Patents Assigned to Beijing Solobio Genetechnology Company Ltd.
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Patent number: 9969984Abstract: Herein is provided a recombinant lentiviral vector preparation, in which the preparation comprises: a) an effective dose of the recombinant lentiviral vector; b) a histidine hydrochloride buffer for keeping a pH value of the preparation in the range of 6.0-8.0; and c) a carbohydrate.Type: GrantFiled: March 22, 2013Date of Patent: May 15, 2018Assignee: BEIJING SOLOBIO GENETECHNOLOGY COMPANY LTD.Inventors: Jundie Fan, Lixin Jiang, Zhiwen Zhou
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Patent number: 8779113Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: GrantFiled: January 10, 2011Date of Patent: July 15, 2014Assignee: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Patent number: 8383804Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: GrantFiled: January 10, 2011Date of Patent: February 26, 2013Assignee: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Patent number: 8283462Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: GrantFiled: January 10, 2011Date of Patent: October 9, 2012Assignee: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Patent number: 8263761Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: GrantFiled: January 10, 2011Date of Patent: September 11, 2012Assignee: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Publication number: 20110217361Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: ApplicationFiled: January 10, 2011Publication date: September 8, 2011Applicant: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Publication number: 20110217362Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: ApplicationFiled: January 10, 2011Publication date: September 8, 2011Applicant: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Publication number: 20110189264Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: ApplicationFiled: January 10, 2011Publication date: August 4, 2011Applicant: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Publication number: 20110117188Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: ApplicationFiled: January 10, 2011Publication date: May 19, 2011Applicant: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
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Patent number: 7906641Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.Type: GrantFiled: December 16, 2003Date of Patent: March 15, 2011Assignee: Beijing Solobio Genetechnology Company Ltd.Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li