Abstract: The present invention provides a method of treating, delaying the onset, delaying progression of, reducing the incidence of or reducing the severity of amyotrophic lateral sclerosis in a subject, the method comprising administering to a subject an agent, which interferes with IgG-A2BG2 expression, IgG-A2BG2 function or IgG-A2BG2 interaction with CD16 in said subject.

Abstract: This invention provides a fully automatic method and a system for detecting and classifying cardiac arrhythmias from a surface ECG record. The method defines four relevant parameters whose values are extracted from said ECG record. Clinically relevant conclusions are assigned to various combinations of the obtained values of said parameters. The method can be employed for detecting fetal QRS complexes from abdomen ECG of a pregnant woman.

Abstract: The invention is a surface plasmon resonance (SPR) sensor to determine the presence and quantity of biological or chemical entities in an analyte. The sensor comprises a metal periodic structure deposited as a thin layer of a noble metal, comprising a one dimensional array of nanoslits or a two dimensional array of nanoholes on a transparent dielectric substrate, a nm-thick layer of transparent dielectric protection layer on top of the metal periodic structure and a functionalization layer, which acts as a binding layer to biological or biochemical entities in an analyte that is in contact with the functionaliztion layer.

Abstract: Provided are a method and an apparatus for modifying particle size of powders in closed items, comprising the exposure of said items to external electric field of suitable parameters. The degree of agglomeration of the particles can be increased or decreased. Applications to neutralization of harmful powders in mails, to dry agglomeration and to volatilization of powders in food industry and in pharmacology are described.

Abstract: Provided is a method for the electrochemical conversion of carbon dioxide to fuels. The method employs reducing CO2 in an electrochemical cell using an aerogel carbon electrode and an ionic liquid membrane, thereby providing a carbon-based combustible.

Abstract: The invention is an apparatus and method for free space pumping of active double-clad fiber based lasers and amplifiers. The apparatus comprises a laser emitting a signal laser beam; an active double-clad fiber having a core defining an optical axis of the apparatus and a pump cladding defining a cone of numerical aperture; an optical arrangement directing the signal laser beam along the optical axis through the core of the active double-clad fiber; at least one pump source emitting a pump beam; at least one delivery means coupling the pump beam to the pump cladding of the active double-clad fiber; and an optical arrangement coupling the amplified signal laser beam exiting the active double-clad fiber out of the apparatus.

Abstract: There is provided a composite membrane, which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. There is also provided a composite membrane for water application(s), which may include an electronically conductive porous support and an electro-polymerized selective layer. Moreover, there is provided a composite membrane for gas application(s), which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. There is also provided a membrane system which may include at least one composite membrane which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. In addition there is provided a method for the preparation of a composite membrane.

Abstract: A polymer electrolyte membrane (PEM) for fuel cells is provided, as well as a method for manufacturing the PEM by direct casting on the fuel cells electrodes. The PEM, consisting of an ionic liquid entrapped within polysiloxane-RTV matrix, is stable at high temperatures, in acidic and basic environments, and exhibits a high conductivity, without the crossover of methanol.

Abstract: The invention is a method of phase separation in liquid mixtures comprising two or more components. The method comprises the steps of inserting the liquid mixture between suitably shaped and positioned electrodes and applying a voltage to the electrodes in order to produce a non-uniform electric field between the electrodes. The phase separation takes place with essentially all electrode geometries and the phase separation is reversible. The method is characterized in that the liquid mixture must contain dissociated positive or negative ions. In this case the phase separation takes place when the applied voltage is a few volts or less and when the temperature is many degrees above the binodal (coexistence) temperature Tc. The invention has many practical applications including: electrical field controlled lubrication, influencing the kinetics and spatial dependence of chemical reactions in liquid environments, controlling the propagation of light, and controlling the opacity of a window.

Abstract: Provided are a method and an apparatus for modifying particle size of powders in closed items, comprising the exposure of said items to external electric field of suitable parameters. The degree of agglomeration of the particles can be increased or decreased. Applications to neutralization of harmful powders in mails, to dry agglomeration and to volatilization of powders in food industry and in pharmacology are described.

Abstract: The invention provides a rapid and economical process for manufacturing a transparent, spinel based ceramic. A transparent body of sintered magnesium aluminate spinel having excellent optical and mechanical properties is provided in a single-stage thermal process.

