Abstract: A system for infusing a gas into a vascular access device may include a catheter interface, which may include a distal end, a proximal end, and a lumen extending between the distal end and the proximal end. The system may also include a connector disposed on an outer surface of the catheter interface. The connector may be configured to couple to a reservoir. The reservoir may include a housing, which may include an opening and an impermeable wall. The opening may be configured to couple to the connector of the catheter interface. The reservoir may also include a molecular precursor to a gaseous agent that is suspended in a hydrogel and disposed within the housing. The gaseous agent may be antimicrobial, antithrombogenic, or both antimicrobial and antithrombogenic.

Abstract: Devices and methods detect an empty reservoir condition in an infusion pump using pump measurements such as motor current during aspiration. An infusion pump obtains and analyzes pump measurements indicative of pressure during aspiration and determines whether pump measurements satisfy metrics corresponding to an empty reservoir condition such as pressure threshold corresponding to a pump measurement value exceeded when the reservoir is empty, a range of pump measurement values indicating a pressure above normal operating pressure of the pump, and a designated shape of a signal waveform corresponding to the pump measurements indicating a pressure above normal operating pressure of the pump. Devices and methods can be configured to disregard one or more of the pump measurements obtained during one or more portions of the duration of the aspirate operation characterized by transient increases therein from normal operation of the pumping mechanism.

Abstract: A single use delivery device is disclosed having a manually deformable liquid container defining an inner chamber, the container having a distal end, a body, a proximal end, and an outlet on the distal end; a tip projecting from the outlet on the distal end of the container, the tip in fluid communication with the inner chamber of the container; a primer element for removing one or more air bubbles from the chamber, said primer element being attached to and in fluid communication with the deformable container, the container, the tip and the primer element being collapsible to minimize dead space in the delivery device; and two or more one-way valves. A method of administering a fluid to or flushing a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.

Abstract: Aspects of the present disclosure include a particle sorter with a droplet deflector configured to apply a known offset deflection force to a droplet stream. Particle sorters according to certain embodiments include a flow cell, a light source, e.g., laser, for irradiating an interrogation point of the flow cell, a detector for detecting light from the interrogation point, a droplet generator for producing a droplet stream from fluid exiting the flow cell and a droplet deflector configured to apply a known offset deflection force to the droplet stream. In some cases, the droplet deflector comprises first and second plates configured to be offset from one another. Methods and particle sorting modules for applying a known offset deflection force are also provided.

Abstract: In a computer; a computer readable medium for providing rapid syndrome analysis includes instructions for measuring a plurality of CUSUMs simultaneously and generating CUSUM data in response to an observed value. It also includes instructions for comparing the CUSUM data with a predetermined plurality of threshold values and instructions for generating a signal when the CUMSUM data exceeds any of the plurality of threshold values by a predetermined amount.

Abstract: An intravenous catheter device can include a safety mechanism having a slider that couples to a catheter adapter and slides relative to a barrel. A needle hub can be contained within the barrel and can be retracted once a catheter has been inserted into the patient's vasculature. The retraction of the needle hub can be triggered by the sliding of the slider. The slider may also function to guard the distal tip of the needle once the needle hub is retracted within the barrel.

Abstract: A pediatric catheter system may include a catheter adapter having a distal end, a proximal end, and a lumen extending therebetween. The lumen may include an upper surface and a lower surface with an adhesive coupled to the lower surface. The system may include a plurality of wings that extend outwardly from the catheter adapter. The plurality of wings may be configured to fold upwardly. The system may include a catheter cannula extending distally from the catheter adapter. The system may include a needle hub removably coupled to a proximal end of the catheter adapter and an introducer needle extending through the catheter tube. A proximal end of the introducer needle may be secured within the needle hub.

