Patents Assigned to Baystate Health, Inc.
  • P53 SILENCED ENDOTHELIAL PROGENITOR CELLS FOR DIABETES
    Publication number: 20190151358
    Abstract: The invention provides, inter alia, methods for treating vascular deficiencies, including those in diabetic subjects, by transplanting endothelial progenitor cells with transiently reduced p53 expression.
    Type: Application
    Filed: June 26, 2018
    Publication date: May 23, 2019
    Applicant: Baystate Health, Inc.
    Inventor: Sabyasachi Sen
  • p53 silenced endothelial progenitor cells for diabetes
    Patent number: 10016458
    Abstract: The invention provides, inter alia, methods for treating vascular deficiencies, including those in diabetic subjects, by transplanting endothelial progenitor cells with transiently reduced p53 expression.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: July 10, 2018
    Assignee: Baystate Health, Inc.
    Inventor: Sabyasachi Sen
  • P53 SILENCED ENDOTHELIAL PROGENITOR CELLS FOR DIABETES
    Publication number: 20130273014
    Abstract: The invention provides, inter alia, methods for treating vascular deficiencies, including those in diabetic subjects, by transplanting endothelial progenitor cells with transiently reduced p53 expression.
    Type: Application
    Filed: March 11, 2013
    Publication date: October 17, 2013
    Applicant: Baystate Health, Inc.
    Inventor: Sabyasachi Sen
  • Cytology device
    Patent number: 8070691
    Abstract: A cytology device and a method of use thereof are described. The cytology scraper comprises a scraping element that provides increased tissue removal capabilities over conventional cytology brushes. The edges of the scraping element can also simultaneously dilate strictures during the tissue removal procedure.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: December 6, 2011
    Assignees: Cook Medical Technologies LLC, Baystate Health, Inc.
    Inventors: David J. Desilets, Richard W. Ducharme
  • Balloon endoscope device
    Patent number: 8038598
    Abstract: A balloon endoscope device having a shaft with a distal end that allows for blunt dissection is provided. The shaft utilizes a plurality of separately inflatable balloons that alone or together with exterior functional channels (e.g., instrument channels, air channels, water channels, suction channels) circumferentially surround the distal end of the shaft to better position and maneuver the distal end as it advances through tissue planes and once it reaches a target working space or operative site.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: October 18, 2011
    Assignee: Baystate Health, Inc.
    Inventor: Gerald J. Khachi
  • PHOSPHOLIPASE C ZETA MEDIATED OOCYTE ACTIVATION, COMPOSITIONS FOR USE THEREIN, AND ASSAYS FOR DETECTING AND IDENTIFYING AGENTS FOR TREATING MALE INFERTILITY
    Publication number: 20080175827
    Abstract: The invention relates to the use of phospholipase C zeta in inducing or promoting the activation of oocytes, preferably human oocytes, nuclear transfer embryos, parthenogenic embryos, cross species embryos and during in vitro fertilization. The invention further relates to methods of detecting levels of expression of phospholipase c zeta in sperm as a means of detecting male infertility. The invention also relates to the use of phospholipase C zeta to treat male infertility. Still further the invention relates to the recombinant cells that are engineered to express phospholipase C zeta, preferably under inducible conditions. Also, the invention relates to antibodies specific to phospholipase C zeta, preferably human phospholipase C zeta.
    Type: Application
    Filed: November 19, 2007
    Publication date: July 24, 2008
    Applicants: Michigan State University, University of Massachussetts, Baystate Health, Inc.
    Inventors: Rafael A. Fissore, Pablo Visconti, Manabu Kurokawa, Sook-Young Yoon, Daniel R. Grow, Teru J. Jellerette, Jose Bernardo Cibelli, Pablo Juan Ross