Patents Assigned to Beacle Inc.
  • Virus-like particles including HBs-L antigen protein for causing immune response against HBV
    Patent number: 11471527
    Abstract: The present invention provides a virus-like particle comprising several or more types of HBs-L antigen proteins or a virus-like particle composition comprising a combination of the virus-like particles, for the purpose of provision of an antigen that triggers an immune reaction against HBV of various genotypes.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: October 18, 2022
    Assignee: BEACLE INC.
    Inventors: Yasumasa Goh, Yasunori Oda, Chinatsu Ohashi, Kentaro Isotani
  • VIRUS-LIKE PARTICLES TO BE USED FOR CAUSING IMMUNE RESPONSE AGAINST HBV
    Publication number: 20200164062
    Abstract: The present invention provides a virus-like particle comprising several or more types of HBs-L antigen proteins or a virus-like particle composition comprising a combination of the virus-like particles, for the purpose of provision of an antigen that triggers an immune reaction against HBV of various genotypes.
    Type: Application
    Filed: June 5, 2018
    Publication date: May 28, 2020
    Applicant: BEACLE INC.
    Inventors: Yasumasa GOH, Yasunori ODA, Chinatsu OHASHI, Kentaro ISOTANI
  • VIRUS-LIKE PARTICLE FOR USE IN IMMUNOASSAY, BLOCKING AGENT FOR USE IN THE IMMUNOASSAY, AND KIT COMPRISING THE VIRUS-LIKE PARTICLE AND THE BLOCKING AGENT
    Publication number: 20160202251
    Abstract: An object of the present invention is to provide an immunoassay that has excellent detection sensitivity and that remarkably suppresses the detection background. The means for achieving the object is to provide a virus-like particle that contains a protein having self-organization ability, the particle being modified with a biologically active molecule at at least one cysteine residue of the protein having self-organization ability via a thiol group or thiol groups thereof.
    Type: Application
    Filed: August 1, 2014
    Publication date: July 14, 2016
    Applicant: BEACLE INC.
    Inventors: Yasumasa GOH, Yasunori ODA
  • Hollow protein nano-particles and method of introducing substances into cells
    Patent number: 7597905
    Abstract: As a versatile means for specifically and safely transporting and transferring substances (genes, proteins, compounds, etc.) into target cells and tissues, hollow nano particles comprising a protein capable of forming particles (e.g., hepatitis B virus surface antigen protein), and a biorecognition molecule introduced therein, are provided.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: October 6, 2009
    Assignee: Beacle Inc.
    Inventors: Shun'ichi Kuroda, Katsuyuki Tanizawa, Masaharu Seno, Akihiko Kondo, Masakazu Ueda
  • Substance carrier using hollow nanoparticle of hepatitis B virus protein and liposome, and method of introducing substance into cell
    Publication number: 20070059746
    Abstract: The present invention relates to a method of producing a composite particle of a nanoparticle and a liposome in which a substance to be introduced has been encapsulated, characterized in that a hollow nanoparticle containing a hepatitis B virus protein or a modification thereof is fused to the liposome in which the substance to be introduced has been encapsulated.
    Type: Application
    Filed: September 1, 2006
    Publication date: March 15, 2007
    Applicants: Japan Science and Technology Agency, Osaka University, Beacle Inc.
    Inventors: Shun-ichi Kuroda, Atsuko Ueda, Mana Nagita