Patents Assigned to Beijing Harmony Health Medical Diagnostics Co., Ltd.
  • Patent number: 11747349
    Abstract: Provided is a method for simultaneously detecting Vitamin K1 and Vitamin K2 in traces of blood. The method includes: constructing a two-dimensional liquid chromatography-tandem mass spectrometer, establishing an analytical method, and detecting at least three mixed standard solutions using the constructed two-dimensional liquid chromatography-tandem mass spectrometer to obtain a first detection result; fitting standard curve equations respectively corresponding to Vitamin K1 and Vitamin K2; and mixing and centrifuging a blood sample to which an extraction reagent and a certain amount of internal standard substance are added, collecting a supernatant, blowing the supernatant to dry with nitrogen, redissolving the residue, and detecting the dry supernatant using the constructed two-dimensional liquid chromatography-tandem mass spectrometer to obtain a second detection result. In this manner, concentrations of Vitamin K1 and Vitamin K2 in the blood sample are obtained.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: September 5, 2023
    Assignee: Beijing Harmony Health Medical Diagnostics Co., Ltd.
    Inventors: Jinbao Zhao, Yongjuan Jia, Junjun Ni