Patents Assigned to Becton Dickinson and Company
  • Publication number: 20220146545
    Abstract: An automated analyzer that receives samples prepared for analysis in an automated pre-analytical module and a method of operation of such automated analyzer. The automated analyzer includes a shuttle transfer station that receives a shuttle carrier from the automated pre-analytical system. The shuttle transfer station has a clamping assembly for the shuttle. The clamping assembly has jaws that advance engagement members into contact with a bottom portion of sample containers disposed in the shuttle. The clamping assembly secures the sample containers in the shuttle when sample is aspirated from the sample containers. The automated analyzer also has a multichannel puncture tool that is adapted to be carried by a robotic gripper mechanism. The multichannel puncture tool has multiple puncture members that each defines a channel Each channel is in communication with a different trough in the consumable. A pipette can pass through the channel in the puncture tool.
    Type: Application
    Filed: November 10, 2021
    Publication date: May 12, 2022
    Applicant: BECTON DICKINSON AND COMPANY
    Inventors: Michael T. VanSickler, Neil G. Terry, Brian Bell, Steven C. Rotundo, Stephen Robert LaChance, Alyssa Shedlosky
  • Publication number: 20220143323
    Abstract: Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 12, 2022
    Applicant: Becton, Dickinson and Company
    Inventors: Michael W. Howlett, James V. Mercer, Amelio Paolucci
  • Patent number: 11324919
    Abstract: A catheter assembly may include a catheter adapter, which may include a distal end, a proximal end, and a lumen extending therethrough. The catheter assembly may also include a septum slidably disposed within the lumen. The septum may include a distal end, a proximal end, and a barrier disposed between the distal end of the septum and the proximal end of the septum. The barrier may divide an interior of the septum into a distal cavity and a proximal cavity. A distal face of the barrier may include a protrusion. The barrier may include a slit extending through the protrusion for selectively opening fluid communication between the distal cavity and the proximal cavity.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Yiping Ma
  • Patent number: 11327003
    Abstract: Non-parametric transforms such as t-distributed stochastic neighbor embedding (tSNE) are used to analyze multi-parametric data such as data derived from flow cytometry or other particle analysis systems and methods. These transforms may be included for dimensionality reduction and identification of subpopulations (e.g., gating). By nature, non-parametric transforms cannot transform new observations without training a new transformation based on the entire dataset including the new observations. The features described parameterize non-parametric transforms using a neural network thereby allowing a small training dataset to be transformed using non-parametric techniques. The training dataset may then be used to generate an accurate parametric model for assessing additional events in a manner consistent with the initial events.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: May 10, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Jonathan Lin, Joseph Trotter, Keegan Owsley
  • Patent number: 11324861
    Abstract: Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Ankur S. Kulshrestha, Yan Yevmenenko, Dinesh S. Kommireddy, Andrew Wong, Behzad Mottahed, Michael V. Quinn, Mildred Calistri-Yeh, Lourdes Pia L. Amora
  • Patent number: 11324922
    Abstract: A catheter assembly is disclosed that includes a catheter adapter having a port disposed on its sidewall. A valve is coupled to the port to seal the opening in the port.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Lawrence J. Trainer, S. Ray Isaacson
  • Patent number: 11328422
    Abstract: Disclosed herein include embodiments of a system, a device, and a method for sorting a plurality cells of a sample. A plurality of raw images comprising pixels of complex values in a frequency space can be generated from a plurality of channels of fluorescence intensity data of fluorescence emissions of fluorophores, the fluorescence emissions being elicited by fluorescence imaging using radiofrequency-multiplexed excitation in a temporal space. Spectral unmixing can be performed on the raw images prior to a sorting decision being made.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: May 10, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Matthew Bahr, Keegan Owsley
  • Patent number: 11324927
    Abstract: A catheter assembly may include a catheter adapter. A body of the catheter adapter may include a distal end, a proximal end, and a first lumen extending through the distal end and the proximal end. The catheter adapter may include a side port, which may extend outwardly from the body. The side port may include a second lumen, which may be perpendicular to the first lumen. The catheter assembly may include a catheter extending distally from the distal end of the body. The catheter assembly may include a valve disposed within the first lumen. The valve may include an outer surface that is cylindrical and may seal the first lumen from the second lumen. The catheter assembly may include a divider disposed with the second lumen. The divider may divide the second lumen into a plurality of openings and may increase a burst value of the valve.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Kiat Jin Cheng
