Abstract: The present invention concerns methods for multiplication of viruses in cell culture in which cells are infected with a virus and after infection the cells are cultured in cell culture under conditions that permit multiplication of the viruses and at the same time targeted additional, at least two-fold, multiplication of the cells. The invention also concerns the use of the viruses so obtained or proteins expressed by them for production of drugs and diagnostic agents.
Type:
Application
Filed:
September 11, 2002
Publication date:
June 2, 2005
Applicant:
CHIRON BEHRING GMBH & CO.
Inventors:
Jurgen Vorlop, Christian Frech, Holger Lubben, Jens-Peter Gregersen
Abstract: In order to produce a sawing machine including a plurality of drives and a control unit which is constructed in a simple manner in regard to the control of the drive system, it is proposed that a first drive and a second drive be controlled in such a manner that they are not operable at the same time and that the first drive and the second drive be coupled to a common frequency converter.
Abstract: The invention relates to a two-component system for the treatment and prophylaxis of sepsis and of septic shock, where the components are intended to act in combination with each other, to a pharmaceutical and a packaging unit containing both the components, and to a process for their preparation.
Abstract: An adenoviral transfer vector for the gene transport of a DNA sequence, which is produced from an adenoviral plasmid which no longer expresses any natural adenoviral proteins and comprises
Abstract: A stabilized protein preparation is described which contains no antithrombin III and is protected against loss of activity during pasteurization by the addition of stabilizers which comprise one or more saccharides as a mixture with more than 0.5 mol/l of one or more amino acids chosen from the group arginine, lysine, histidine, phenylalanine, tryptophan, tyrosine, aspartic acid and its salts or glutamic acid and its salts. Glycine and/or glutamine can also be additionally added to each of these amino acids. A process for the viral inactivation or viral depletion of a protein preparation of this type which contains the abovementioned stabilizers and is subjected to pasteurization or viral depletion by filtration, centrifugation or treatment with detergents or bactericidal or virucidal agents is also described.
Type:
Application
Filed:
May 7, 2001
Publication date:
December 13, 2001
Applicant:
AVENTIS BEHRING GMBH
Inventors:
Juergen Roemisch, Harald Stauss, Hans-Arnold Stoehr