Patents Assigned to Baystate Medical Center
  • Methods, compositions and kits for assaying mitochondrial function
    Patent number: 9915647
    Abstract: The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: March 13, 2018
    Assignees: BAYSTATE MEDICAL CENTER, INC., UNIVERSITY OF MASSACHUSETTS
    Inventors: Nagendra Yadava, Alejandro Pablo Heuck, Chul Kim
  • Methods, compositions and kits for assaying mitochondrial function
    Patent number: 9513281
    Abstract: The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: December 6, 2016
    Assignees: BAYSTATE MEDICAL CENTER, INC., UNIVERSITY OF MASSACHUSETTS
    Inventors: Nagendra Yadava, Alejandro Pablo Heuck, Chul Kim
  • METHODS, COMPOSITIONS AND KITS FOR ASSAYING MITOCHONDRIAL FUNCTION
    Publication number: 20150198585
    Abstract: The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity.
    Type: Application
    Filed: October 20, 2014
    Publication date: July 16, 2015
    Applicants: University of Massachusetts, Baystate Medical Center, Inc.
    Inventors: Nagendra Yadava, Alejandro Pablo Heuck, Chul Kim
  • METHODS, COMPOSITIONS AND KITS FOR ASSAYING MITOCHONDRIAL FUNCTION
    Publication number: 20130164774
    Abstract: The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity.
    Type: Application
    Filed: April 6, 2012
    Publication date: June 27, 2013
    Applicants: University of Massachusetts, Baystate Medical Center, Inc.
    Inventors: Nagendra Yadava, Alejandro Pablo Heuck, Chul Kim
  • METHODS, COMPOSITIONS AND KITS FOR ASSAYING MITOCHONDRIAL FUNCTION
    Publication number: 20120301912
    Abstract: The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity.
    Type: Application
    Filed: April 6, 2012
    Publication date: November 29, 2012
    Applicants: University of Massachusetts, Baystate Medical Center, Inc.
    Inventors: Nagendra Yadava, Alejandro Pablo Heuck, Chul Kim
  • Method for determining the presence of mutated BRCA protein
    Patent number: 5965377
    Abstract: This invention relates to a simple and reliable screening method for determining an individual's susceptibility to breast, ovarian, colon or prostrate cancer. This invention also relates to a test kit for use in conjunction with this method. The inventive method targets a specific alteration of the BRCA protein and identifies a non-invasive source of normal cells that express this protein.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: October 12, 1999
    Assignee: Baystate Medical Center
    Inventors: Lorrie A. Adams, Timothy J. Byrne, Gabriel M. Cohn, Margaret T. Reece