Patents Assigned to Beijing Solobio Genetechnology Company Ltd.
  • Patent number: 9969984
    Abstract: Herein is provided a recombinant lentiviral vector preparation, in which the preparation comprises: a) an effective dose of the recombinant lentiviral vector; b) a histidine hydrochloride buffer for keeping a pH value of the preparation in the range of 6.0-8.0; and c) a carbohydrate.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: May 15, 2018
    Assignee: BEIJING SOLOBIO GENETECHNOLOGY COMPANY LTD.
    Inventors: Jundie Fan, Lixin Jiang, Zhiwen Zhou
  • Patent number: 8779113
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: July 15, 2014
    Assignee: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Patent number: 8383804
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: February 26, 2013
    Assignee: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Patent number: 8283462
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: October 9, 2012
    Assignee: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Patent number: 8263761
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: September 11, 2012
    Assignee: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Publication number: 20110217361
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Application
    Filed: January 10, 2011
    Publication date: September 8, 2011
    Applicant: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Publication number: 20110217362
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Application
    Filed: January 10, 2011
    Publication date: September 8, 2011
    Applicant: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Publication number: 20110189264
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Application
    Filed: January 10, 2011
    Publication date: August 4, 2011
    Applicant: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Publication number: 20110117188
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 19, 2011
    Applicant: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen ZHOU, Yuxia Feng, Conglin Zuo, Yuejuan Li
  • Patent number: 7906641
    Abstract: The invention provides a group of nucleic acid fragments, shown in the sequence listing, for prevention of HIV infection or AIDS and the usage thereof. In the invention, a series of RNA fragments, which are highly homogenous to all the published HIV gene sequences, were obtained by homology compare. The double-stranded RNA (dsRNA) derived from these fragments can effectively inhibit the expression of the HIV genes. The RNA transcribed by plasmid, also can suppress the expression of the HIV in the cell. After the adenovirus or associated virus which carry DNA corresponding above RNA infect the cell, the transcription dsRNA can inhibit the expression of the HIV genes.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: March 15, 2011
    Assignee: Beijing Solobio Genetechnology Company Ltd.
    Inventors: Zhiwen Zhou, Yuxia Feng, Conglin Zuo, Yuejuan Li