Abstract: Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vaccines containing same, methods for production of same and methods for use of same.

Abstract: A dispersive optical spectrometer is disclosed which comprises light detection means, dispersion means for separating light radiation into spectral components and for directing the spectral components toward the light detection means, means for admitting light radiation into the entrance focal plane and for directing the light radiation toward the dispersion means, the light radiation admitting means including a plurality of spaced-apart apertures, and light transmission means for transmitting light radiation from a light source to one or more of the apertures. In a preferred embodiment, the apertures form a two-dimensional, rectilinear array for producing non-overlapping spectra.

Abstract: A simplified water brake unit has greater capacity per unit weight and is readily maintained due to a two piece readily disassembled housing, one part of which provides a firm, accurate support for the stator, and which also has longer seal life because of a seal chamber bleed which relieves the high pressure from behind the inner high pressure seal by providing a communication to the inlet.

Abstract: Specific common nucleolar antigens are found in a broad range of human malignant tumor specimens and have been isolated, extracted and purified. Antibodies and antisera specific to these nucleolar antigens are harvested from non-human hosts and used for detection of human cancer cells. Disclosed are (1) methods for isolating the nucleolar antigens, obtaining them in substantially purified form, producing the specific antibodies, obtaining them in substantially purified form, and using the antisera and antibodies induced by the nucleolar antigens in diagnostic procedures for detecting human cancer cells, and (2) diagnostic kits comprising specific antibodies and antisera.

Abstract: Disclosed are monoclonal antibodies against lens epithelial cells and methods of producing them. Continuous cell lines for producing monoclonal antibodies to lens epithelial cells are disclosed. Human lens epithelial antibody producing cells are fused with myeloma cells to provide a fused hybrid, the hybrid is cultured, and antibodies specific to human lens epithelial cells are collected.Proliferation of remnant lens epithelial cells after extracapsular extraction is prevented by instilling the monoclonal antibodies specific to lens epithelial cells into the anterior chamber of the human eye and allowed to interact with the lens epithelial cells. Complement is then instilled into the anterior chamber to cause lysis or other damage to the lens epithelial cells thereby preventing them from multiplying and migrating to cover the surface of the lens capsule left in place. This can be done at the time of extracapsular cataract extraction or later to remove a second cataract caused by proliferation of these cells.

Abstract: Disclosed is an improved dietary protein mineral module composed of a high quality protein, such as calcium-sodium caseinate, and electrolytes (minerals) combined in a fixed ratio so that when the protein concentration in water is 2.2 g/100 cc (a normal concentration) the normal mineral requirements are met and in which the dietary acid content (chloride) is reduced to a maximum of 2.0% dry weight and there is increased phosphorus content (a minimum of 1.0% up to 4.0% dry weight). The improved module has been quite successful in treating specific problems in infants who have not responded well to any of the existing commercial formulas. These include: acquired monosaccharide intolerance or intractable diarrhea of infancy; weaning from total parental nutrition; alteration of the renal solute load in infants with renal or congenital heart disease; and prevention of acidosis in infants thereby resulting in better growth.

Abstract: An eddy current machine has a disc-type rotor mounted on a transversely disposed shaft and circularly arranged sets of adjacent poles of different polarity. A uniform flux path is provided for the magnetic lines of flux. The air gap between the pole faces and the rotor can be adjusted. Cooling fluid circulates around both rotor and pole faces.

Abstract: A dispersive optical spectrometer is disclosed which comprises light detection means, dispersion means for separating light radiation into spectral components and for directing the spectral components toward the light detection means, means for admitting light radiation into the entrance focal plane and for directing the light radiation toward the dispersion means, the light radiation admitting means including a plurality of spaced-apart apertures, and light transmission means for transmitting light radiation from a light source to one or more of the apertures.

Abstract: An insert for insertion into a circularly cross-sectioned sample tube for use in nuclear magnetic resonance spectrometry for reducing temperature variations in the sample and dispersing heat generated. The insert includes two spaced end plugs having arcuate sides to thermally mate with the interior of the sample tube. The end plugs include a venting passageway for allowing flow of fluids past the plugs when the insert is moved into and out of a sample in the tube. An elongate circular rod is positioned between and connected to the end plugs and positioned to be coaxially positioned in the sample tube. The rod has a cross-sectional area of less than the end plugs for providing an annular sample chamber when positioned in a sample tube. The end plugs and the rod are of beryllium oxide for conducting heat from and reducing temperature variations in the sample tube. The sample tube may also be of beryllium oxide.

Abstract: A test substrate, including a semi-permeable membrane which retains bacteria on the membrane and which has a net positive surface charge to permit coloring of bacteria thereon with a cationic dye, without the membrane adsorbing substantial amounts of said dye. Substrate is included in a kit for detecting bacteria.

Abstract: A control system for providing controllable direct current power for energizing an electromagnetic brake having an alternating current power supply and a power rectifier for converting and supplying direct current power to the brake. A power switch controls the amount of direct current power supplied to the brake. A control circuit controls the actuation of the power switch and includes a brake control actuating a variable output transformer. The output from the transformer is converted to a variable pulse width signal for actuating the power switch. Preferably, the transformer is a variable ratio transformer having a movable core connected to the operator's control. A battery charger and batteries may be connected to the ouput of the power rectifier for maintaining brake power in the event of alternating current line failure. Multiple transistor power switches connected to separate brake coils maintain a portion of brake power in the event of partial equipment failure.

