Patents Assigned to Bayer
  • Regulation of human CycLT2-like GPCR protein
    Publication number: 20030157541
    Abstract: Reagents which regulate human CysLT2-like GPCR protein and reagents which bind to human CysLT2-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to peripheral and central nervous system disease, asthma and cardiovascular disease.
    Type: Application
    Filed: January 23, 2003
    Publication date: August 21, 2003
    Applicant: Bayer Aktiengesellschaft
    Inventor: Yonghong Xiao
  • Double-metal cyanide catalysts for producing polyether polyols
    Patent number: 6608231
    Abstract: The invention relates to novel double metal cyanide (DMC) catalysts for the preparation of polyether polyols by polyaddition of alkylene oxides to starter compounds containing active hydrogen atoms, wherein the catalyst contains a) double metal cyanide compounds, b) organic complex ligands other than c), and c) carboxylic acid ester of polyhydric alcohols. The catalysts according to the invention have greatly increased activity in the preparation of polyether polyols.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: August 19, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Pieter Ooms, Jörg Hofmann, Pramod Gupta
  • Substituted phenyl ketoenols
    Patent number: 6608211
    Abstract: The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) in which A, B, G, X, Y, Z and W are each as defined in the description, to processes and intermediates for their preparation and to their use as pesticides and herbicides.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: August 19, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hermann Hagemann, Reiner Fischer, Christoph Erdelen, Ulrike Wachendorff-Neumann, Udo Schneider, Wolfram Andersch
  • Lancing mechanism
    Patent number: 6607543
    Abstract: A lancing mechanism for puncturing skin is provided. The lancing mechanism comprises a lance having a penetration end which is adapted to puncture skin. The penetration end of the lance is movable from a first position to a second position during a forward stroke and between the second position and the first position during a return stroke. A forcing plunger applies a force to the lance to move the lance from the first position to the second during the forward stroke. The forcing plunger is adapted to engage the lance during the forward stroke to move the penetration end of the lance from the first position to the second position and to disengage the lance when the penetration end of the lance approaches the second position. A first resilient member coupled to the lance moves the first end of the lance from the second position to the first position during the return stroke.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: August 19, 2003
    Assignee: Bayer Corporation
    Inventors: D. Glenn Purcell, Allen J. Brenneman
  • Substituted 2-aryl-1,2,4-triazine-3,5-di(thi)ones
    Patent number: 6608004
    Abstract: The invention relates to novel substituted 2-aryl-1,2,4-triazine-3,5-di(thi)ones of the general formula (I), in which Q1, Q2, R1, R2, R3, R4, R5 and R6 are each as defined in the description, and to processes for their preparation and to their use as herbicides.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: August 19, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl-Heinz Linker, Joachim Kluth, Mark Wilhelm Drewes, Peter Dahmen, Dieter Feucht, Rolf Pontzen
  • Indazoles
    Patent number: 6608049
    Abstract: The invention relates to new indazole derivatives, processes for their preparation, and their use in medicaments.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: August 19, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Woltering, Helmut Haning, Gunter Schmidt, Josef Pernerstorfer, Hilmar Bischoff, Axel Kretschmer, Verena Vöhringer, Christiane Faeste
  • Repinotan kit
    Patent number: 6605255
    Abstract: The invention relates to a kit comprising a pharmaceutical composition containing repinotan or a physiologically acceptable salt of repinotan, and a means for the determination of the concentration of repinotan or its metabolites in body fluids, and also new pharmaceutical compositions containing repinotan or a physiologically acceptable salt of repinotan, and processes for their preparation.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: August 12, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Werner Kroll, Ferdinand Rombout, Horst Weber, Maria-Luisa Rodriguez, Bernd Sennhenn, Rudolf Schohe-Loop
  • Aromatic copolyester containing active ingredients
    Patent number: 6605069
    Abstract: The invention relates to aromatic copolyesters comprising antimicrobially active substances in homogeneous distribution, processes for their preparation and their use in medical articles.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: August 12, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhard Albers, Ralf Dujardin, Heinz Pudleiner, Joachim Simon, Rita Fröde, Hartwin Hobler
  • Rapid method of determining clearance of prion protein
    Patent number: 6605445
    Abstract: Transmissible spongiform encephalopathies (TSEs) are a class of fatal, neurodegenerative diseases found in many mammalian species. Human TSEs include kuru, Creutzfeldt-Jakob disease (CJD), and fatal familial insomnia. Non-human TSEs include sheep scrapie, bovine spongiform encephalopathy (BSE), feline spongiform encephalopathy, and chronic wasting diseases in elk and mule deer. These neurodegenerative diseases are caused by prions and display characteristic amyloid plaque deposition. The only known component of the infectious prion is an abnormal, disease-causing isoform of the prion protein (PrP), called PrP scrapie (PrPSc). During a post-translational process, PrPSc is formed from the normal, cellular PrP isoform (PrPC). The scrapie isoform is less soluble, more proteinase-resistant, and more susceptible to aggregation than the wildtype protein.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 12, 2003
    Assignee: Bayer Corporation
    Inventors: Steve R. Petteway, Douglas C. Lee, Robert W. Kozak
  • Intermediates for nematicidal pyrazoles
    Patent number: 6605730
    Abstract: The invention relates to compounds of the formula R1, R2, and n have the meanings set forth in the disclosure, that are useful as intermediates for nematicidal pyrazoles.