Abstract: The disclosure provides a system and method to safely and efficiently store and transport process tubes in a carrier tray comprising prior to and during amplification of nucleotides in the process tubes. The process tube disclosed includes a securement region having an annular ledge, a neck, and a protrusion. The securement region of the process tube can secure the process tube in a port of the carrier tray, but still allows the process tube to adjust or float in order to align the process tube into a rigid heater well of a thermal cycler.

Abstract: Devices and methods are provided to improve accuracy of occlusion detection based on measured data in a fluid delivery device by using dead band normalization of loaded measured data to unloaded measured data. The loaded measured data and unloaded measured data are obtained during the same fluid movement operation or stroke of the fluid delivery device. The dead band normalization can be performed during an aspiration operation or a dispensing operation. An interface in the fluid delivery device that is close to the fluid driving mechanism and that can at least temporarily move under control but without moving fluid can be used to identify when to generate unloaded measured data during a fluid movement operation for dead band normalization of loaded measured data measured during that fluid movement operation.

Abstract: A drug delivery system for injecting a medicament includes a housing, a container configured to receive a medicament including a stopper configured to move within the container and a closure, a needle in fluid communication with the container, a spacer configured to be engaged with the stopper, a first plunger, a first spring configured to bias the first plunger in an axial direction, second plunger disposed about the first plunger, a second spring configured to bias the second plunger in an axial direction. The first plunger is configured to move the spacer and the container relative to the housing via the first spring to establish fluid communication between the container and the patient needle, and the second plunger is configured to move the spacer and the stopper relative to the container via the second spring.

Abstract: Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of analytes of interest, including hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection device provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The collection device also includes a test strip, and provides a closed fluid transfer mechanism to transfer the collected fluid from the swab to the test strip while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.

Abstract: A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system.

Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.

Abstract: A disinfection tip is described for disinfecting a threaded connector of a syringe.

Abstract: A method to manage flushing of a catheter assembly may include providing a clamp for a fluid tube configured to be coupled to the catheter assembly. The clamp may include a sensor configured to detect the clamp is closed. The method may include starting a timer in response to the sensor detecting the clamp is closed. The method may include providing an alert in response to the timer reaching a predetermined duration of time. The alert may indicate to a clinician that the catheter assembly should be opened and flushed, which may prevent occlusion of the catheter assembly.

Abstract: An intravenous therapy system may include a housing to house an actuation hub, the actuation hub comprising; a needle hub operatively coupled to a needle to insert the needle into a patient's body; and a catheter hub operatively coupled to a catheter to insert the catheter into a patient's body, the catheter being formed coaxially with an outer surface of the needle; and an inflatable bladder formed along a length of the catheter to maintain the catheter in the patient's body.

Abstract: An ultrasonic echogenic device (100) includes a base layer (1), an echogenic layer (2) covering the base layer (1) and adhered to the base layer (1) at least by a separate lower adhesive (4), an outer layer (3) covering the echogenic layer (2) and adhered to the echogenic layer (2) at least by a separate upper adhesive (5), wherein the ultrasonic echogenic device (100) is configured such that a rough interface is provided at a position where the echogenic material of the echogenic layer (2) contacts at least the upper surface of the upper adhesive (5) and the lower adhesive (4), and the outer surface of the outer layer (3) at least partially follows an undulation of the rough interface. An ultrasonic echogenic device (100) with a simple structure and easily formed is obtained.

Abstract: A blood sample collection system, may include a housing, the housing including a blood collection port; and a baffle chamber; a needle formed through the housing and into the blood collection port; and a baffle formed within the baffle chamber to counteract a vacuum within a blood collection tube when pierced by the needle.

Abstract: Packages comprising a film surrounding the sterile medical device are described and including a tear-enabling feature and a gripping feature enabling a user to use a finger, a thumb or an end of a tool to apply a sufficient tearing force to cause the tear-enabling feature to tear and move the first end of the package away from the second end of the package using only one hand and to expose the sterile medical device to be accessed for use. Also described are methods of packaging a sterile medical device.