Abstract: According to one general aspect, there is an double-balloon breast brachytherapy catheter comprising, an outer-balloon that is filled with a liquid substance or air via an out-balloon-filler; an inner-balloon that is filled with a liquid substance or air via an inner-balloon-filler, wherein the inner-balloon is inserted inside the outer-balloon; a plurality of radiation-tubes connected to an outside boarder of the inner balloon; a vacuum-tube that is wrapped around an exterior of the outer-balloon, wherein the vacuum tube is used to remove human fluids and air to create a void; and a flexible-shaft is connected to an upper-head, a proximal-tail and a distal-tip, wherein the upper-head is covered by the outer-balloon, the inner-balloon, the plurality of radiation-tubes and the vacuum-tube.

Abstract: The invention provides devices and methods used to locate target areas within a patient for repeat therapeutic treatments. In the invention, fiduciary markers made of metal or metal alloys are placed within a patient near or at a target site as reference coordinates for particular body locations on the patient. Repeat treatments may then be given to the patient over a period of time based on the coordinates given by the fiduciary markers. The fiduciary markers are specially shaped or put into strand to improve marker attachment and prevent marker migration.

Abstract: A system to provide enhanced computational efficiency in a simulation of particle transport through a medium, program product, and related methods are provided. The system can include a simulation data administrator server having access to an interaction database including records related to parameters describing interactions of particles in an absorbing medium to provide particle interaction parameters, and a simulated dose calculation computer in communication with the simulation data administrator server through a communications network.

Abstract: A system and associated methods to determine an optimal radiation beam arrangement are provided. The system includes a computer planning apparatus which includes a treatment plan optimization computer having a memory and an input device in communication with the treatment plan optimization computer to provide user access to control functions of plan optimization software. An image gathering device is in communication with the treatment plan optimization computer through a communications network to provide an image slice of the tumor target volume and the non-target structure volume. The plan optimization software computationally obtains and then optimizes a proposed radiation beam arrangement iteratively based on constraints to form an optimized radiation beam arrangement. A conformal radiation therapy delivery device in communication with the treatment plan optimization computer through the communications network then applies the optimized radiation beam arrangement to the patient.

Abstract: A system and associated methods to determine an optimal radiation beam arrangement are provided. The system includes a computer planning apparatus which includes a treatment plan optimization computer having a memory and an input device in communication with the treatment plan optimization computer to provide user access to control functions of plan optimization software. An image gathering device is in communication with the treatment plan optimization computer through a communications network to provide an image slice of the tumor target volume and the non-target structure volume. The plan optimization software computationally obtains and then optimizes a proposed radiation beam arrangement iteratively based on constraints to form an optimized radiation beam arrangement. A conformal radiation therapy delivery device in communication with the treatment plan optimization computer through the communications network then applies the optimized radiation beam arrangement to the patient.

Abstract: A system to analyze the geometry of a radiation treatment apparatus, software, and methods are provided. The system includes an apparatus having a rotating assembly and a trackable body or plurality of trackable bodies, to mark a location of a preselected portion of the rotating assembly. The system also includes a trackable reference fixture and can include a constant orientation trackable body. A determiner determines the position and/or orientation of the trackable bodies, the trackable reference fixture, and constant orientation trackable body. The determiner then determines the geometry of the treatment apparatus to analyze a coordinate system used by an operator. The determiner can have a memory and geometry analyzing software stored in the memory to analyze the treatment apparatus geometry.

Abstract: A system, tracker, program product, and methods to facilitate and verify proper target alignment for radiation delivery are provided. The system includes a radiation delivery apparatus having a radiation emitter, a rotating assembly controlled by a controller, and an application computer which provides treatment delivery instructions to the controller. The system also includes a trackable body having a trackable body reference point to be positioned adjacent a surface point of a patient to determine a position of such surface point. The system also includes an apparatus to track a trackable body which has a trackable body detector to detect a position of indicators carried by the trackable body and a trackable body determiner to determine a position of the trackable body reference point.

Abstract: A system to monitor a geometry of a treatment apparatus, an apparatus, a trackable assembly, program product, and methods are provided. The system includes a treatment apparatus having a radiation emitter, a rotating assembly controlled by a controller, and an application computer, which provides treatment delivery instructions to the controller. The system can also include a trackable assembly connected to the rotating assembly and having a fixedly connected first trackable body which functions as a reference fixture and a pivotally connected second trackable body which provides data used to determine a rotation angle of the rotating assembly. The system also includes an apparatus to track a trackable body which has a trackable body detector to detect a position of the indicators carried by the first and the second trackable bodies and a determiner to determine and verify the location of the origin of an isocenter coordinate system and to determine rotational path data about the rotating assembly.

Abstract: Radioactive sources are manufactured for treating a tumor or cancerous area occurring around a conduit or duct in the body by emitting X-rays to destroy or reduce the tumors. The sources contain ytterbium which is substantially enriched in 168Ytterbium and which is activated by exposure to neutron flux so as to contain a minor, but significant, fraction of X-ray and gamma-emitting 169Ytterbium. The radioactive 169Ytterbium source is inserted through a catheter or applicator or needle to the site of the cancer where it is maintained in position for a period of time to reduce the occurrence of cancer. The ytterbium also acts as an X-ray-opaque marker to facilitate external visualization of the sources during their delivery to the treatment site. The sources are encased in a shell to prevent direct contact of the radioactive material with human tissue. This encapsulation may be formed by welding a pair of end caps to a tubular member.

Abstract: A system to provide enhanced computational efficiency in determining dose in a media of varying density from a high-energy radiation-beam for radiation treatment, program product, and related methods are provided. The system can include a radiation treatment planning computer and radiation treatment planning program product adapted to enhance optimization of a radiation treatment plan for delivering radiation to a complex medium defining a patient volume.