Abstract: According to the invention, first and second locking means (16, 12) are conformed to engage with each other and to permit the locking of an activation means (4) in at least one intermediate position between first and second positions of the activation means (4). The first and second locking means (12, 16) are conformed to be disengaged from each other when the protection member (3) is in a first position, in which a movement of a vessel contained in the device (1) is possible from an initial position to a position for inserting a needle contained in the vessel, and to be engaged with each other when the protection member (3) leaves said first position.

Abstract: The packing according to the invention comprises: a container for holding said at least one object to be sterilized, having an inlet opening and a discharge opening via which said at least one object may pass into and out of said container, said container comprising a rigid part which comprises a peripheral wall bored with a multitude of small holes having dimensions smaller than those of the said at least one object, and a non-rigid part in a material porous to the sterilization fluid and non-porous to microbial contamination, this non-rigid part being able to contain said rigid part and to be sealed thereon; and at least one envelope made in a flexible and airtight material, which is vacuum sealing fitted on said container.

Abstract: Method of identifying a container (1) obtained by a process comprising the following steps: (A) starting from a blank (2) of the container (1), at least part of the said container (1) is formed; (B) a two-dimensional or three-dimensional marking zone (4), the temperature of which is maintained at a value below the glass transformation temperature of the constituent substrate, is provided in or on the substrate of the blank (2) and, in the said marking zone (4), an identification code (5) is reproduced by illumination (6) of the said marking zone (4) with at least one beam (7) of coherent monochromatic localized electromagnetic radiation to which the substrate is at least partially transparent, the said beam (7) being operated and controlled in order to remove or modify the constituent substrate of the wall (3) and to leave the identification code (5), in positive or negative form, in the said wall so that the said code is readable; and (C) at least the said marking zone (4) is annealed so as at least to reduc

Abstract: A medical device for the injection of a product. The device includes a body receiving an injection needle and a container containing the product to be injected; an arrangement for holding the needle in an injection position; an arrangement for holding the container in a position permitting injection; and, a piston engaged in the container. The device also includes first and second actuators which make it possible, at the end of the injection, to respectively release the arrangement for holding the needle before, or simultaneously to, the release of the arrangement for holding the container. A container support is mounted slidably on the body and is displaceable relative to the latter in order to perform the injection. The container support is held in a standby position before injection with the needle being held in the injection position.

Abstract: A prefilled ready-to-use syringe, including a tubular body having, at its distal end, a tip to take a needle and, at its proximal end, a flange, a piston able to slide inside the tubular body and defining, with the tubular body, an internal working volume at least partially filled with a liquid, a rod for actuating the piston extending beyond the proximal end of the tubular body, characterized in that a rigid cover is attached and fixed in a definitive way to the flange and has a central opening for the free translational passage of the actuating rod, and the said cover forms a stop for the actuating rod in the proximal direction, and a plug is arranged to translate freely in the tubular body between the piston and the proximal end of the body, the plug being resistant to puncturing with a needle.

Abstract: The present invention relates to an injection device (1) comprising: —a container (5) receiving a product, and provided with an injection needle (6), —a housing (9, 11) receiving said container, said container being movable relative to said housing between an initial position, an insertion position, and a final position, —retaining means (12, 15), for maintaining said container in said insertion position, —deactivating means (20), for releasing said retaining means, said device being characterized in that it comprises: —temporizing means (19, 26, 27), for controlling the release of said retaining means until substantially all of the product contained within said container has passed through said injection needle before said container moves to said final position, and —a needle shield (2) coupled with said housing (9, 11) removal of said needle shield being with limited or no rotation of said needle shield. The invention also concerns a kit comprising such a device.

Abstract: The present invention relates to an injection device (1) comprising:—a body (3) designed to receive a product to be injected, furnished at its distal end with an injection needle (7) and receiving a piston (5) capable of being moved between a storage position and an end-of-injection position under the effect of a distal pressure exerted on a piston rod (8) to the distal end of which it is attached,—means of protecting the injection needle (7) capable of adopting an initial position, during which the injection needle (7) is uncovered, and a final position, in which the said injection needle (7) is covered,—biasing means (26) aiming at moving the said covering element (6) from its initial position to its final position,—immobilization means (16, 31) aiming at keeping the said covering element (6) in its initial position, the said injection device (1) being characterized in that:—the said piston rod (8) comprises at least a first portion (9) and at least one second portion (10) coupled to the said piston (8), th

Abstract: An assembly for oral administration of a medicinal product to be reconstituted from an active principle in dry or liquid form and from a diluent, A device including a prefilled syringe with said diluent, able by itself to receive a parenteral injection member is provided. A support including a body of elongate form is fastened to the syringe, the support includes a device for fixing to the syringe and, at its distal end a device for preventing the connecting of the needle to the tip of the syringe. A bottle including the active principle and a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe, the transfer system being separate from the support.

Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.