  • Patent number: 11324926
    Abstract: A catheter system may include a catheter adapter, a catheter extending distally from the catheter adapter, an introducer needle extending through the catheter, a flash chamber in fluid communication with a needle lumen of the introducer needle, and a seal element. The introducer needle may include a wall defining the needle lumen, a first notch formed through the wall, and a second notch formed through the wall. The seal element may be proximal to the first notch and the second notch and within the catheter between an outer surface of the introducer needle and an inner surface of the catheter. The seal element may prevent priming fluid from travelling distal to the seal element. The seal element in conjunction with the first notch, the second notch, and the flash chamber may facilitate pressure-driven blood flow into the catheter for detection of flashback and transfixing when priming occurs prior to insertion into vasculature.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Weston F. Harding
  • Publication number: 20220137080
    Abstract: An automated pre-analytical processing method and an apparatus for pre-analytical processing of samples to be forwarded to an adjacent analyzer for analysis. Rack label information is read and communicated to a processor. From the rack label information, the processor determines where to route the rack. The pre-analytical system has a rack robot that conveys racks to discrete locations depending upon the routing information assigned to the rack by the processor. The pre-analytical system has an automated station that reads the labels of individual sample containers in the rack that are brought to the automated station on instructions from the processor. Depending on the type of sample container and the type of sample disposed therein, the samples are either prepared for analysis by the automated station or the sample containers are directly passed through the automated station. Prepared samples and passed through samples are passed individually to a batching rack.
    Type: Application
    Filed: October 18, 2021
    Publication date: May 5, 2022
    Applicant: BECTON DICKINSON AND COMPANY
    Inventors: Michael T. VanSickler, Kevin Bailey, Christopher John Tesluk, Dwight Livingston, Steven C. Rotundo, Stephen Robert LaChance, Michael J. Touma, Brian James McKeen, Gerard Sevigny
  • Patent number: 11319583
    Abstract: Disclosed herein include methods and compositions for selectively amplifying and/or extending nucleic acid target molecules in a sample. The methods and compositions can, for example, reduce the amplification and/or extension of undesirable nucleic acid species in the sample, and/or allow selective removal of undesirable nucleic acid species in the sample.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: May 3, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Eleen Shum, Glenn K. Fu
  • Patent number: 11322262
    Abstract: Systems and methods are provided for selecting colony locations. Selecting colony locations can include determine a location of a selection tool on a culture plate image, determining a location of a potential source of error on the culture plate image, comparing the location of the selection tool to the location of the potential source of error; and determining an error when the location of the selection tool overlays the location of the potential source of error.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: May 3, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Strett Roger Nicolson, Rajeev Sehgal
  • Patent number: 11318262
    Abstract: Described is a medical adapter assembly comprising an end including a neuraxial fitting that is not directly connectable to a standard luer fitting, an opposing end including a fitting connectable to an intravenous medical device, and a check valve that allows fluid flow from the end with the standard luer fitting to the end with the neuraxial fitting, but prevents fluid flow from the end with the neuraxial fitting to the end with the standard luer fitting. Methods of using the medical adapter assembly and kits containing the medical adapter assembly are also described.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: May 3, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Matthew Biggers, John Di Ubaldi, Paul P. Marici
  • Patent number: 11318459
    Abstract: A method for detecting the presence of a microorganism in a fluid sample is disclosed. The method includes providing a fluid specimen within a specimen collection container having a sidewall defining an interior therein. The interior includes a mechanical separator adapted for separating the fluid sample into first and second phases within the specimen collection container and a sensing element capable of detecting the presence of a microorganism disposed therein. The method includes subjecting the specimen collection container to applied rotational force to isolate a concentrated microorganism region. The method also includes detecting by a sensing element the presence or absence of a microorganism within the concentrated microorganism region.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: May 3, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Song Shi, Mei Yang, Klaus W. Berndt, Robert J. Losada, Jamieson W. Crawford, Ravi Attri, Christopher A. Battles, Benjamin R. Bartfeld, Gregory R. Hires