    Type: Grant
    Filed: August 15, 2001
    Date of Patent: August 12, 2003
    Assignee: Nihon Bayer Agrochem K.K.
    Inventors: Katsuaki Wada, Takuya Gomibuchi, Yuichi Otsu, Katsuhiko Shibuya, Takahisa Abe, Wolfram Andersch, Achim Harder, Peter Lösel
  • Method for reprocessing reaction mixtures containing diaryl carbonate
    Patent number: 6605191
    Abstract: A process for the work up of a reaction mixture obtained from the preparation of diaryl carbonate by direct carbonylation of aromatic hydroxy compounds is disclosed. The process entails obtaining a reaction mixture that contains diaryl carbonate, aromatic hydroxy compound, water, base and quaternary salt, separating the mixture in a distillation apparatus having only one theoretical separation stage into a liquid phase and a gas phase and recycling the liquid phase without further work up to the reaction step of the direct carbonylation.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: August 12, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Carsten Hesse, Ursula Jansen, Johann Rechner, Claus-Peter Reisinger, Rob Eek, Kaspar Hallenberger, Martin Friedrich
  • Process for the production of cross-linked rubber particles
    Patent number: 6605671
    Abstract: The invention discloses an improved process for the production of cross-linked rubber particles. The cross-linking agents are added to the aqueous rubber dispersions and converted at relatively high temperatures without inertization of the reaction mix and without pressurizing of an inert gas. The cross-linked rubber particles are suitable, for example, for the production of technical rubber products and for various tire components.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 12, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventor: Werner Obrecht
  • Dynamic mixer
    Publication number: 20030147304
    Abstract: A mixer is which comprises a housing (1) with filling (4) and emptying (5) openings, two corotating stirrers (2) and (3) and driveers for moving the stirrers (2) and (3), wherein one stirrer (2) is arranged centrally in the housing (1), the stirrer (2) comprising at least a drive shaft (6), at least one transverse beam (7) fitted to the latter and at least one, preferably at least two, stirring arms (8, 9) fitted in each case at their ends to this transverse beam (7).
