Patents Assigned to BCM Developement Inc.
  • Method for the purification of taxanes
    Patent number: 6002025
    Abstract: Taxanes are purified by chromatographic separation using a phenylalkyl chromatographic resin, wherein the alkyl portion of the phenylalkyl is a C.sub.4 -C.sub.10 moiety. Taxanes such as paclitaxel, 10-deacetyltaxol, 7-epi-taxol, cephalomannine, baccatin III, baccatin V, 7-epi-DAB, 10-deactylbaccatin III ("DAB") and 9-dihydro-13-acetylbaccatin III ("DHB") and others may be purified. In accordance with the invention, taxanes are separated from each other and from other impurities common to crude taxane samples.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: December 14, 1999
    Assignee: BCM Developement Inc.
    Inventors: Michel Page, Marie-Josee Perron