Patents Assigned to Becton Dickinson and Company
  • Patent number: 11959849
    Abstract: Flow cytometers including light collection enhancers are provided. In embodiments, the subject flow cytometers include a flow cell, a light source, an objective lens for focusing particle-modulated light propagating within a first light collection cone and a light collection enhancer configured to collect particle-modulated light propagating along an optical path within a second light collection cone and redirect the collected light such that it is back-propagated along the same optical path and focused by the objective lens for detection. Light collection enhancers of interest include a reflective optical element (e.g., a mirror) and a condenser lens positioned between the reflective optical element and the flow cell. Methods for analyzing a sample are also provided.
    Type: Grant
    Filed: January 4, 2022
    Date of Patent: April 16, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Ihor V. Berezhnyy, Geoffrey Osborne
  • Patent number: 11957870
    Abstract: The subject invention provides a drug delivery device for injecting medicament which includes a tubular reservoir; a stopper slidably disposed in the reservoir; a spring for moving the stopper in the reservoir; at least one needle, the needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, the lumen being in direct or indirect communication with the reservoir; a needle driver for displacing the needle; and an actuator. Activation of the actuator causes the spring to move the stopper and the needle driver to displace the needle. The needle moves relative to, and separately from, the reservoir with the needle being displaced. Advantageously, with the subject invention, a drug delivery device is provided wherein a needle is moved, relative to the reservoir, in being displaced for injection. This permits control of the needle displacement separate from the reservoir.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: April 16, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Richard A Cronenberg, Lionel Vedrine, Paul Alchas
  • Publication number: 20240115155
    Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 11, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Amit LIMAYE, Keith KNAPP, Elizabeth NELSON, Patrick ALLEN, Amanda MASOTTA
  • Patent number: 11951288
    Abstract: A flush syringe for use in maintaining intravenous catheters, wherein the flush syringe can more efficiently and effectively flush the catheters by providing a pulsating, pulsatile, and/or pulsative flow of fluid that can be produced using momentum of the fluid moving. A steady force applied to a plunger while flushing can provide the pulsating, pulsatile, and/or pulsative flow of the fluid to the catheters.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: April 9, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Bryan Bihlmaier
  • Patent number: 11951266
    Abstract: A catheter assembly may include a catheter adapter that includes a distal end, a proximal end, and an inner surface forming a lumen. The lumen may extend between the proximal end and the distal end. The catheter assembly may also include a cannula and a cannula hub. The cannula hub may include an outer portion disposed outside of the catheter adapter and an inner portion disposed within the catheter adapter. The cannula may extend distally from the inner portion. In response to the outer portion sliding proximally along an outer surface of the catheter adapter, the cannula may be withdrawn proximally into the catheter adapter. The outer portion may be configured to slide proximally to a locked position in which the cannula hub is locked with respect to the catheter adapter, and a distal tip of the cannula is disposed within the catheter adapter.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: April 9, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Toe Toe Naing, Yun Hui Wong, Kiat Jin Cheng
  • Patent number: 11951275
    Abstract: Packages comprising a film surrounding the sterile medical device are described and including a tear-enabling feature and a gripping feature enabling a user to use a finger, a thumb or an end of a tool to apply a sufficient tearing force to cause the tear-enabling feature to tear and move the first end of the package away from the second end of the package using only one hand and to expose the sterile medical device to be accessed for use. Also described are methods of packaging a sterile medical device.
    Type: Grant
    Filed: April 7, 2023
    Date of Patent: April 9, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Bhanupratapsingh Dharmendrasingh Thakore, Preetika Singh, Satyabhan Jat
  • Patent number: 11951280
    Abstract: Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: April 9, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Richard Savoie, Gary Searle
  • Patent number: 11953420
    Abstract: Light detection systems for measuring light (e.g., in a flow stream) are described. Light detection systems according to embodiments include a light scatter detector, a brightfield photodetector and an optical adjustment component configured to convey light to the light scatter detector and to the brightfield photodetector. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) and kits having a light scatter detector, a brightfield photodetector and a beam splitter component are also provided.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: April 9, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Jizuo Zou, Matthew Bahr, Eric D. Diebold
  • Publication number: 20240108808
    Abstract: Syringe assemblies are provided including a partially pre-filled syringe barrel and a plunger rod that incorporates one or more retention elements on the plunger rod that prevents solution from entering a non-sterile area of the syringe when the plunger rod is pulled back. Methods to manufacture a sterilized partially-filled pre-fill syringe assembly are also disclosed.
