Abstract: A syringe assembly includes a syringe barrel having a first end, a second end, and a sidewall extending between the first end and the second end. The syringe assembly further includes a stopper disposed within a chamber of the syringe barrel, a plunger adapter engaged with the stopper and defining a recessed portion therein, and first and second plunger arms each having a first end pivotally secured to the plunger adapter. The first and second plunger arms each have a pre-use position where the plunger arms are spaced from each other, and a use position where the plunger arms are positioned adjacent to each other and configured to displace the stopper relative to the syringe barrel. The recessed portion of the plunger adapter receives a portion of a first end of a plunger rod when the first and second plunger arms are in the pre-use position and the use position.

Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.

Abstract: A packaging including a grouping nest for receiving syringes, a packaging tub, and a sealing cover for sealing the packaging tub. The packaging includes a plate intended to be positioned close to the flanges of the syringes before sealing of the tub; this plate includes a plurality of first surfaces intended to be placed in contact with the flanges and a plurality of second surfaces located on the side of the cover plate opposite this plurality of first surfaces, the distance between the plurality of first surfaces and the plurality of second surfaces being chosen in such a way that, when the plurality of first surfaces lies against the flanges, the plurality of second surfaces is in contact or in close proximity to the sealing cover.

Abstract: The present invention pertains to a stackable packaging unit (1) for the packaging of products (100), the said packaging unit (1) comprising at least one encircling wall (2) provided at least with a corner ridge (3) dividing it into at least two retaining panels (2a) Partially folded down towards one another about the said corner ridge (3) so as to hold the said products (100) to be packaged, at least one end of the said corner ridge (3) being connected to the corresponding edges of the said retaining panels (2a) by at least one inclined centring profile. The stackable packaging unit (1) also comprises an intermediate element. The invention also pertains to a packaging comprising at least one such packaging unit (1).

Abstract: The present invention relates to a container comprising: a body; a pusher movable with respect to the body between an initial position and an end-of-use position; a locker located on the pusher and forming an abutment so as to be able to abut against the body between the initial position and the end-of-use position, wherein, the abutment abuts against the body to limit distal movement of the pusher relative to the body to a pusher locking position located between the initial position and the end-of-use position; a locking arrangement capable of, temporarily, locking the locker on the pusher so as to define a locker locking position of the locker on the pusher, the locker locking position establishing the position of the abutment relative to the pusher so as to set the pusher locking position; and, an unlocking arrangement designed so that, with triggering, the locking arrangement is released so as to allow the locker to be displaced relative to the pusher and for the pusher to be moved past the pusher locking

Abstract: A syringe assembly includes a syringe barrel defining a chamber, a stopper disposed within the chamber, and a plunger assembly. The plunger assembly includes an elongated plunger rod, a housing, and a handle portion connecting the plunger rod and housing. The plunger assembly transitions from a first position disposed about the syringe barrel, to a second position with the plunger rod engaged with the stopper. Transition of the plunger assembly includes rotational engagement of the plunger rod and stopper.

Abstract: The present invention relates to an injection device (1) comprising:—a body (3) designed to receive a product to be injected, furnished at its distal end with an injection needle (7) and receiving a piston (5) capable of being moved between a storage position and an end-of-injection position under the effect of a distal pressure exerted on a piston rod (8) to the distal end of which it is attached,—means of protecting the injection needle (7) capable of adopting an initial position, during which the injection needle (7) is uncovered, and a final position, in which the said injection needle (7) is covered,—biasing means (26) aiming at moving the said covering element (6) from its initial position to its final position,—immobilization means (16, 31) aiming at keeping the said covering element (6) in its initial position, the said injection device (1) being characterized in that:—the said piston rod (8) comprises at least a first portion (9) and at least one second portion (10) coupled to the said piston (8), th

Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.

Abstract: Described herein are pharmaceutical packaging systems which prevent oxidative degradation of oxygen-sensitive drugs, such systems including a primary packaging container with an oxygen permeable component, a secondary packaging with very low permeability to oxygen and an oxygen absorber.

