Abstract: In some examples, a conduit system includes a conduit defining a conduit lumen configured to provide a flow path for a fluid between a container and a medical machine. A flexible member secured to the conduit is configured to substantially occlude (e.g., close) the conduit lumen when deformed by a force acting on the flexible member toward the lumen. The conduit system includes a clamp head configured to pass through an opening defined by the conduit and exert the force on the flexible member, such that the flexible member occludes the conduit lumen. In examples, the conduit is substantially rigid conduit configured to provide a relatively constant geometry and/or flow path for the discharge of a nozzle.

Abstract: A connector including a plug configured to mechanically mate with a socket to establish a connection from a first conduit to a second conduit. The plug is configured to mechanically engage the first conduit and the socket is configured to mechanically engage the second conduit. In examples, the plug is configured to insert into a socket well of the socket. The connector includes an electromagnet configured to energize and produce a magnetic field when the plug mechanically mates with the socket. The electromagnet is configured such that the magnetic field generates an electromagnetic force on a plug armature of the plug to help sustain the mechanically mating of the plug and the socket. The connector may include a user device configured to provide an output indicating when the plug is mechanically mated or unmated with the socket.

Abstract: In some examples, a connector includes a plug configured to mechanically couple with a socket to establish fluid communication from a first conduit to a second conduit. The plug is configured to mechanically engage the first conduit and the socket is configured to mechanically engage the second conduit. In examples, the plug is configured to insert into a socket well of the socket. The connector includes a clamp head configured to mechanically engage the plug when the plug mechanically couples with the socket. The clamp head is configured to mechanically engage the plug to help sustain the mechanical coupling of the plug and the socket. In some examples, the connector may include an output device configured to provide an output indicating when the plug is mechanically coupled with the socket.

Abstract: A peritoneal dialysis cassette that uses an external pump to drive fluid through the peritoneal dialysis cassette is provided. The peritoneal dialysis cassette can include two inlet/outlet ports connected to an inlet and outlet of the external pump. The external pump drives fluid through fluid passages in the peritoneal dialysis cassette connecting a plurality of other inlet/outlet ports, with one or more valves usable to selectively direct fluid through the peritoneal dialysis cassette.

Abstract: A filter for purifying blood (1, 100), comprising a container body (2, 102) in which there are: —an intake port (3, 103) for an incoming blood stream (4, 104), —a first discharge port (5, 105) for an outgoing blood stream (6, 106), and —a second discharge port (7, 107) for a purified plasma stream (8, 108); the container body (2, 102) comprises first filtering means (9, 109) adapted to separate a stream of plasma to be purified (10, 100) from the incoming blood stream (4, 104), and second filtering means (11, 111) adapted to purify the stream of plasma to be purified (10, 110) to obtain the purified plasma stream (8, 108).

Abstract: The present invention provides a secondary packaging container and a method for packaging hemodialysis dialyzers. The container may comprise a box and at least a packaging division positioned horizontally to fit in the box. The packaging division contains a plurality of housing cavities capable of receiving a plurality of dialyzers. The disclosed secondary packaging container and method protects the integrity of hemodialysis dialyzers during transportation and storage.

Abstract: Circulating free lambda and kappa free light chains in blood play a role in the pathogenesis of acute renal failure due to myeloma. Coupled plasma filtration and adsorption allows separation of plasma from blood and treatment of the plasma through a cartridge containing a sorbent or resin material, such as hydrophobic divinylbenzene styrenic resins having an average bead diameter of 75 microns, an average pore diameter of 30 nm, and a surface area of 700 m2/g. Lambda and kappa free light chain concentrations progressively decrease during coupled plasma filtration and adsorption treatment resulting in significant reductions by the end of the treatment.

Abstract: It is described a kit for treating a systemic inflammatory related disease comprising a) a high permeability filter having a pore size designed to let inflammatory mediators to pass and b) means to retain said mediators but not serum albumin.

Abstract: A method of assisting in regenerating a patient's liver includes fluidly coupling a first end of a conduit with a first blood vessel of the patient that carries oxygenated blood. A second end of the conduit is fluidly coupled with a second blood vessel of the patient that carries blood to the patient's liver. Oxygenated blood is allowed to flow from the first blood vessel, through the conduit and to the liver via the second blood vessel of the patient.

Abstract: Device (10) and machine (1000) for regeneration of a human liver (L). The device (10) comprises at least two catheters (11, 12) and a three-way connection (13) between the two catheters (11, 12).

Abstract: It is described a kit for treating a systemic inflammatatory related disease comprising a) a high permeability filter having a pore size designed to let inflammatory mediators to pass and b) means to retain said mediators but not serum albumin.