Patents Assigned to Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
  • Publication number: 20240125592
    Abstract: The present disclosure relates to a beam measuring device, a sample processor including the beam measuring device, and a method of measuring a beam using the beam measuring device. The beam measuring device includes a detection unit and a light impediment unit. The light impediment unit is located between the detection unit and a light source, and is configured to generate a shadow area on the detection unit by blocking transmission of part of a beam coming from the light source. The detection unit is configured to measure the shadow area, and to determine whether the beam is divergent or inclined with respect to a predetermined optical axis based on the measurement of the shadow area. The beam measuring device may shorten the optical detection channel and ensure the detection accuracy, thereby having a compact structure. In addition, the beam measuring device may measure divergence angle and directionality, respectively.
    Type: Application
    Filed: July 21, 2023
    Publication date: April 18, 2024
    Applicant: Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
    Inventors: Wei SHI, Ruifeng MIAO, Zhonghui CHEN, Jianhua WANG
  • Publication number: 20240118186
    Abstract: The present application relates to a system or method for auto gating of QC base on population analysis. The system or method is particular useful for a sample processing instrument (for example, a flow cytometer or analyzer). The method comprise the following steps: I) providing QC beads used for testing the performance index of an equipment of interest; II) setting the equipment to collect the data of the QC beads; III) analyzing the collected data and calculating the gate position of QC beads based on the collected data; and VI) adjusting the acquisition parameters of the equipment based on the calculated gate position.
    Type: Application
    Filed: October 11, 2023
    Publication date: April 11, 2024
    Applicant: Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
    Inventors: Jianxiang DIAO, Xiaonan CAI
  • Publication number: 20240110857
    Abstract: The present disclosure relates to a liquid flow charging device for a flow cell and a flow cell comprising the liquid flow charging device. The liquid flow charging device comprises a first electrode and a second electrode. The first electrode is electrically connected to a liquid flow flowing through a flow channel assembly of the flow cell. The second electrode is located at a predetermined position on a radially outer side of the liquid flow and has a cylindrical inner peripheral surface surrounding the liquid flow. The liquid flow charging device has improved charging efficiency, stable charging performance, and enhanced safety.
    Type: Application
    Filed: November 1, 2021
    Publication date: April 4, 2024
    Applicant: BECKMAN COULTER BIOTECHNOLOGY (SUZHOU) CO., LTD.
    Inventors: Ruifeng MIAO, Wei SHI, Jingzhang WU
  • Publication number: 20240094108
    Abstract: A bubble detection device and a sample processing instrument are provided. The bubble detection device includes a body, a cover and a detection circuit board. The body includes a bottom wall and first and second side walls respectively extending from two sides of the bottom wall. The bottom, first and second side walls define a groove for accommodating a sample pipe of a sample processing instrument, and first and second holes are respectively provided in the first and second side walls to allow light from a light source to pass through the sample pipe. The cover includes a top portion for covering the groove and first and second side portions attached to the body. The detection circuit board includes the light source and a photoelectric sensor and is attached to the body such that they are aligned with the first and second holes respectively to sense intensity of the light passing through the sample pipe. The sample processing instrument includes the bubble detection device.
    Type: Application
    Filed: November 1, 2021
    Publication date: March 21, 2024
    Applicant: BECKMAN COULTER BIOTECHNOLOGY (SUZHOU) CO., LTD.
    Inventors: Ailin ZHANG, Xi LIU, Ruifeng MIAO, Xin JIN
  • Publication number: 20240094113
    Abstract: The invention relates to a cuvette assembly for a sample processor, a flow cell for a sample processor comprising the cuvette assembly, and a sample processor comprising the cuvette assembly or the flow cell. The cuvette assembly comprises a cuvette body and a reflector. The cuvette body is in the shape of a rectangular parallelepiped and comprises a sample detection channel vertically penetrating the cuvette body. The cuvette body has long sides and short sides in a horizontal section. The reflector has a flat surface attached to a first side surface extending along one of the long sides of the cuvette body and a spherical surface that is opposite to the flat surface and has a truncated lower half. The reflector is positioned so that it is flush with a lower surface of the cuvette body and a center of sphere of the spherical surface falls into the sample detection channel, and the reflector extends along the long side and exceeds the short side.
