Summer
Abstract: The invention relates to a method for the automatic design of experiments, having the following steps: inputting a similarity measure of two experiments, inputting a weighting measure for an individual experiment, determining a quality measure based on the similarity measure and the weighting measure, finding a number of experiments where the quality measure assumes an extreme value.
Type:
Grant
Filed:
February 25, 2003
Date of Patent:
July 18, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Rolf Burghaus, Georg Mogk, Thomas Mrziglod, Peter Hübl
Abstract: A process for producing bisphenol A is disclosed. The process entails a) reacting phenol with acetone in the presence of an acidic catalyst to form a reaction mixture that includes bisphenol A and water, and b) removing water from the reaction mixture by distillation in a column to obtain a bottom product, and c) separating bisphenol-A/phenol adduct from the reaction mixture by crystallization and filtration. The bottom temperature of the column is 100 to 150° C., the overhead temperature of the column is 20 to 80° C., the absolute pressure is 50 to 300 mbar at the head of the column and 100 to 300 mbar at the bottom of the column, and wherein said (c) is carried out before or after said (b).
Type:
Grant
Filed:
January 26, 2005
Date of Patent:
July 18, 2006
Assignee:
Bayer Materialscience AG
Inventors:
Rainer Neumann, Ulrich Blaschke, Stefan Westernacher
Abstract: This application relates to pyridine derivatives having the general structure in which the several variables are as defined in the specification and claims, and to a process for preparing these compounds, a pharmacutical composition containing such compounds, and a method for using these materials for treatment of stable and unstable angina pectoris and atrial fibrillation.
Type:
Grant
Filed:
March 19, 2002
Date of Patent:
July 18, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch, Mitsuyuki Shimada
Abstract: The present invention relates to a process for preparing novel, monodisperse ion exchangers having chelating functional groups, and their use for adsorbing metal compounds, in particular, heavy metal compounds and noble metal compounds, and also for extracting alkaline-earth metals from saline solutions from alkali metal chloride electrolysis.
Type:
Grant
Filed:
October 17, 2003
Date of Patent:
July 18, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Reinhold Klipper, Werner Strüver, Ulrich Schnegg, Bruno Hees, Bernhard Lehmann, Holger Lütjens
Abstract: A dielectric capacitor having self healing properties is disclosed. The capacitor includes a film made of an amorphous aromatic copolycarbonate having a weight average molecular weight of at least 10,000 and a glass transition temperature of at least 160° C. In a preferred embodiment the copolycarbonate includes structural units derived from bisphenol TMC. Also disclosed is a process for making the film.
Type:
Grant
Filed:
January 15, 2003
Date of Patent:
July 18, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hans-Leo Weber, Klaus Meyer, Peter Bier
Abstract: The present invention relates to a process for preparing compounds of the formula (I) where R is H or F, by (a) reacting a compound of the formula (II) where X is halogen, mesylate or tosylate with a thiocyanate, (b) reacting the resultant product with H2S or one of its salts to give a dithiocarbamate, and (c) reacting the dithiocarbamate with acetaldehyde, chloroacetaldehyde or an acetal thereof, and further relates to intermediates used in this process.
Abstract: Reagents which regulate human prostasin-like enzyme activity and reagents which bind to human prostasin-like enzyme gene products can be used to regulate human prostasin-like enzyme activity. Such regulation is particularly useful for treating metastasis of malignant cells, tumor angiogenesis, inflammation, atherosclerosis, neurodegenerative diseases, and pathogenic infections.
Abstract: 2-Alkyl-3-aryl- or -heteroaryloxaziridines are prepared in a particularly advantageous manner by oxidizing corresponding N-alkyl-aryl- or -heteroarylaldimines with an aromatic percarboxylic acid or a salt thereof in the presence of water, a water-soluble base, and a water-miscible solvent, at temperatures below 30° C. Using this method, it is also possible to obtain novel 2-alkyl-3-aryloxaziridines.
Type:
Grant
Filed:
April 23, 2004
Date of Patent:
July 11, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Alexander Klausener, Reinhard Langer, Stephan Ratsch, Michael Dockner
Abstract: Modular device and method for carrying out experiments in parallel on process substances to develop technical methods, comprising at least a multiplicity of individual reactors which are controllable independently of one another said reactors being comprised of pressure-tight chambers having separable sample vessels, and optionally, stirring devices, heating instruments, cooling instruments, or both, a monitoring unit for monitoring or controlling at least the pressure and the temperature in the individual reactors, pressure-tight lids having independent feed lines and optionally independent discharge lines for individual process substances; a plurality of the lids being simultaneously sealable upon the rectors by a common sealing means (11).
Type:
Grant
Filed:
April 30, 2002
Date of Patent:
July 11, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Peter Jähn, Georg Wiessmeier, Bernhard Krumbach, Reinhold Rose, Thomas Siebert, Rainer Krautkrämer
Abstract: Novel ?1-pyrrolines of the formula (I) in which R1, R2, R3, A, R4 and m have the meanings given in the description, a number of processes for preparing these substances, and their use for controlling pests, and also novel intermediates and their preparation.
Type:
Grant
Filed:
September 4, 2002
Date of Patent:
July 11, 2006
Assignee:
Bayer Cropscience AG
Inventors:
Thomas Seitz, Martin Füsslein, Johannes Rudolf Jansen, Udo Kraatz, Angelika Lubos-Erdelen, legal representative, Andreas Turberg, Olaf Hansen, Christoph Erdelen, deceased
Abstract: The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
Type:
Grant
Filed:
November 17, 2003
Date of Patent:
July 11, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Erwin Bischoff, Thomas Krahn, Stephan-Nicholas Müller, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann
Abstract: A Polymer compositions that features high degree of toughness, very good processability and extremely high gloss is disclosed. The composition contains (I) a graft rubber polymer obtained by emulsion polymerization of styrene and acrylonitrile in the presence of a mixture of (A) a butadiene polymer latex having a mean particle diameter d50?250 nm, a particle size distribution width of 20 to 80 nm and a gel content of 30 to 95 wt. %, (B) a butadiene polymer latex with a mean particle diameter d50>250 to 350 nm, a particle size distribution width of 30 to 100 nm and gel content of 30 to 80 wt. %, and (C) a butadiene polymer latex (C) with a mean particle diameter d50>350 nm, a particle size distribution width of 40 to 150 nm, and a gel content of 50 to 95 wt. %. and (II) a rubber-free copolymer of styrene and acrylonitrile. At least one of (A), (B) and (C) is a product of seed polymerization.
Type:
Grant
Filed:
February 12, 2001
Date of Patent:
July 11, 2006
Assignee:
Bayer Aktiengesellschaft
Inventors:
Herbert Eichenauer, Eckhard Wenz, Heinrich Alberts, Ulrich Jansen, Hans-Erich Gasche