Abstract: A mandrel (300) for holding an intraocular lens blank (200) during manufacturing includes an intraocular lens holding section configured to hold an intraocular lens, the intraocular lens holding section including: a central cavity (310) configured to hold a mounting material (315) such that the mounting material contacts an optic of the intraocular lens blank when the intraocular lens blank is mounted on the mandrel, and a projection (325) extending around a periphery of the central cavity, the projection having an outer wall (330) and an inner wall (335), and the projection being configured such that an outer peripheral edge of the intraocular lens blank extends up to or beyond the projection when the intraocular lens blank is mounted on the mandrel. A second mounting material (320) is deposited in the first trench (340) and then the haptic is milled using e.g. an end mill (365).

Abstract: An intraocular lens (IOL) with excellent non-glistening characteristics comprising at least one copolymer comprising: (a) one or more first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, (b) one or more second monomeric subunits different from the first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkoxyalkyl side group, (c) one or more third monomeric subunits different from the first and second monomeric subunits, the third monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkylene oxide side group, wherein the first monomeric subunit is present in a greater amount by weight than the second monomeric subun

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: A mandrel (300) for holding an intraocular lens blank (200) during manufacturing includes an intraocular lens holding section configured to hold an intraocular lens, the intraocular lens holding section including: a central cavity (310) configured to hold a mounting material (315) such that the mounting material contacts an optic of the intraocular lens blank when the intraocular lens blank is mounted on the mandrel, and a projection (325) extending around a periphery of the central cavity, the projection having an outer wall (330) and an inner wall (335), and the projection being configured such that an outer peripheral edge of the intraocular lens blank extends up to or beyond the projection when the intraocular lens blank is mounted on the mandrel. A second mounting material (320) is deposited in the first trench (340) and then the haptic is milled using e.g. an end mill (365).

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: A method comprises providing a lens blank, a precision positioning device, an illumination device, and a vision system, wherein the lens blank includes at least one feature whose position is known relative to a position of an optic center of the lens blank, and wherein the vision system comprises an image sensor and a processor; mounting the lens blank on the precision positioning device; illuminating the lens blank with the illumination device; viewing the lens blank with image sensor of the vision system; determining the position of the at least one feature using the processor; and determining the position of the optic center of the lens blank based on the position of the at least one feature using the processor.

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: A composition comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring. The chromophore is a kynurenine-based compound. Methods of making and using the composition are also provided. The composition can be used in an ophthalmic lens or device for protecting the retina by blocking UV rays and filtering violet rays.

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: A method comprises providing a lens blank, a precision positioning device, an illumination device, and a vision system, wherein the lens blank includes at least one feature whose position is known relative to a position of an optic center of the lens blank, and wherein the vision system comprises an image sensor and a processor; mounting the lens blank on the precision positioning device; illuminating the lens blank with the illumination device; viewing the lens blank with image sensor of the vision system; determining the position of the at least one feature using the processor; and determining the position of the optic center of the lens blank based on the position of the at least one feature using the processor.

Abstract: The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers.

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: A method and apparatus for aligning and positioning a surface such that the optical and/or cylinder axis of the surface is precisely aligned with a fixture for the purpose of assembly or further mechanical operations such as machining and polishing. According to another aspect of the invention, a lens apex is located and precisely positioned a constant distance from a reference point. In order to implement the above, a method and apparatus is disclosed for optically aligning and positioning surfaces using a precision laser displacement measurement device, an X-Y-Z micron stage, and a microprocessor (or computer) capable of performing curvature analysis.

Abstract: The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers.

Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

Abstract: The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers.

Abstract: A contact lens of high water content and extremely high water balance made of a homopolymer or copolymer of 2,3-dihydroxypropyl methacrylate and methods of making such contact lenses, and polymers and hydrogels useful in such contact lenses.

Abstract: A contact lens of high water content and extremely high water balance made of a homopolymer or copolymer of 2,3-dihydroxypropyl methacrylate and methods of making such contact lenses, and polymers and hydrogels useful in such contact lenses.

Abstract: A contact lens and a contact lens blank having increased dimensional stability are constructed from a copolymer of 2,3-dihydroxypropyl methacrylate and 2-hydroxyethyl methacrylate, wherein the copolymer of 2,3-dihydroxypropyl methacrylate and 2-hydroxyethyl methacrylate has either an absolute water balance ratio greater than 8 or a relative water balance ratio greater than 2 relative to a polymer of 2-hydroxyethyl methacrylate.

Abstract: A method of making a one-piece intraocular lens formed from a copolymer of a hydrophilic monomer and an alkoxy-alkylmethacrylate. The intraocular lens is foldable so as to be insertable through a small incision in the eye. Copolymers of the lens have an equilibrium water content of from about 10 to about 38 percent by weight based on the total weight of the hydrated copolymer.