    Type: Application
    Filed: December 14, 2023
    Publication date: April 4, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Paul P. Marici, Xiaoyu Sun, Jonathan Marek Zalot, Youstina Matta
  • Publication number: 20240110551
    Abstract: A hard seal, positive displacement pump is provided which may be included within a fluid delivery system. The pump includes a housing, a sleeve disposed radially within the housing, and a piston disposed radially within the sleeve. An outer shape of a first end of the sleeve contacts a correspondingly-shaped inner shape of a first end of the housing, thereby sealing the first end of the sleeve within the first end of the housing. The piston is radially and axially moveable within the sleeve, and an axially-reciprocating motion of the piston within the sleeve opens and closes a pump chamber defined between a first end of the piston and a first end of the sleeve.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 4, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro E. PIZZOCHERO, Mark WOOD
  • Patent number: 11944783
    Abstract: An injection monitoring device includes a syringe having a barrel configured to contain a medicament and a plunger configured to be displaced linearly into the interior of the barrel to dispense the medicament, a flange positioned between a proximal end and a distal end of the injection monitoring device and configured to be gripped during performance of the injection, and one or more force sensors positioned to detect data associated with an amount of force applied to the injection monitoring device during performance of an injection.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: April 2, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Mircea Stefan Despa, Adam Martin
  • Patent number: 11944434
    Abstract: A container assembly is disclosed including an outer container, a hollow inner member, and a closure. The outer container has a closed bottom, an open top, and a sidewall extending therebetween. The hollow inner member is disposed within the outer container and has an inner surface defining at least one capillary channel. The inner member includes a first end adjacent to the open top of the outer container and has an outer periphery seated against the sidewall of the outer container. The closure has a proximal end and a distal end. The closure proximal end is seated at least partially within the first end of the inner member to seal the outer container and inner member and define a fluid collection chamber. The closure distal end defines a recessed area shaped to direct fluid under capillary action to the at least one capillary channel in the inner member.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: April 2, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Benjamin R. Bartfeld, Bradley M. Wilkinson, Ajit Dastane
  • Patent number: 11946865
    Abstract: Systems and methods for optimizing detection of optical signals indicating the presence of an analyte of interest in a blood sample are described. In one aspect, a blood culture test vial having a sensor is inoculated with the blood sample, light at an excitation frequency of the sensor is transmitted to the test vial, an intensity of a plurality of fluorescence signals emitted from the test vial is measured, and the plurality of measured fluorescence signals are normalized using by a reference signal that is not dependent on a measured intensity of a fluorescence signal emitted from the test vial. In another aspect, a measurement system measures fluorescence signals from one or more reference vials performing in extreme pH conditions. Fluorescence signals emitted from test vials inoculated with samples under test are measured and compared to the signals measured from the one or more reference vials to address or mitigate variability in hardware components of the measurement system.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: April 2, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: James R. Petisce, Robert E. Armstrong, David J. Turner
  • Patent number: 11944792
    Abstract: Flush syringe assemblies are described herein. Such flush syringe assembly may include a barrel including a side wall defining a chamber, a collar mounted on a distal wall of the barrel and surrounding an elongate tip. A cap may be attached to the collar via a hinge. The flush syringe assembly may also include a cap attached to the collar via a hinge. A ring may be disposed around the collar with a locking element that engages with a corresponding mating locking projection on the cap. The cap may include a slanted surface. The slanted surface of the cap may include one or more ribs made of an elastomeric material.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: April 2, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Roza Mahmoodian
  • Patent number: 11946095
    Abstract: Disclosed herein are methods, compositions, and kits for barcoding nucleic acids. For example, particles for barcoding are provided, where the particle comprises: a first plurality of oligonucleotide barcodes each comprising a target-binding region, and a second plurality of oligonucleotides each comprising a target-specific target-binding region.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: April 2, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Gretchen Yinbon Lam, Eleen Shum
  • Publication number: 20240100251
    Abstract: An infusion set includes a base (221) and a flexible catheter (242) movable from a first catheter position disposed substantially entirely within the base (221) to a second catheter position in which a free end of the catheter (242) is disposed externally of the base (221). An introducer needle (234) is located within the catheter (242) and is movable between a first introducer needle position disposed substantially entirely within the base (221) and a second introducer needle position in which a free end of the introducer needle (234) is disposed externally of the base (221). A spring (281) is activated to move the catheter (242) from the first to the second catheter position and the introducer needle (234) from the first to the second introducer needle position to facilitate insertion of the catheter (242).
