Patents Assigned to Beta-Cell, N.V.

Method for producing preparations of mature and immature pancreatic endocrine cells, the cell preparation and its use for treatment of diabetes mellitus

Patent number: 6686197

Abstract: A method for preparing a preparation of mammalian pancreatic endocrine cells comprising the steps: dissociating intact pancreatic tissue into a cell suspension comprising single cells and cell aggregates; enriching said cell suspension with regard to the content in endocrine cells by separating single cells and cellular aggregates with size <100 &mgr;m; and removing contaminating non-endocrine cells by density centrifugation.

Type: Grant

Filed: April 12, 2001

Date of Patent: February 3, 2004

Assignee: Beta-Cell, N.V.

Inventor: Daniel Pipeleers
Method for producing preparations of mature and immature pancreatic endocrine cells, the cell preparation and its use for treatment of diabetes mellitus

Publication number: 20020177228

Abstract: A method for preparing a preparation of mammalian pancreatic endocrine cells comprising the steps: dissociating intact pancreatic tissue into a cell suspension comprising single cells and cell aggregates; enriching said cell suspension with regard to the content in endocrine cells by separating single cells and cellular aggregates with size <100 &mgr;m; and removing contaminating non-endocrine cells by density centrifugation.

Type: Application

Filed: April 12, 2001

Publication date: November 28, 2002

Applicant: Beta-Cell N.V.

Inventor: Daniel Pipeleers

Method for producing preparations of mature and immature pancreatic endocrine cells, the cell preparation and its use for treatment of diabetes mellitus

Method for producing preparations of mature and immature pancreatic endocrine cells, the cell preparation and its use for treatment of diabetes mellitus