    Type: Application
    Filed: November 1, 2021
    Publication date: March 21, 2024
    Applicant: BECKMAN COULTER BIOTECHNOLOGY (SUZHOU) CO., LTD.
    Inventors: Wei SHI, Xianghua SHI, Jianhua WANG, Linqun TANG
  • Publication number: 20240085305
    Abstract: The present application discloses a system and a method for calculating a droplet delay time in a liquid flow of a sorting device, and a sorting device.
    Type: Application
    Filed: December 28, 2021
    Publication date: March 14, 2024
    Applicants: BECKMAN COULTER BIOTECHNOLOGY (SUZHOU) CO., LTD., BECKMAN COULTER, INC.
    Inventors: Jeff DEGEAL, Robert BURR, John TYKSINSKI, Jingzhe ZHAO, Sheng YU, Xuewen QIAO
  • Publication number: 20240075477
    Abstract: The present disclosure relates to a nozzle for a sample processor, a carrier of a nozzle for a sample processor, a nozzle assembly for a sample processor, and a sample processor. The nozzle includes a body and an orifice. The body is adapted to be loaded and held in the carrier. The carrier can be slidably inserted into the sample processor in a detachable manner. The orifice is provided in the body and is configured to inject a sample from an injector body in a predetermined mode. An end surface of the body is adapted to abut against an end surface of the injector body along a sample injection direction. The nozzle assembly and the sample processor according to the present disclosure include the above-described nozzle and carrier. With the aid of the carrier, it is not necessary to install the nozzle to the injector body upstream of the nozzle, so that various adjustment operations when reinstalling the nozzle can be omitted, thereby simplifying the process of reinstalling the nozzle.
    Type: Application
    Filed: January 24, 2022
    Publication date: March 7, 2024
    Applicants: BECKMAN COULTER BIOTECHNOLOGY (SUZHOU) CO., LTD., BECKMAN COULTER, INC.
    Inventors: Wei SHI, Jingzhang WU, Erwin SCHOLZ
  • Publication number: 20240012220
    Abstract: The present disclosure relates to a device for mounting an optical element and a sample processing instrument including the device for mounting an optical element. The device for mounting the optical element includes: a frame; a mount fitted in the frame in a translatable but non-rotatable manner and having a mounting portion for accommodating the optical element; and an adjusting nut attached to the frame in a rotatable but non-translatable manner. The adjusting nut has a screw and a head located at an end of the screw for operation, and the mount has a threaded portion engaged threadedly with the screw, such that when the adjusting nut rotates, the mount translates relative to the frame. The device and the sample processing instrument according to the disclosure can allow adjustment of an optical element while preventing the latter from being off-center.
    Type: Application
    Filed: July 6, 2023
    Publication date: January 11, 2024
    Applicant: Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
    Inventors: Jingzhang WU, Wenlei FANG, Jianhua WANG
  • Publication number: 20230121733
    Abstract: The present disclosure relates to a fluid system for a sample processor and a sample processor including the fluid system. The fluid system includes a sample line, a processing fluid line, a vacuum line, and an air pump. The sample line communicates a sample container with a sample port of a flow cell unit. The processing fluid line communicates a sheath fluid container with a processing fluid port of the flow cell unit. The vacuum line is in communication with the flow cell unit. The air pump includes a first output port and a second output port. Pressurized gas is generated at the first output port, and the first output port is in communication with the sample container and the sheath fluid container. A vacuum is generated at the second output port, and the second output port is in communication with a vacuum port of the flow cell unit through the vacuum line.
    Type: Application
    Filed: November 30, 2021
    Publication date: April 20, 2023
    Applicants: Beckman Coulter, Inc., Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
    Inventors: Linqun TANG, Simon NAVA, Juntao YUAN, Liang SHI
  • Patent number: D992751
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: July 18, 2023
    Assignee: Beckman Coulter Biotechnology (Suzhou) Co., Ltd.
    Inventors: Xi Liu, Cheng Li, Jingzhang Wu