Patents Assigned to BEIJING UNIVERSITY OF AGRICULTURE
  • Patent number: 10624336
    Abstract: The present invention belongs to the technical field of embryo cryopreservation. In particular, the present invention relates to an in-vitro embryonic culture medium for improving the thawed recovery rate of an embryo, comprising an inhibitor of Cathepsin L inhibitor, for example, E-64d. The present invention also relates to a method for improving the freezing resistance and the thawing recovery rate of an embryo and a method for freezing an embryo. With the present invention, the freezing resistance and the thawing recovery rate of an embryo are significantly improved.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: April 21, 2020
    Assignee: BEIJING UNIVERSITY OF AGRICULTURE
    Inventors: Yong Guo, Hemin Ni, Yu Chen, Di Liu, Xiangguo Wang, Xiaolong Qi
  • Patent number: 10617734
    Abstract: The present invention relates to a chemical and pharmaceutical technology, and in particular to a STAT3 and ERK signal pathway inhibitor and a use thereof. The present invention provides a STAT3 and ERK signal pathway inhibitor. The inhibitor mainly consists of a mogroside and/or an analog thereof. The mogroside and the analog thereof inhibit the phosphorylation of a transcription factor STAT3 and the phosphorylation of an ERK. The method for preparing the mogroside and the analog has the characteristics of simpleness, strong operability and high purity of products. The present invention further provides a use of the STAT3 and ERK signal pathway inhibitor in the preparation of drugs for treating tumors, which realizes the purposes of inhibiting the proliferation of cancer cells and promoting the apoptosis of cancer cells and has a very good inhibition effect on cancers.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: April 14, 2020
    Assignee: BEIJING UNIVERSITY OF AGRICULTURE
    Inventors: Can Liu, Lanqing Ma, Dequan Dou, Yuanxia Sun, Long Rong, Xiaomeng Zhao, Juntao Li, Yan Wang, Zhengzi Bi, Xiaozhu Bi, Haiwen Hu