Patents Assigned to Beckman Coulter, Inc.
  • Patent number: 11408813
    Abstract: In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: August 9, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: George C. Malachowski, Paul Barclay Purcell, Edward Allan Stanton, Kenneth Michael Evans
  • Patent number: 11402386
    Abstract: An integrated sample processing system including an analyzer and a mass spectrometer is disclosed. The integrated sample processing system can perform multiple different types of detection, thereby providing improved flexibility and better accuracy in processing samples. The detection systems in the sample processing system may include an optical detection system and a mass spectrometer.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: August 2, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Aaron Hudson, Takayuki Mizutani, Subhasish Purkayastha, Thomas W. Roscoe
  • Patent number: 11371944
    Abstract: Embodiments of the present invention encompass systems and methods for detecting the presence of a test pad on a test strip. Exemplary techniques involve receiving a test strip having at least one test pad, where individual test pads have a pad width with ink disposed on two ink zones at two opposing sides of the width of the pad, illuminating the at least one test pad with a light source, detecting reflected signals from the test pad, generating an image comprising of pixels of the two ink zones based on the reflected signals, detecting the presence of each of the ink zones by comparing the number of consecutive pixels against a predetermined threshold, and determining the presence of the test pad on the test strip if two ink zones are detected within the pad width.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: June 28, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Jindan Zhou, Carlos Ramirez, Patricio Vidal, Christophe Godefroy, Gregory Yeager, Jorge Leon
  • Patent number: 11320814
    Abstract: A diagnostic instrument failure prediction and remediation system may include a compressed air system and a computer configured to analyze stored information regarding the compressed air system to predict likely failures of the compressed air system. Such analysis may utilize information such as duty cycle information for a compressor comprised by the compressed air system and pressure information for a pressure sensor for a compressed air system.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: May 3, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Brian J. Littman, Xiao Yin
  • Patent number: 11311871
    Abstract: Misalignment of intersecting devices on a diagnostic instrument may be detected and remediated using a system comprising components such as an accelerometer, a plurality of strain gauges and a device comprising a processor and a memory (e.g., a computer). In such a system, the accelerometer may be adapted to detect movement of the diagnostic instrument. The device comprising the processor and the memory may be configured to, for each of the structural elements of the diagnostic instrument, determine whether an alignment change has taken place in that structural element based on analyzing measurements made by the plurality of strain gauges. The device comprising the processor and the memory may also be configured to, for each structural element where an alignment change is determined to have taken place, trigger a remediation for each device from a set of devices impacted by the alignment change of that structural element.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: April 26, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Brian J. Littman, Pradeep Pasumarthy
  • Patent number: 11263433
    Abstract: Automatic substance preparation and evaluation systems and methods are provided for preparing and evaluating a fluidic substance, such as e.g. a sample with bodily fluid, in a container and/or in a dispense tip. The systems and methods can detect volumes, evaluate integrities, and check particle concentrations in the container and/or the dispense tip.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 1, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Takayuki Mizutani, Leila Nazemi, Arthur Conan Dewitt, Stephanie Yancey, Marie Willette, Rebecca Busacker, Matt Barnabei, Katsuhiro Seo, Shigeru Fujii, Kazuki Umebara
  • Patent number: 11249075
    Abstract: The method involves drying down dye-conjugated reagents in separate locations in a reaction vessel so that the dyes don't non-specifically interact with each other during drying. This invention thus improves multiplex binding assays by eliminating erroneous results caused by dyes' being non-specifically attached to each other when dried down together.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: February 15, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Sridhar Ramanathan, Badri Narayanan Natarajan
  • Patent number: 11249098
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method using magnetic beads containing negatively charged carboxyl groups extending from the surface of the magnetic beads.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: February 15, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi
  • Patent number: 11208527
    Abstract: The present invention provides water soluble photoactive macromolecular complexes and methods for detecting an analyte in a sample by using a binding agent conjugated to a water soluble photoactive macromolecule.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: December 28, 2021
    Assignee: Beckman Coulter, Inc.
    Inventors: Arunkumar Easwaran, Sergei Gulnik
  • Patent number: 11209451
    Abstract: Certain types of automated medical analysis equipment are used to analyze blood or other fluids. The equipment may thus use various diluents or reagents that allow the blood or other fluids to be run through the analysis equipment for analysis and data collection. Disclosed is a diluent preparation module that combines purified water and reagent concentrate for use by this equipment. Also disclosed is a diluent preparation unit that combines more than one diluent preparation modules for redundancy and back-up purposes. Also disclosed are systems for supplying the Diluent prepared by the diluent preparation module or diluent preparation unit to one or more analytic instruments.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: December 28, 2021
    Assignee: Beckman Coulter, Inc.
