Patents Assigned to BERTIS INC
  • Publication number: 20250102506
    Abstract: The present invention relates to a method of diagnosing cancer using proteins (or fragments thereof), which are specifically expressed in cancer, or genes encoding the proteins. According to the present invention, specific proteins and fragments thereof useful for cancer diagnosis are discovered among blood proteins, and they may be used as diagnostic biomarkers to diagnose in particular breast cancer simply and accurately at an early stage, thereby significantly lowering the mortality rate of patients with related diseases.
    Type: Application
    Filed: March 30, 2023
    Publication date: March 27, 2025
    Applicant: BERTIS INC
    Inventors: Sungsoo KIM, Youngmin PARK, Hyeonseok SHIN, Seungman HAN, Dongyoung NOH
  • Publication number: 20240053309
    Abstract: The present invention relates, with respect to liquid chromatograph-mass spectrometry (LC-MS), to a technique for predicting retention time of samples and thereby accurately separating signals of samples having mass that are close to each other to improve multiplexity of quantitative measurements.
    Type: Application
    Filed: April 28, 2021
    Publication date: February 15, 2024
    Applicant: BERTIS INC
    Inventors: Sejun SONG, Sungsoo KIM, Hyeonseok SHIN
  • Publication number: 20240043937
    Abstract: The present invention relates to a method of determining the subtype of a pancreatic ductal adenocarcinoma patient through proteogenomic analysis of PDAC. The method of determining the subtype of pancreatic cancer according to one embodiment of the present invention comprises steps of: (1) pulverizing a pancreatic ductal adenocarcinoma lesion tissue isolated from a pancreatic ductal adenocarcinoma patient; (2) obtaining a peptide sample for the patient by extracting and digesting proteins from the lesion tissue; (3) measuring the expression levels of representative genes of pancreatic ductal adenocarcinoma subtypes 1 to 6 from the peptide sample for the patient; and (4) determining the subtype of the pancreatic ductal adenocarcinoma patient by comparing the expression levels of the representative genes of pancreatic ductal adenocarcinoma subtypes 1 to 6.
    Type: Application
    Filed: August 26, 2021
    Publication date: February 8, 2024
    Applicant: BERTIS INC
    Inventors: Sangwon LEE, Jingi BAE, Dowoon NAM, Daehee HWANG, Jin-Young JANG, Cheolju LEE, Sungho SHIN, Min-Sik KIM
  • Publication number: 20240011979
    Abstract: The present disclosure relates to a composition for detecting or measuring an analyte and an analysis method using the composition. In particular, efficiency and performance of sample analysis may be greatly improved through the composition and analysis method of the present disclosure.
    Type: Application
    Filed: October 27, 2022
    Publication date: January 11, 2024
    Applicant: BERTIS INC.
    Inventors: Sung Soo KIM, Jaehong LEE
  • Publication number: 20230236158
    Abstract: Disclosed are a mutually independent dual online liquid chromatography device and a control method thereof.
    Type: Application
    Filed: January 20, 2023
    Publication date: July 27, 2023
    Applicants: Korea University Research and Business Foundation, BERTIS INC.
    Inventors: Sang-Won LEE, Chaewon KANG
  • Publication number: 20230113788
    Abstract: The present invention provides a system for predicting the spectral profile of a peptide, wherein the spectrum of a sample to be checked can be efficiently analyzed by machine learning properties of the peptide and generating training data for predicting the spectral profile.
    Type: Application
    Filed: February 26, 2021
    Publication date: April 13, 2023
    Applicant: BERTIS INC
    Inventors: Hyeon Seok SHIN, Sung Soo KIM
  • Publication number: 20230074311
    Abstract: The present invention relates to a composition capable of cancer diagnosis, a diagnostic kit comprising same, and a method for providing information for cancer diagnosis using the composition. When a biomarker of the present invention is used, it is possible to accurately and conveniently diagnose cancer, particularly breast cancer, in an early stage, and furthermore, it is possible to diagnose the stage of cancer and predict therapeutic responsiveness or post-treatment prognosis.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 9, 2023
    Applicant: BERTIS INC
    Inventors: Sung Soo KIM, Seung Man HAN
  • Publication number: 20220268776
    Abstract: The present invention relates to a biomarker for diagnosing pancreatic cancer and use thereof. The marker according to the present application can significantly predict or determine, through a 14-multimarker panel, the onset likelihood, early diagnosis, and severity of pancreatic cancer or precancerous lesions of pancreatic cancer, and can be used in research on the tumorigenesis of pancreatic cancer.
    Type: Application
    Filed: July 9, 2020
    Publication date: August 25, 2022
    Applicant: BERTIS INC
    Inventors: Youngsoo KIM, Yoseop KIM, Minsoo SON, Jin-Young JANG
  • Publication number: 20220127679
    Abstract: The present disclosure relates to a composition capable of cancer diagnosis, a diagnostic kit comprising same, and a method for providing information for cancer diagnosis using the composition. When a biomarker of the present disclosure is used, it is possible to accurately and conveniently diagnose cancer, particularly breast cancer, in an early stage, and furthermore, it is possible to diagnose the stage of cancer and predict therapeutic responsiveness or post-treatment prognosis.
    Type: Application
    Filed: February 13, 2020
    Publication date: April 28, 2022
    Applicant: BERTIS INC
    Inventors: Sung Soo KIM, Seung Man HAN