Abstract: Novel Enhanced Abulaotry Medical Devices for example a PATCH PUMP systems use form factor improvements and includes GUIs to procure weight as a priming data point and function as all BETA BIONICS ambulatory medical devices driven by software and algorithm sets, likewise bihormonal and third party interfacing approaches are taught.

Abstract: A method for administering medicament from a medical device includes receiving, from a sensor, a first biomarker level in a user, determining a basal rate of endogenous glucose production based on one or more biomarker levels, determining, based on the basal rate, an amount of medicament to transfer to the user, transmitting a first instruction to the medical device to deliver the amount of medicament to the user, further receiving, from the sensor, a second biomarker level in the user, adjusting the basal rate based on the first biomarker level and the second biomarker level, adjusting the amount of medicament to transfer to the user based on the adjusted basal rate, and transmitting a second instruction to the medical device to deliver the amount of medicament to the user.

Abstract: An ambulatory medical device can detect a device condition and determine if the device condition satisfies a set of normal operating parameters. If the normal operating parameters are not satisfied, the ambulatory medical device can determine if the device condition stratifies a set of minimum operating parameters. If the minimum operating parameters are satisfied, the ambulatory medical device can maintain a delivery of therapy to a subject and generate an alert based on the device condition.

Abstract: A method for administering medicament from a medical device includes receiving, from a sensor, one or more amounts of biomarkers in blood of a user, determining a response to one or more medicaments responsive to the one or more amounts of biomarkers, adjusting a gain-term based on the response to the one or more medicaments, the gain-term configured to control an amount of medicament that is administered from an ambulatory medical device, and transmitting an instruction to the ambulatory medical device to deliver the amount of medicament to the user.

Abstract: Embodiments of an enhanced PATCH PUMP system leverage cognitive load free set up and enable users to have form factors and priming based on body weight with no other set up or data needed to use systems which likewise host further combination of patch pumps and algorithmic base schematics.

Abstract: Patch pump configurations and combinations with modular aspects of dosing, storage and delivery processing of medicaments optimizes pairing and updating of the correct algorithms with minimized cognitive burdens—likewise offered for consideration methods for administering medicament from a medical device including snap together, prime with body weight and be connected—with no further steps.

Abstract: The new and future systems for low cognitive load disposable and durable medicament pumping systems now include at least one of pump embodiments for pairing of an APP in half-of a dozen embodiments respecting all known and to be installed features of the Beta Bionics (Irvine, CA patent estate and inchoate matters).

Abstract: The iLet BIONIC PANCREAS system improves alarm annunciation and prioritization with the enumeration of conditional improvements for pairing of, for example, the iLet APP & iLet BIONIC PANCREAS (along with patch pumps in half-of a dozen embodiments) respecting silence conditions for alarms; learning glucagon response; real time mirrored display, data sharing; pairing processes; confidence reminders; widgets; and iLet APP control features for bolusing meal announcements; user providing input and changes mind; and ILet APP therapy Restore.

Abstract: Novel enhanced methods for adapting meal boluses using post-prandial glucose values enable systems that titrate meal doses based on post-prandial glucose excursions where the pattern of the glucose excursion may be evaluated in the post-prandial period to include the minimum and/or maximum excursion, the area under the curve (glucose relative to target glucose) or difference between the glucose and an expected glucose response based on estimated carbs consumed and the glucose response of the insulin delivered. Additionally, in a bihormonal implementation, the meal dose may be further adapted based on the amount of glucagon delivered for example reducing the meal size if glucagon is delivered. Apps are disclosed, taking, for example, blousing meal announcements differently to drive control parameters than previously disclosed among prior art systems, including without adaptation of glucose targets comprised of Algo Two Point Zero et seq.

Abstract: Automated glucose level control system that provide therapy to a subject, such as glucose control, are disclosed. The system generates dose control signals using control algorithms configured to autonomously determine doses of insulin to be infused into a subject. When the system determines that an initial dose control signal does not indicate health-appropriate therapy, the system can modify a manual therapy instruction and transmit an emergency dose control signal to the medicament pump. Disclosed systems and devices can track insulin therapy administered to the subject over a tracking period, including storing an indication of the autonomously determined doses of insulin delivered to the subject. The system can generate a backup therapy protocol with insulin therapy instructions based at least in part on the insulin therapy administered to the subject over the tracking period.

Abstract: A pump device for pushing a metered quantity of a stored volume of a fluid medicament into a patient includes a drive motor including a rotational output rotating about a motor axis when energized. A piston is receivable within a reservoir including a reservoir axis and having an interior space in which the volume of the medicament is receivable and an outlet through which the metered quantity is expellable. The piston is movable within the reservoir along the reservoir axis so as to displace the metered quantity when moved in a direction of the outlet, The reservoir is located laterally adjacent to the drive motor, the reservoir axis and the motor axis running codirectionally. A leadscrew which is rendered non-rotatable and is affixed to the piston.

Abstract: A smart charging station may be capable of accessing data from an ambulatory medicament device at particular times, such as when the ambulatory medicament device is charging or connected to the charging station. The smart charging station may then communicate the data to another electronic system, such as a remote system. Advantageously, the charging station enables an ambulatory medicament device that may not be capable of communicating with a remote system to transfer ambulatory medicament device data to the remote system. Further, the remote system may communicate with the ambulatory medicament device via the charging station enabling, for example, control parameter updates, software updates, or permission modifications, among other communications with the ambulatory medicament device regardless of whether direct communication with the ambulatory medicament device is possible.

Abstract: Systems and methods relate to an ambulatory medicament device that can generate a dose control signal to cause a medicament pump to infuse medicament into a subject. The system can analyze status to determine whether an alarm condition for the ambulatory medicament device or for a subject is already present in a list of pending alarm conditions. If the alarm is not present, the system can determine a severity level of the alarm condition from among a plurality of severity levels and annunciate the alarm condition using one or more annunciation patterns selected based on the severity level of the alarm condition for the medicament device or for the subject. The system may maintain an indication of the alarm condition on the list of pending alarm conditions until the alarm condition is resolved.

Abstract: Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament cartridges, cartridge connectors, a multi-channel fluid conduit, and an infusion set. The infusion pump can have an inductively chargeable battery assembly that can be charged by an inductive charging pad.

Abstract: An ambulatory medicament device can generate a dose control signal for delivery of medicament to a subject and secure at least some functionality of a user interface of the ambulatory medicament device. The ambulatory medicament device can have a locked state that restricts modification of at least one control parameter. The ambulatory medicament device can have an unlocked state that allows modification of at least one control parameter. The ambulatory medicament device can accept a user input of a security code that is validated against a passcode to enter from the locked state to the unlocked state.

Abstract: An ambulatory medical device can detect a device condition and determine if the device condition satisfies a set of normal operating parameters. If the normal operating parameters are not satisfied, the ambulatory medical device can determine if the device condition stratifies a set of minimum operating parameters. If the minimum operating parameters are satisfied, the ambulatory medical device can maintain a delivery of therapy to a subject and generate an alert based on the device condition.