Patents Assigned to BEIJING DIAGREAT BIOTECHNOLOGIES CO., LTD.
  • Patent number: 11635426
    Abstract: A test strip and kit for testing mycophenolic acid and a preparation method of the test strip are described. The test strip includes a bottom plate and a sample pad, a glassfiber membrane, a nitrocellulose membrane and an absorbent paper which are successively lapped on a surface of the bottom plate, the sample pad is treated by a sample pad treatment fluid; the glassfiber membrane is treated by a glassfiber membrane treatment fluid; the glassfiber membrane is coated by a mycophenolic acid specific-antibody conjugate; the nitrocellulose membrane is provided with a detection line and a quality control line; and a mycophenolic acid protein conjugate is sprayed on the detection line.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: April 25, 2023
    Assignee: BEIJING DIAGREAT BIOTECHNOLOGIES CO., LTD.
    Inventors: Jianping Zhou, Yujun Zhou, Xiuli Xu
  • Patent number: 11237158
    Abstract: Some embodiments of the disclosure provide a time-resolved fluorescent immunochromatographic test strip for detecting paclitaxel drugs as well as a preparation method and application thereof. In some embodiments, the test strip includes a test paper and a sample diluent. The test paper includes a bottom plate, a sample absorption pad, a fluorescent microsphere pad, a bonding pad, and an absorbent pad. The sample absorption pad, the fluorescent microsphere pad, the bonding pad, and the absorbent pad are sequentially overlapped on the bottom plate. The fluorescent microsphere pad is sprayed with a fluorescent microsphere-labeled anti-paclitaxel monoclonal antibody. A detection area and a quality control area are immobilized on the bonding pad. The detection area is sprayed with a paclitaxel hapten-carrier protein conjugate. The quality control area is sprayed with a goat anti mouse antibody.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: February 1, 2022
    Assignee: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Xiuli Xu, Yanxin Wang, Yuanrong Chang, Jianping Zhou
  • Patent number: 11162959
    Abstract: Some embodiments of the disclosure provide a time-resolved fluorescent immunochromato-graphic test strip for detecting vancomycin as well as a preparation method and application thereof. In some embodiments, the test strip includes a bottom plate and a sample absorption pad. A fluorescent microsphere pad, a nitrocellulose membrane coated with a vancomycin-carrier protein conjugate, and an absorbent pad are sequentially overlapped and pasted on the bottom plate. The fluorescent microsphere pad is sprayed with a fluorescent microsphere-labeled vancomycin monoclonal antibody, and the vancomycin monoclonal antibody is prepared by using a vancomycin-bovine serum albumin conjugate as an immunogen.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: November 2, 2021
    Assignee: Beijing Diagreat Biotechnologies Co., LTD.
    Inventors: Xiuli Xu, Yanxin Wang, Yuanrong Chang, Jianping Zhou
  • Patent number: 11141732
    Abstract: A detection kit for quickly detecting a lead content lead a sample is provided, and belongs to the technical field of medical in vitro immunoassay. The kit includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The provided kit has advantages of having simple preprocessing, having no need of digestion, and being economic, fast and convenient, and the like, can realize storage at room temperature, a rapid speed, a high throughout, a low instrument cost, simple and convenient operations, single-person packaging, and detection at any time, which greatly improves the simplicity and convenience of clinical use.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: October 12, 2021
    Assignee: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping Zhou, Yanxin Wang, Yujun Zhou
  • Publication number: 20210094030
    Abstract: A detection kit for quickly detecting a lead content lead a sample is provided, and belongs to the technical field of medical in vitro immunoassay. The kit includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The provided kit has advantages of having simple preprocessing, having no need of digestion, and being economic, fast and convenient, and the like, can realize storage at room temperature, a rapid speed, a high throughout, a low instrument cost, simple and convenient operations, single-person packaging, and detection at any time, which greatly improves the simplicity and convenience of clinical use.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 1, 2021
    Applicant: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping Zhou, Yanxin Wang, Yujun Zhou
  • Publication number: 20210055288
    Abstract: The invention provides immunochromatographic test strips for detecting digoxin and uses thereof. The immunochromatographic test strips include a bottom plate, a sample pad, a glass fiber mat, a nitrocellulose membrane and a water absorbing paper that are sequentially overlapped on the bottom plate. The glass fiber mat is sprayed with a digoxin-specific antibody-fluorescent microsphere complex. The nitrocellulose membrane is sequentially provided with a detection line coated with digoxin protein conjugate and a quality control line coated with a secondary antibody. The digoxin-specific antibody-fluorescent microsphere complex is obtained by conjugation between a digoxin monoclonal antibody or a digoxin polyclonal antibody and a fluorescent microsphere. The digoxin protein conjugate includes a digoxin-conjugated rabbit albumin or a digoxin-conjugated rabbit ovalbumin. The test strips provided by the invention are low cost, provide simple and rapid use, and have excellent stability and high sensitivity.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 25, 2021
    Applicant: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping ZHOU, Yujun ZHOU, Xiuli XU
  • Publication number: 20210025880
    Abstract: A test strip and kit for testing mycophenolic acid and a preparation method of the test strip are described. The test strip includes a bottom plate and a sample pad, a glassfiber membrane, a nitrocellulose membrane and an absorbent paper which are successively lapped on a surface of the bottom plate, the sample pad is treated by a sample pad treatment fluid; the glassfiber membrane is treated by a glassfiber membrane treatment fluid; the glassfiber membrane is coated by a mycophenolic acid specific-antibody conjugate; the nitrocellulose membrane is provided with a detection line and a quality control line; and a mycophenolic acid protein conjugate is sprayed on the detection line.
    Type: Application
    Filed: August 30, 2019
    Publication date: January 28, 2021
    Applicant: BEIJING DIAGREAT BIOTECHNOLOGIES CO., LTD.
    Inventors: Jianping ZHOU, Yujun ZHOU, Xiuli XU