Abstract: A method is provided for exfoliation of carbon nanotubes and for the preparation of a stable aqueous suspension thereof containing dispersed, essentially single tubes, using a water-soluble polymeric material. A powder of carbon nanotubes is further provided, that can be re-dispersed to form a stable suspension. The nanotubes can be used in electronics, printing, coatings, thin layers, molecular machines, and for the production of composite materials.

Abstract: The present invention provides bioconjugates comprising a sulfated polysaccharide such as alginate sulfate and hyaluronan sulfate and at least one bioactive polypeptide capable of binding a sulfate group of said sulfated polysaccharide. The bioactive polypeptide can be a heparin-binding polypeptide and/or a positively-charged polypeptide. Also, provided are delivery systems and methods for sustained release of said bioactive polypeptide(s) using said bioconjugates.

Abstract: The invention is directed to tissue-engineered biografts, methods for preparing the biografts of the invention, and methods for repairing a damaged myocardium in a mammal. The methods of the invention can include providing a three-dimensional porous polysaccharide matrix; introducing mammalian cells into said matrix; growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed; and transplanting the tissue-engineered biograft onto myocardial tissue or myocardial scar tissue of said mammal. The tissue-engineered biograft of the invention can form a contracting tissue. The methods of the invention can optionally include removing scar tissue or dead tissue from the site of implantation prior to transplanting the biograft.

Abstract: The invention provides a composition of matter comprising molecular iodine and tetraglycol.

Abstract: Modular apparatus for regulating the harmonics of current drawn from power lines by electric equipment, comprising a first rectifier circuit module, consisting of an array of rectifying diodes; a second Switch and Controller Assembly (SCA) module, which comprises a power switch and controller and their interconnections; an input inductor for filtering the current drawn from the rectifier module; and an output capacitor, for filtering the output voltage ripple at the load. The inlet of the rectifier is connected to the power line and an outlet of the rectifier module is connected to the SCA. The inlet of said SCA is connected to the rectifier, via an inductor and the outlet of said SCA is connected to the output capacitor. The inlet of the inductor is connected to the rectifier, the outlet of the inductor is connected to the inlet of said SCA, and the capacitor is connected in parallel with the load.

Abstract: A device for generating hand function, having an S-type splint consisting a forearm portion extending along the palmar side of the forearm, a palmo-dorsal transition portion leading to a dorsal portion extending across the dorsal side of the carpal bones of the hand, and a palmar portion, at least the end of which touches the palm of the hand of the wearer of the device at least indirectly, and a plurality of electrodes, at least indirectly mounted on the splint in positions in which they can make contact with skin portions directly overlying muscles to be stimulated. The electrodes are connectable to an electronic circuit adapted to produce, upon activation, stimulation currents delivered via combinations of the electrodes in predetermined, timed sequences to preselected groups of muscles. At least one switch is actuatable by the wearer of the device, by which switch the predetermined, timed sequences can be initiated.

Abstract: The invention provides an insecticidal composition comprising Diazinon ensulated in microcapsules, the microcapsules having an encapsulating wall formed essentially from the reaction product of toluene diisocyanate and a polyfunctional amine, and further provides a process for encapsulating Diazinon in a microcapsular formulation comprising providing an aqueous phase containing a non-basic emulsifier, providing an organic phase containing toluene diisocyanate and Diazinon, combining the aqueous and organic phase to form an oil in water emulsion, and adding an aqueous solution of a polyfunctional amine with agitation to the emulsion, whereby the amine reacts with the toluene diisocyanate to form microcapsular envelopes about the Diazinon material.

Abstract: A system for gamma-ray interference-free fast-neutron radiography is provd. The system comprises a radiation detector adapted to distinguish between neutron and gamma radiation, an imaging device transducing object-point related signals generated by the object-modified neutron and gamma radiation in the radiation detector. The system also includes a pulse-shaped discrimination and gating device for passing only neutron-induced image-producing pulses so as to filter out the gamma-ray induced, interfering signals.

Abstract: A method and apparatus are described for generating power utilizing press-retarded osmosis, in which a concentrated solution at a high hydraulic pressure is passed along one face of a semi-permeable membrane, and a dilute solution at a low hydraulic pressure is passed along the opposite face of the membrane to effect, by pressure-retarded-osmosis, the passage of at least a part of the dilute solution through the membrane forming a pressurized mixed solution. The potential energy stored in the pressurized mixed solution is converted to useful energy by depressurizing and repressurizing only the dilute solution.