Abstract: The present invention provided a simple three-step approach based on the combinational induction with activin A, all-trans retinoic acid and, optionally, other maturation factors which are able to induce embryonic stem cells to differentiate into insulin-producing cells. A kit used to induce embryonic stem cells to differentiate into insulin-producing cells was also provided.
Type:
Grant
Filed:
April 14, 2006
Date of Patent:
August 17, 2010
Assignee:
Beijing Hua Yuan Bo Chuang Technology Limited