Abstract: A catalase method and apparatus are disclosed for direct measurement of bacterial growth activity in the presence and absence of antibiotics, and for the determination of antibiotic sensitivity directly from clinical specimens within one and one-half to four or five hours if the agent is a catalase producer. If not, antibiotic sensitivity is measured by light obscuration. The total bacterial counts of normal flora and artifacts in the growth medium do not affect the tests. Preferably, a transducer or other pressure-measuring technique determines the positive pressure produced by the catalytic decomposition of peroxide. Aerosolization of pathogenic organisms is avoided by combining hydrogen peroxide with a quaternary compound which kills the bacteria and at the same time frees additional catalase to yield total catalase titers which are very reproducible and accurate. The method and apparatus easily detect Staphylococcus, Pseudomonas, Proteus, E. coli, and other catalase-producing bacteria.

Abstract: A method for detecting occult blood in aqueous samples of human specimens, particularly aqueous suspensions of fecal matter is disclosed. The method comprises acidifying an aqueous test sample, which in the case of fecal matter has been treated with lysozyme to clear the suspension; separating the liquid and solid portions of the test sample and passing the acidified liquid portion through an electro-negatively charged membrane; thereafter removing residual test liquids from the membrane; treating the membrane with a peroxidase indicator and observing the development of color on the treated membrane surface. A method for quantifying occult blood is also disclosed which comprises subjecting an aqueous sample to the disclosed detection method and comparing the color developed with a standardized scale reflecting colors developed by treating samples containing known incremental quantities of hemoglobin in accordance with the detection method of the invention.

Abstract: A simple and functional apparatus is disclosed for use in the home, field and other places in which water or other fluids can be evaluated for the presence of bacteria. Also disclosed is a convenient tablet reagent for use with liquid peroxide with the apparatus.

Abstract: A microprocessor based instrument designed to retrofit into existing perimeters utilizing the mechanics and stimulus control aspects of the existing perimeter. The device includes an array board positioned adjacent the perimeter mechanical arm and includes a multiplicity of visual indicators spatially arranged in a composite pattern of testing locations required for one or more ophthalmic testing procedures. A processor is connected to the array board for sequentially actuating the visual indicators in accordance with the testing procedure whereby the operator guides a cursor attached to the perimeter mechanical arm to align with the actuated indicators and control the location of the perimeter test stimulus. The processor includes means for sensing the position of the cursor, silently presenting a light flash to the patient, and a memory which records the patient's responses.

Abstract: First and second electro-optical display devices for displaying visual acuity targets, one of which is adapted to be viewed by a patient and the other of which is adapted to be viewed by an examiner. An electronic memory is connected to the display devices containing a plurality of acuity targets stored in various orientations for presentation to the display devices. Controls are provided in an examiner's console for selecting one of a plurality of available target sizes, "zoom" increasing size or decreasing size, selecting a single or a line of multiple target characters, providing normal or reverse video presentation, changing the orientation of the target characters, and providing a blank screen. The size of the targets is varied by changing the dimensions of each of the targets about its own center and in the case of multiple targets, maintaining proportional spacing between the targets as the size of the targets vary.

Abstract: A test tool and a method of testing is disclosed for testing for leaks in apparatus having a bore and a landing surface, such as blowout preventers, wellheads, casing hangers, and the like. The test tool is connected to pipe having a passage therethrough, which has a landing surface for landing on the landing surface of the bore, bypass passages automatically closed on landing and during testing, packing means for effecting a seal in the bore, a pressure relief valve and hydraulic passages communicating with the passage in the pipe, the packing means, and the relief valve which opens at a predetermined pressure. The packing is set either hydraulically, mechanically or by a combination thereof. The packing is set hydraulically by a piston and cylinder which are activated by hydraulic setting pressure in the passages and then hydraulic test pressure is released by the relief valve to the space above the packing for testing the apparatus.

Abstract: A portable eye examination system cart is provided with an instrument console which conveniently supports eye examination devices, an electric power system effective to provide electrical power to the eye examination devices which are electrical, including automatic turn on and off switches when removing and replacing electrical eye examination devices, and a monitor panel. The electrical system may include a rechargeable battery system and recharging circuitry. The cart includes storage areas for convenient location of ophthalmic drugs and examination supplies, small instrument accessories, spare lamps and parts, patient record charts and other miscellaneous items. The cart includes easily manipulated, lockable covers to secure all instruments and supplies from threat of unauthorized use, and the cart is constructed of lightweight material for good maneuverability with dimensions appropriate for convenient use between hospital beds, movement through hospital corridors, and the like.

Abstract: Wastewaters heavily laden with organic compounds and containing viruses and other microbiological flora are sterilized and maintained sterile for prolonged periods of time by the addition of a base, such as lime, and a quaternary compound, preferably cetyl pyridinium chloride, in amounts to maintain the pH of the wastewaters at about 9-11, or higher, and with sufficient quaternary compound for suspended solids present. This prevents the formation of methane gases, which are tentative hazards in that they are inflammable, asphyxiant and narcotic. Similarly, toilets are rendered sterile by the addition of the base and quaternary compound so that, upon flushing, aerosols generated will not contain active infectious agents. All bacteria and fungi are inactivated under these basic conditions by the addition of quaternary compounds. Viruses are also inactivated under these basic conditions but only with quaternary compounds which contain the pyridinium moiety.

Abstract: A catheter is disclosed which is simple to use, avoids the problems with prior catheters, which is fail-safe and fool-proof and one by which the patient cannot injure himself. The catheter comprises a flexible inner tubular member forming a flow duct, snuggly and slidably disposed in an outer tubular member, and having a rounded expansion tip at its inner end comprised of a plurality of prongs biased outwardly and operable to expand and open on inward movement of the inner tubular member in the outer tubular member to a position where the prongs are beyond the inner end of the outer member and to retract on movement of the inner tubular member outwardly in the outer tubular member to a position where at least a portion of the prongs are within the outer tubular member.