Patents Assigned to Beijing Normal University
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Patent number: 12162904Abstract: A mannose derivative is an isonitrile-containing mannose derivative of formula (I), including different linking groups X: A radioactive preparation is provided, including a radiolabeled compound formed by radiolabeling the mannose derivative with a radionuclide. An application of the radioactive preparation in the diagnosis and treatment of tumors is also provided.Type: GrantFiled: November 17, 2023Date of Patent: December 10, 2024Assignee: Beijing Normal UniversityInventors: Junbo Zhang, Qing Ruan, Guangxing Yin, Xuebin Wang, Zhanbin Zhang, Zhigang Tang, Jie Lu
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Patent number: 11993686Abstract: The present application discloses a surface treatment method of a polymer for 5G, belonging to the technical field of surface treatment of polymer. By injecting and adding the oxygen elements to the polymer, the polymer matrix elements and the injected atoms can form a blend structure, which can increase the surface roughness of the polymer, improve its bonding strength with the metal, and thus enhance its anti-peel strength. The surface treatment method of the application has the surface resistivity, surface roughness, water absorption and tensile properties of the polymer all considered. The equipment used in the invention has long service life and low cost, and can realize large-scale roll-to-roll production. The method can be popularized in polymer surface treatment.Type: GrantFiled: July 20, 2020Date of Patent: May 28, 2024Assignees: Beijing Normal University, Guangdong Guangxin Ion Beam Technology Co., Ltd.Inventors: Bin Liao, Xiao Ouyang, Guoliang Wang, Xiaoping Ouyang, Jun Luo, Pan Pang, Lin Chen, Xu Zhang, Xianying Wu, Minju Ying
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Patent number: 11865194Abstract: Disclosed herein is a benzene ring-containing glucose derivative of formula (I): where R1 is each independently and R2 is hydrogen. This application also provides a radioactive drug, including a complex formed by the benzene ring-containing glucose derivative and a radionuclide. Use of the benzene ring-containing glucose derivative in the tumor treatment and diagnosis is further provided.Type: GrantFiled: April 7, 2023Date of Patent: January 9, 2024Assignee: Beijing Normal UniversityInventors: Junbo Zhang, Qianqian Gan, Qianna Wang, Xuran Zhang, Qing Ruan, Yuhao Jiang, Xuebin Wang, Zhigang Tang, Jie Lu, Zhanbin Zhang
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Patent number: 11801452Abstract: The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.Type: GrantFiled: October 22, 2021Date of Patent: October 31, 2023Assignee: Beijing Normal UniversityInventor: Shuyao Wen
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Publication number: 20230314545Abstract: Embodiments of the present disclosure disclose a measuring device of zenith angle, which relates to the technical field of angle measurement and is used to measure solar zenith angle. A light receiving member includes solar panels, a support frame with a regular pyramid structure, and a first counterweight member. Light intensity processing circuits are electrically connected to the solar panels and determine a rotation angle of the support frame based on intensity of light received by each solar panel; a direction adjusting member is electrically connected to the light intensity processing circuits to adjust angles of the support frame in both vertical direction and horizontal direction. The embodiments of the present disclosure have a simple structure, and can avoid limitations on placement angles of the device, measure a zenith angle quickly and accurately, reduce measurement costs, and be made into a small-sized device to facilitate outdoor carrying.Type: ApplicationFiled: March 21, 2023Publication date: October 5, 2023Applicant: Beijing Normal UniversityInventors: Yujun Yi, Kebing Chen
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Publication number: 20230190774Abstract: The present disclosure relates to, inter alia, a method of treating cancer in a human patient in need thereof, comprising administering a therapeutically effective amount of a substrate of AKR1B1, AKR1B10, or both to said patient, wherein said patient has, or is suspected to have, cancer cells with elevated levels of AKR1B1, AKR1B10, or both, wherein said substrate is not 2-deoxy-D-glucose.Type: ApplicationFiled: December 6, 2022Publication date: June 22, 2023Applicant: Beijing Normal University Hong Kong Baptist University United International CollegeInventors: Stephen Chung, Shiqing Zhang