    Type: Application
    Filed: December 4, 2023
    Publication date: March 28, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Cole CONSTANTINEAU, Ryan SCHOONMAKER, Azadeh KHANICHEH, Michel BRUEHWILER, Judy WALISH
  • Publication number: 20240100252
    Abstract: A medicament delivery system (1) and method for determining an occlusion comprising a reservoir (4) that carries a medicament, a pump (3) connected to the reservoir (4) that draws the medicament out of the reservoir (4) for medication delivery, and an occlusion sensor (600) connected to the reservoir (4) that senses whether an occlusion is present wherein the occlusion sensor (600) is secured to an outer surface of the reservoir (4), the occlusion sensor (600) provides resistance output (630) to control electronics (8), and the control electronics (8) determines whether an occlusion is present based on the resistance output (630). The occlusion sensor (600) can be a strain gauge bonded onto a mid-section of an outer surface of a flexible reservoir (4) to provide a sensitive strain reading.
    Type: Application
    Filed: December 30, 2021
    Publication date: March 28, 2024
    Applicant: Becton, Dickinson and Company
    Inventor: John TUOHY
  • Patent number: 11940369
    Abstract: Aspects of the disclosure include a system for performing cytometry that can be operated in three operational modes. In one operational mode, a fluorescence image of a sample is obtained by exciting one or more fluorophore(s) with a top-hat-shaped excitation beam with a plurality of beams that are radiofrequency shifted relative to one another. In another operational mode, a sample can be illuminated successively over a time interval by a laser beam at a plurality of excitation frequencies in a scanning fashion to generate an image of the sample from the detected fluorescence. In another operational mode, the system can be operated to illuminate a plurality of locations of a sample concurrently by a single excitation frequency (e.g., a horizontal extent), which is generated, e.g., by shifting the central frequency of a laser beam by a radiofrequency and detected fluorescence is used to analyze the sample.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: March 26, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Eric D. Diebold, Keegan Owsley, Jonathan Lin
  • Patent number: 11940456
    Abstract: An automated apparatus can provide pre-analytical processing of samples, racking and forwarding to an adjacent analyzer for analysis. The apparatus may have a controller that implements an auto-learn process to teach robotic handlers the locations within the workspace(s) of the apparatus. A robotic sample handler may include a sensor configured to generate a detection signal when in a near vicinity of a fiducial beacon in the workspace of the apparatus for biological sample preparation, preprocessing and/or diagnostic assay performed by one or more analyzers of the automated apparatus. The controller may control the robotic sample handler to conduct a search pattern so that a location of the fiducial beacon may be detected and thereafter calculated to obtain a more accurate location of the beacon. The calculated positions may then serve as a basis for the controlled movement of samples by the robot to and from locations of the workspace.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: March 26, 2024
    Assignee: BECTON DICKINSON AND COMPANY
    Inventors: Christopher John Tesluk, Kevin Bailey, Matthew Wesly, John Moore
  • Patent number: 11940372
    Abstract: Aspects of the present disclosure include a method for sorting cells of a sample based on an image of a cell in a flow stream. Methods according to certain embodiments include detecting light from a sample having cells in a flow stream, generating an image mask of a cell from the sample and sorting the cell based on the generated image mask. Systems having a processor with memory operably coupled to the processor having instructions stored thereon, which when executed by the processor, cause the processor to generate an image mask of a cell in a sample in a flow stream and to sort the cell based on the generated image mask are also described. Integrated circuit devices (e.g., field programmable gate arrays) having programming for generating an image mask and for determining one or more features of the cell are also provided.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: March 26, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Jonathan Lin, Matthew Bahr, Keegan Owsley