Abstract: A method for detecting the content of active ingredients of a compound Sophorae flavescentis radix injection and the fingerprint spectrum thereof. The method comprises using high performance liquid chromatography to perform detection, wherein the high performance liquid chromatography is operated under the condition of a C18 chromatographic column, and active ingredients comprise matrine, oxymatrine, macrozamin, sophocarpine, oxysophocarpine, sophoridine, or/and piscidic acid. The present method is an improved method for performing detection on a compound Sophorae flavescentis radix injection, by means of same, seven ingredients in the compound Sophorae flavescentis radix injection can be simultaneously determined, and a chromatographic fingerprint spectrum can be constructed, thereby providing a technical method for quality control of a compound Sophorae flavescentis radix injection.
Type:
Application
Filed:
November 30, 2021
Publication date:
February 8, 2024
Applicant:
BEIJING ZHENDONG GUANGMING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD.
Abstract: A method for detecting the monosaccharide and oligosaccharide content and fingerprint spectrum of a compound Sophora flavescens injection, comprising: carrying out detection by using a high-performance liquid chromatography-evaporation light scattering detection method, wherein the monosaccharides and oligosaccharides are D-anhydrous glucose, D-fructose, sucrose and pinitol. The present method is an improved method for detecting monosaccharides and oligosaccharides of a compound Sophora flavescens injection, and can measure four saccharide components in the compound Sophora flavescens injection at the same time, and constructs an HPLC-ELSD fingerprint spectrum to provide a technical method for the quality control of the saccharide components in the compound Sophora flavescens injection.
Type:
Application
Filed:
November 30, 2021
Publication date:
January 18, 2024
Applicant:
BEIJING ZHENDONG GUANGMING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD.
Abstract: The invention relates to the field of traditional Chinese medicine, in particular to provides traditional Chinese medicine compositions for the treatment of psoriasis, their preparations and their preparation methods. The Chinese medicine compositions of the invention are consisted of 20-80 parts of Rumex madaio, 20-80 parts of Radix sophora flavescens, 10-50 parts of Herba Siphonostegiae, 10-40 parts of Chinese pulsatilla chinensis, and 5-30 parts of Acacia catechu, by weight. The invention also includes the preparation methods of the traditional Chinese medicine compositions and the preparations containing the traditional Chinese medicine compositions and method for preparing the same.
Type:
Grant
Filed:
September 27, 2016
Date of Patent:
April 6, 2021
Assignee:
Beijing Zhendong Guangming Pharmaceutical Research Institute Co., Ltd.