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Patent number: 11538653Abstract: The present invention discloses an ion beam lithography method based on an ion beam lithography system. The ion beam lithography system includes a roll-roll printer placed in a vacuum, and a medium-high-energy wide-range ion source, a medium-low-energy wide-range ion source and a low-energy ion source installed on the roll-roll printer. The ion beam lithography method includes: first coating a polyimide (PI) substrate with a dry film, etching the dry film according to a preset circuit pattern, then using the ion beam lithography system to deposit a wide-energy-range metal ion on the circuit pattern to form a film substrate, and finally stripping the dry film off the film substrate to obtain a printed circuit board (PCB).Type: GrantFiled: May 26, 2020Date of Patent: December 27, 2022Assignee: Beijing Normal UniversityInventors: Bin Liao, Xiaoping Ouyang, Jun Luo, Xu Zhang, Lin Chen, Pan Pang, Xianying Wu, Minju Ying
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Patent number: 11524017Abstract: The present disclosure relates to, inter alia, a method of treating cancer in a human patient in need thereof, comprising administering a therapeutically effective amount of a substrate of AKR1B1, AKR1B10, or both to said patient, wherein said patient has, or is suspected to have, cancer cells with elevated levels of AKR1B1, AKR1B10, or both, wherein said substrate is not 2-deoxy-D-glucose.Type: GrantFiled: November 3, 2016Date of Patent: December 13, 2022Assignee: Beijing Normal University Hong Kong Baptist University United International CollegeInventors: Stephen Chung, Shiqing Zhang
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Patent number: 11373837Abstract: The disclosure provides a metal ion source emitting device comprising a ceramic chamber, a leading-out electrode chamber and three cathodes hermetically connected, a trigger electrode fixed on a ceramic insulating element, a cathode target material fixed on an indirect cooling channel, a limiting element fixed on a fixed element, the fixed element fixing the indirect cooling channel on a cathode cooling pipe, the cathode cooling pipe fixed on a cathode flange, a trigger binding post connected with the trigger electrode, a leading-out electrode and an accelerating electrode arranged right below a cathode in the leading-out electrode chamber, and leading-out slits formed on the accelerating electrode and the leading-out electrode. According to the emitting device, three cathodes can operate simultaneously with only one anode, increasing irradiation area of an ion source, and improving the operating efficiency and energy utilization rate, with a more compact emitting source and larger processing area.Type: GrantFiled: July 14, 2020Date of Patent: June 28, 2022Assignees: Beijing Normal University, GUANGXIN ION BEAM TECHNOLOGY CO., LTD.Inventors: Bin Liao, Xiao Ouyang, Guoliang Wang, Xiaoping Ouyang, Jun Luo, Pan Pang, Lin Chen, Xu Zhang, Xianying Wu, Minju Ying
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Publication number: 20220184521Abstract: A rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at once is provided. At least two distillation flasks are included. The distillation flasks are connected in sequence and rotated along the same axis. A bracket is disposed at the lower part between the distillation flasks for support. Instead of one rotation axis, at least two axes are included. Each rotation axis is provided with at least one distillation flask. The number of condensers and the number of collecting flasks increase correspondingly with the number of distillation flasks. If the number of distillation flasks on one rotation axis is greater than 1, a connector is disposed between the condenser and a transmitter. The collecting flask can be changed into a collector with the function of accurately quantitating and discharging distillates. Each distillation flask may be connected to a concentrated liquid quantitative assembly.Type: ApplicationFiled: March 7, 2022Publication date: June 16, 2022Applicant: Beijing Normal UniversityInventors: Shuyao Wen, Wenda Li
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Publication number: 20220040593Abstract: The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.Type: ApplicationFiled: October 22, 2021Publication date: February 10, 2022Applicant: Beijing Normal UniversityInventor: Shuyao Wen
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Patent number: 11189468Abstract: The present invention discloses a magnetic filter tube, and relates to the technical field of magnetic filters. The magnetic filter tube includes a first rectangular tube and a second rectangular tube, where one end of the first rectangular tube is fixedly connected to one end of the second rectangular tube; the other end of the first rectangular tube forms an inlet of the magnetic filter tube; the inlet of the magnetic filter tube is connected with a cathode target flange; the other end of the second rectangular tube forms an outlet of the magnetic filter tube; the outlet of the magnetic filter tube is connected with a vacuum chamber; an inner wall of the first rectangular tube and an inner wall of the second rectangular tube are each provided with a protrusion and a groove; the protrusion is filled with cold water.Type: GrantFiled: May 26, 2020Date of Patent: November 30, 2021Assignees: Beijing Normal University, Wenli (Guangdong) Technology Co., Ltd.Inventors: Bin Liao, Xiaoping Ouyang, Qingsong Hua, Jun Luo, Lin Chen, Xu Zhang, Xianying Wu, Pan Pang, Ran Han, Minju Ying, Weifeng He, Guangyu He