Abstract: A pre-filled syringe assembly having a tamper evident tip cap is provided for indicating if the contents of the syringe assembly have been compromised. The syringe barrel has an interior chamber which defines a pressure therein and is sealed at the proximal and distal ends by a first and second seal, respectively, to maintain this pressure. The second seal is formed of a deformable material and a tip cap is located about the second seal and distal end of the syringe barrel. This tip cap includes a viewable indicator representing a change in state of the syringe contents. The indicator has a portion positioned in contact with the second seal such that the first distinguishing feature is viewable through a portion of the cap. Tampering of the contents within the interior chamber causes a change in pressure and movement of the indicator indicating tampering of the syringe assembly.

Abstract: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to the profile of the syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of the contents of the syringe barrel.

Abstract: A syringe assembly includes a syringe barrel having an exterior surface, an inside surface defining a chamber, an open proximal end, a distal end, and an outlet disposed adjacent the distal end in fluid communication with the chamber; and a plunger assembly disposed at least partially within the syringe barrel. The plunger assembly includes an elongated plunger rod and a plunger head. The elongated plunger rod is associated with the plunger head to move the plunger head within the chamber of the syringe barrel through an injection cycle. The plunger rod is adapted to move from a collapsed position extending alongside the exterior surface of the syringe barrel to an extended position engaging the plunger head to move the plunger head through the injection cycle.

Abstract: The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel the contents thereof.

Abstract: The present invention relates to a needle assembly (1) to be used in combination with a storing device (200) comprising a barrel (8) defining a chamber (9) receiving a product (4) and a piston (2), the assembly (1) comprising: —needle-bearing portion (7) in a first material, movable between an exposed and a retracted positions of the needle (5), —engaging means (8a, 10, 11, 18,) for securing said needle-bearing portion (7) to said barrel (8) in the exposed position, characterized in that it comprises: —sealing means (15) in a second material for tightly sealing the distal end (9a) of said chamber (9) to said needle-bearing portion (7), —a breakable portion (7a) located between said engaging means (8a, 10, 11, 18,) and said needle-bearing portion (7), which, when broken, allows independent proximal displacement of said needle-bearing portion (7) relative to said engaging means (8a, 10, 11, 18,) between said exposed and said retracted positions, said first material being more rigid than said second material.

Abstract: The present invention relates to a shield (10) for the distal extremity of an administration device (3) comprising a hub (2) on which said shield (10) is to be removably engaged, said shield (10) having a wall (13) the internal face (14) of which defining an interior cavity (15) for receiving the extremity of the administration device (3), at least a portion (14a) of said internal face (14) being intended to be in contact with said hub (2) when said shield (10) is engaged on the extremity of said administration device (3), whereby said portion (14a) has, distributed over a major portion of said portion (14a), a surface feature (16, 17) that defines the amount of contact between said portion (14a) and said hub (2).

Abstract: The invention relates to an automatic injection device (1) for a product contained in a container (50), comprising: a housing (8, 19) receiving the container (50), the container being movable between an initial position and an insertion position, triggering means (23) for initiating the movement of said container (50) from its initial position to its insertion position, said triggering means (23) being in one of a passive state, in which application of a force on said triggering means does not initiate movement of said container (50), and an active state, in which application of said force on said triggering means does initiate said movement, and a safety shield (10) movable with respect to said housing (8, 19) between a first position and a second position, movement of said safety shield (10) from its first position to its second position placing said triggering means (23) in its active state, characterized in that said device comprises: an indicator (19c, 13) that provides an indication to a user of the dev

Abstract: The invention relates to an automatic injection device (1) comprising: a container (6) provided with a needle (8); a housing (3) receiving a container (6) movable relative to said housing (3) between an initial position to an insertion position; a needle shield (12) for receiving said needle (8) and in which the needle (8) is embedded prior to use of said device (1); a deshielder (33) coupled to said needle shield (12) by first connecting means (51) and removably assembled to the distal part of the housing (3) by second connecting means (44, 45a, 45b, 57), characterized in that: said first and second connecting means are designed so that a rotational movement of the deshielder (33) about the device axis (2) of the device (1) with respect to the housing (3) causes an axial displacement of the needle shield (12) in the distal direction with substantially no rotational movement of the needle shield (12) with respect to the needle (8).

Abstract: The invention relates to a device (1) for automatic injection of a product into an injection site, said device (1) further comprising a needle (6) and a needle shield (2) for protection of said needle (6) prior to use of said device, and a housing (300) receiving the container (50) and a deshielder (8) for removing said needle shield (2) from said device (1), said deshielder (8) being coupled to said needle shield (2) and being mounted on the housing (300) in a separable manner, for example through breakable or snap-fit means, said deshielder (8) comprising tamper evidence means that are activated by the removal of at least one part of said deshielder (8). Said at least one part of said deshielder (8) can be removed from the housing (300) by exerting a traction force equal or less to 30 N.