    Inventor: Craig R Veiner
  • Patent number: 11199558
    Abstract: A method of establishing a sample tube set which is adapted to be processed by a laboratory automation system.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: December 14, 2021
    Assignee: Beckman Coulter, Inc.
    Inventor: Sebastian Streibl
  • Patent number: 11199557
    Abstract: Experimental studies can be conducted in an environment where one or more laboratories communicate with a network instrument monitoring center over a network. In such an environment, an individual at the network instrument monitoring center can be enabled to simultaneously oversee studies at multiple remote laboratories, rather than requiring dedicated individuals at each of the laboratories to oversee the studies at their respective labs.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: December 14, 2021
    Assignee: Beckman Coulter, Inc.
    Inventors: Caren E. Parker, Craig R. Cole, Sadasiva R. Guntupalli
  • Patent number: 11195611
    Abstract: Described herein are database systems including one or more remote analytical instruments operably connected to one or more servers. The instruments can transmit rich data to the servers, and the one or more servers can compile a database of the rich data. One or more processors associated with the servers can be configured to execute a data analytics program on the database to identify a stochastic phenomenon or to process the data and present in real-time at a location of the one or more instruments comparison information about the instruments.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: December 7, 2021
    Assignee: Beckman Coulter, Inc.
    Inventor: Martha C. Davis
  • Patent number: 11169060
    Abstract: A filtering device is provided to an analyzing instrument to block the passage of oversized particles that may otherwise clog the aperture of a sample analyzing device. The filtering device can be arranged to be proximate to the mixing chamber. In certain examples, the filtering device is placed at or adjacent an output port of the mixing chamber.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 9, 2021
    Assignee: Beckman Coulter, Inc.
    Inventors: Gabriel Santos, Janet F. Reyes, Gregory M. Colella
  • Patent number: 11167936
    Abstract: Disclosed aspects relate to a conveyance system and method for conveying a plurality of object carriers. The conveyance system comprises at least one first conveyor lane section, and at least, two second conveyor lane sections. The conveyance system further comprises a rotatable diverting element for diverting an object carrier of the plurality of object carriers between the at least one first conveyor lane section and one of the at least two second conveyor lane sections of the conveyance system.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: November 9, 2021
    Assignee: Beckman Coulter, Inc.
    Inventors: Michael Eberhardt, Manuel Sickert, Luciano Brueggemann
  • Patent number: 11114205
    Abstract: Embodiments may include an automated method for evaluating an infection status associated with a blood sample obtained from an individual. Methods may include determining, using a first module, a white blood cell concentration associated with the blood sample. In addition, methods may include determining, using a second module, a monocyte volume measure associated with the blood sample. Methods may include evaluating, using a data processing module, the infection status associated with the blood sample. The data processing module may include a processor and a computer readable medium. The computer readable medium may be programmed with a computer application. This computer application, when executed by the processor, may cause the processor to calculate a parameter using a function comprising the white blood cell concentration and the monocyte volume measure. The computer application may also cause the processor to evaluate the infection status associated with the blood sample based on the parameter.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: September 7, 2021
    Assignee: Beckman Coulter, Inc.
    Inventors: Robert T. Magari, Diana B. Careaga, Fernando P. Chaves, Liliana M. Tejidor
  • Patent number: D928194
    Type: Grant
    Filed: July 28, 2018
    Date of Patent: August 17, 2021
    Assignee: BECKMAN COULTER, INC.
    Inventors: Brittany R. Baker, Daniel Sunoh Choe, Andrew Cottrell, Dana Vajen Habig, Tony J. Riley, Brandon S. Roseen, Mindie Seh Wha Te, XiaoYin Wang, Chad M. Weber
  • Patent number: D938612
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: December 14, 2021
    Assignee: BECKMAN COULTER, INC.
    Inventors: Niandong Liu, Amit Sawhney, Daniel C. Massa
  • Patent number: D957416
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: July 12, 2022
    Assignee: BECKMAN COULTER, INC.
    Inventors: Nicholas Everhart, Dana Vajen Habig, Shaohui Qiu, Andrew Cottrell, Daniel Sunoh Choe
  • Patent number: D958152
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: July 19, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Adam Matthew Torres, Hernando Salas