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Patent number: 11185791Abstract: The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.Type: GrantFiled: July 22, 2020Date of Patent: November 30, 2021Assignee: Beijing Normal UniversityInventor: Shuyao Wen
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Publication number: 20200346132Abstract: The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.Type: ApplicationFiled: July 22, 2020Publication date: November 5, 2020Applicant: Beijing Normal UniversityInventor: Shuyao Wen
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Publication number: 20200238268Abstract: The present invention discloses a CoFe2O4-WTRs composite magnetic catalyst for efficiently degrading atrazine by activating peroxymonosulfate, preparation method and application thereof. The CoFe2O4-WTRs composite magnetic catalyst is prepared by three steps: the first step is acid-leaching of WTRs, using the WTRs as iron source to provide the iron ions required for the synthesis of CoFe2O4; the second step is preparing of a precursor, synthesizing CoFe2O4 by chemical co-precipitation method and uniformly loading the prepared CoFe2O4 on the WTRs; and the third step is calcining the precursor to synthesize the CoFe2O4-WTRs composite magnetic catalyst. The catalytic performance of the CoFe2O4-WTRs composite magnetic catalyst prepared by the present invention is evaluated using PMS as an oxidant and atrazine as a target pollutant. The CoFe2O4-WTRs can efficiently remove atrazine from the actual water, exhibiting good potential for practical application.Type: ApplicationFiled: January 25, 2019Publication date: July 30, 2020Applicant: Beijing Normal UniversityInventors: Xiaowan LI, Xitao LIU, Chunye LIN, Huijuan ZHANG, Zhou ZHOU, Guoxuan FAN, Mengchang HE, Wei OUYANG
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Publication number: 20190091247Abstract: The present disclosure relates to, inter alia, a method of treating cancer in a human patient in need thereof, comprising administering a therapeutically effective amount of a substrate of AKR1B1, AKR1B10, or both to said patient, wherein said patient has, or is suspected to have, cancer cells with elevated levels of AKR1B1, AKR1B10, or both, wherein said substrate is not 2-deoxy-D-glucose.Type: ApplicationFiled: November 3, 2016Publication date: March 28, 2019Applicant: Beijing Normal University Hong Kong Baptist University United International CollegeInventors: Stephen Chung, Shiqing Zhang
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Patent number: 7026118Abstract: The present invention provides a pharmaceutical composition for treatment of mammal disease by regulating the immune system, which contains CaN B subunit and/or its functional derivant in effective amount for treating the disease.Type: GrantFiled: August 29, 1999Date of Patent: April 11, 2006Assignee: Beijing Normal UniversityInventors: Qun Wei, Mingshan Yan, Qinshan Gao, Guohua Jiang, Mulan Lian, Yan Chen
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Patent number: 5812631Abstract: A method for manufacturing the monolithic capillary X-ray lens, comprising the steps of Drawing a hollow glass raw-tube into monocapillaries in a heating furnace by a drawing tower; Stacking monocapillaries into a symmetric mould to form a multibundle; Feeding the multibundle into the heating furnace to be heated at uniform speed or variable speed; Drawing the multibundle by a drawing tower at uniform speed and variable speed to form a first integrated lens billet; Cutting the monolithic lens billet into desired shape according to usage to form said first monolithic capillary X-ray lens. A monolithic capillary X-ray lens produced by using said method comprises a plurality of X-ray channels passing from one end through another end, and is a single glass solid formed by melting together the walls themselves of said X-ray channels.Type: GrantFiled: February 14, 1997Date of Patent: September 22, 1998Assignee: China Aerospace Corporation and Beijing Normal UniversityInventors: Yiming Yan, Yejun He, Xunliang Ding, Dachun Wang, Andong Liu, Baozhen Chen, Fuzhong Wei
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Patent number: 4973688Abstract: There is disclosed a method for the production of 1-n-dodecylazacycloheptan-2-one by reacting caprolactam with 1-bromododecane in the presence of a phase transfer catalyst under anhydrous conditions using a nonpoisonous hydrocarbon as solvent. The method is a one-pot synthesis employing solid-liquid phase transfer catalysis.Type: GrantFiled: December 15, 1989Date of Patent: November 27, 1990Assignee: Beijing Normal UniversityInventors: Lingchong Yu, Enjian Hou, Jin Li, Xixian Deng