  • Patent number: 11320437
    Abstract: Dried dye reagent devices are provided. Aspects of the devices include a container having positioned therein one or more dried dye compositions that include one or more dyes stably associated with a high surface area solid support. Aspects of the invention further include methods of making and using the devices, e.g., in analyte detection applications, as well as kits containing the devices.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 3, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Margaret Inokuma, Hema Shah, Rachna Sehgal
  • Patent number: 11311459
    Abstract: A syringe adapter includes a housing having a first end and a second end positioned opposite the first end, with the housing including a connector body positioned at the first end of the housing and configured to be secured to a syringe barrel, a cannula positioned within the housing, with the cannula defining a transfer opening and a valve opening, a seal arrangement positioned within the housing and movable within the housing, and an aspiration assembly comprising an aspiration housing defining an aspiration opening, a filter received by the aspiration housing, and one-way valve received by the aspiration housing, where the valve opening of the cannula is positioned within the aspiration housing, and where air is configured to flow into the filter via the aspiration opening, into the one-way valve, and into the valve opening of the cannula.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: April 26, 2022
    Assignee: Becton Dickinson and Company Limited
    Inventors: Matthew Oshinski, Antonio Righez Mesquita
  • Patent number: 11315674
    Abstract: Improved systems and methods for medicine delivery, and in particular, improved insulin pen needles and related devices are provided. Smart injection devices record and transfer data including medicine level, delivered dose, dose confirmation, and dose time and date. Additional data captured may include glucose concentration, insulin level, carbohydrates ingested, stress level, exercise, blood pressure, and glucose high and low excursion events. Various means of data collection and analysis are provided and systems can identify and flag patients who require intervention. Smart sleeves and add sensing capability to standard insulin pens. Pen needles are provided with sensing capability to confirm and measure doses delivered by insulin pen. A two-part pen cap include a primary sleeve that connects to the insulin pen and an end cap that provides for capturing the time of dose delivery, and monitoring the hold time for a dose delivery after plunger movement.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 26, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Keith Knapp, Neil McCaffrey, Jay Butterbrodt, Margaret Taylor, Ruth Markowitz, Gary Searle, Michael Gibney, James Salemme, James Walker, Sean Sullivan, Ernest Elgin, Rita Saltiel-Berzin
  • Patent number: 11311667
    Abstract: An insulin delivery device (10) includes a cannula (40) for delivering insulin to a patient at an infusion site, a pump assembly (30), and a valve (36) for controlling the flow of insulin. A removable leak detector unit (28) is coupled to the delivery device for sensing and detecting leakage of insulin at the infusion site. The leak detector unit (28) has electrodes (56) positioned for contacting the insulin leaking from the infusion site, a sensing electrical circuit (54) and a power source (58) for operating the leak detector unit. The removable leak detector unit (28) has an electrical contact (62) for mating with an electrical contact (64) of the delivery device for electrically and operatively connecting the leak detector unit (28) to the delivery device. The leak detector unit (28) sends a signal to the pump assembly (30) and/or valve (36) to stop the flow of insulin when leakage is detected at the infusion site.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: April 26, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: James R. Petisce, Eric Bene
  • Patent number: 11315661
    Abstract: Aspects of the present disclosure include systems for use in preparing an epitope tagged biomolecule reagent. A reagent preparatory apparatus for preparing the epitope tagged biomolecule reagent from an activated biomolecule and activated epitope tag is also described. Methods for communicating and receiving an epitope tagged biomolecule reagent request and preparing the subject epitope tagged biomolecule reagents are also provided.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: April 26, 2022
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Jody Martin, Adam Wright, Paul Waterman, James Ghadiali
  • Patent number: D950720
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: May 3, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Alfred W. Prais, Nestor Rodriguez San Juan