Abstract: The present invention relates to an injection assistance device including a body with a needle, grasping arrangement and first elastic return arrangement to dampen limited movement of the grasping arrangement, in at least one of the two directions, respectively distal or proximal, during an injection phase, and to maintain the body in its insertion position and the needle at a constant insertion length during the injection step, when the user increases, respectively releases, a distal pressure on the grasping arrangement. The invention also relates to an injection set including an injection device and the assistance device.

Abstract: Medical devices comprising a syringe barrel and a two-piece plunger rod are provided. According to one or more embodiments, the two-piece plunger rod includes a distal portion and proximal portion slidably mounted to the distal portion. The distal and proximal portions include a tab and plurality of grooves which engage to adjust the overall length of the plunger rod to a plurality of locked lengths. The locked lengths of the plunger rod permit varying amount of fluid to be expelled from the barrel.

Abstract: This packaging includes a grouping nest, a first tub, and a sealing cover. Lateral walls of the first tub are sloped to allow a nesting of this first tub in a second identical tub; the first tub includes recesses on the outer side of the tub forming tub and/or nest supporting pillars on the inner side of each wall, and having a tub and/or nest supporting surface opposite the bottom of the tub. The positioning of the recess forming a tub supporting pillar on one opposed lateral wall is different from the positioning of the recess forming a tub supporting pillar on the other opposed lateral wall allowing nesting of this first tub into a second identical tub in a first relative position of the first tub, while allowing the stacking of said first and second tubs one onto the other in a second relative position of the first tub.

Abstract: The invention relates to a protection device (10) for a needle of an assembly or of an injection device having a hub portion provided with a needle, the said protection device (10) comprising: an outer casing (20) formed of a first material; and an inner casing (30) formed of a second material different from the said first material and defining a cavity (32) for receiving in a sealing way at least the hub portion, said cavity (32) having an inner wall (34); attachment means (40) defined in the said cavity (32) to removably engage and secure said protection device (10) at least along a sealing line to the injection device; the protection device being characterized in that it further comprises aspiration limiting means (40, 50) for limiting the deformation of said cavity (32) when said protection device (10) is separated from the assembly or the injection device.

Abstract: A syringe assembly includes a syringe barrel defining a chamber and having a stopper disposed within the chamber, a sleeve having a first end and a second end and extending at least partially about the syringe barrel, and a cap associated with a second end of the sleeve. The syringe assembly also includes a plunger rod having a first end associated with the cap and a second end, wherein the plunger rod is transitionable from a pre-use position, in which at least a portion of the second end of the plunger rod extends along a portion of a barrel sidewall, to a ready-to-use position in which the plunger rod is aligned with the stopper. Upon proximal movement of the sleeve in a direction away from a first end of the barrel, the plunger rod is configured for lateral movement with respect to the cap into the ready-to-use position.

Abstract: Packaging for medical containers, including a tub having a peripheral wall, a sealing cover sealable on an opening of the tub and a sealing envelope able to protect the sealing cover. The sealing envelope includes: a lower sealing part, having a frame able to be sealed to the peripheral wall of the tub, and a bonding surface that extends outwards from the frame, and an upper sealing part sealed on the bonding surface to enclose the opening of the tub and the sealing cover.

Abstract: A syringe assembly includes a syringe barrel having an exterior surface, an inside surface defining a chamber, an open proximal end, a distal end, and an outlet disposed adjacent the distal end in fluid communication with the chamber; and a plunger assembly disposed at least partially within the syringe barrel. The plunger assembly includes an elongated plunger rod and a plunger head. The elongated plunger rod is associated with the plunger head to move the plunger head within the chamber of the syringe barrel through an injection cycle. The plunger rod is adapted to move from a collapsed position extending alongside the exterior surface of the syringe barrel to an extended position engaging the plunger head to move the plunger head through the injection cycle.

Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.