Patents Assigned to Behrinwerke Aktiengesellschaft
  • Fusion proteins for prodrug activation
    Patent number: 7273727
    Abstract: The invention relates to compounds which contain an antigen binding region which is bound to at least one enzyme which is able to metabolize a compound (prodrug) which has little or no cytotoxicity to a cytotoxic compound (drug), where the antigen binding region is composed of a single polypeptide chain. It is advantageous for covalently bonded carbohydrates to be present on the polypeptide chain.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: September 25, 2007
    Assignee: Behrinwerke Aktiengesellschaft
    Inventors: Mathias Gehrmann, Gerhard Seeman, Klaus Bosslet, Jorg Czech