    Type: Application
    Filed: January 24, 2003
    Publication date: August 7, 2003
    Applicant: Bayer Aktiengesellschaft
    Inventors: Heinrich Schuchardt, Klemens Kohgruber
  • Additive mixtures containing thermoplastic moulding compositions
    Patent number: 6602939
    Abstract: A thermoplastic molding composition suitable for preparing molded articles having improved mechanical properties is disclosed. The composition contains A) a (co)polymer of at least one monomer selected from the group consisting of styrene, &agr;-methylstyrene, nuclear-substituted styrene, methyl methacrylate, acrylonitrile, methacrylonitrile, maleic anhydride and N-substituted maleimide , and B) a graft polymer of B.1) at least one member selected from the group consisting of styrene, &agr;-methylstyrene, nuclear-substituted styrene, methyl methacrylate, acrylonitrile, methacrylonitrile, maleic anhydride and N-substituted maleimide on B.2) a rubber having a glass transition temperature of ≦10° C. and C) a mixture of at least 3 components selected from I) metallic compounds, II) esters III) amides and IV) certain specified compounds exemplified by oil or wax.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: August 5, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventor: Herbert Eichenauer
  • Agrochemical formulations
    Patent number: 6602823
    Abstract: Agrochemical formulations comprising a) at least one agrochemically active compound, b) 2-ethyl-hexanol alkoxylate of the formula  in which P represents E represents —CH2—CH2— and the numbers 8 and 6 are average values and c) optionally additives, a process for preparing these formulations and their use for applying the active compounds they comprise are described.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: August 5, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Röchling, Anne Suty-Heinze, Karl Reizlein, Udo Reckmann
  • Heterocyclically substituted aromatic amino compounds with a herbicidal effect
    Patent number: 6602826
    Abstract: The invention relates to new substituted aromatic amino compounds of the general formula (I) in which R1, R2, R3, R4 and Z have the meanings given in the description, to a process for their preparation, and to their use as herbicides.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: August 5, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Roland Andree, Mark Wilhelm Drewes, Kurt Findeisen, Joachim Kluth, Karl-Heinz Linker, Klaus-Helmut Müller, Otto Schallner, Markus Dollinger
  • Process for lining canals, ditches and pipes with a non-sagging polyurethane/geofabric composite
    Patent number: 6602025
    Abstract: A surface of a canal, ditch or pipe is lined with a polyurethane/geofabric composite. A non-sagging polyurethane composition is applied to the canal, ditch or pipe surface, a geofabric is contacted with that surface in a manner such that the geofabric becomes impregnated with the non-sagging polyurethane composition which cures to form a polyurethane/geofabric composite. The non-sagging polyurethane is a reaction product of a polyisocyanate, a high molecular weight polyhydroxyl compound and a compound having at least 2 amino groups. A low molecular weight diol or triol, filler and catalyst are optional components. These composites are particularly useful in lining cracked or broken concave or angled surfaces.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: August 5, 2003
    Assignee: Bayer Corporation
    Inventors: Peter H. Markusch, Ralf Guether
  • Method for producing quickly decomposable solid pharmaceutical preparations
    Patent number: 6602520
    Abstract: Rapidly disintegrating preparations containing at least one active pharmaceutical ingredient and at least one excipient can be obtained by a simple process in which at least the predominant part of the complete composition of the ingredients for the preparation to be produced is granulated, the resulting granules and, where appropriate, the remainder of the ingredients are shaped in the presence of liquid virtually without pressure, and the resulting shaped articles are dried.
    Type: Grant
    Filed: January 3, 2002
    Date of Patent: August 5, 2003
    Assignee: Bayer AG
    Inventors: Marco Schroeder, Klaus-Jürgen Steffens
  • Process of making elastane yarn
    Patent number: 6602453
    Abstract: Described are a process for producing elastane yarn having a linear density of at least 2500 dtex by the wet spinning process and the thereby producible coarse linear density elastane yarn having a wide cross section and a low residual solvent content. The process comprises the steps of spinning an up to 35% strength by weight stable-viscosity elastane solution into a coagulation bath, washing and optionally drawing, drying by contact heating, setting, spin finishing and winding the yarn, the filaments leaving the coagulation bath passing around a diverting roller disposed just above the coagulation bath liquid, the as-spun filament linear density amounting to not more than 1% of the value of the final linear density, the jet stretch ratio being within the range from 0.5 to 50, the contact heating temperature being at least 220° C. and the contact time of the elastane yarn being at least 2 seconds.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: August 5, 2003
    Assignee: Bayer Faser GmbH
    Inventors: Ulrich Reinehr, Tilo Sehm, Wolfgang Anderheggen, Toni Herbertz
  • Method of production of benzofuranone oximes
    Patent number: 6603025
    Abstract: The present invention relates to a novel process for preparing known benzofuranone oximes, and to a novel process for preparing known benzofuranyl alkanoates which are used as intermediates in the synthesis sequence.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: August 5, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhard Lantzsch, Herbert Gayer, Peter Gerdes, Walter Hübsch, Lubbertus Mulder, Bernd Gallenkamp, Matthias Decker