Patents Assigned to Beta S.A.
  • Process for obtaining aspart insulin using a yeast strain
    Patent number: 8691530
    Abstract: The present invention refers to a method for producing a human insulin analogue with high efficiency and excellent yield, by means of a biotechnological process comprising transformation of a Pichia pastoris yeast strain. In particular, the invention refers to a biotechnological process for obtaining aspart insulin.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: April 8, 2014
    Assignee: Laboratorios Beta S.A.
    Inventors: Nestor Annibali, Mercedes Goin, Graciela Trejo, Federico Carrizo, Diego Baruque, Analía Morales
  • PROCESS FOR OBTAINING ASPART INSULIN USING A PICHIA PASTORIS YEAST STRAIN
    Publication number: 20110117600
    Abstract: The present invention refers to a method for producing a human insulin analogue with high efficiency and excellent yield, by means of a biotechnological process comprising transformation of a Pichia pastoris yeast strain. In particular, the invention refers to a biotechnological process for obtaining aspart insulin.
    Type: Application
    Filed: July 15, 2010
    Publication date: May 19, 2011
    Applicant: LABORATORIOS BETA S.A.
    Inventors: Nestor Annibali, Mercedes Goin, Graciela Trejo, Federico Carrizo, Diego Baruque, Analía Morales
  • Expression of a human insulin precursor in
    Patent number: 7091032
    Abstract: Methylotrophic recombinant yeast strain producing human insulin precursor, the strain comprising, in its genome, a copy of a first DNA construction and a second DNA construction, wherein the constructions are capably of directing the expression and secretion of human insulin precursor of the formula B(1-30)-Y1-Y2-A(1-21), wherein Y1 is lysine or arginine; Y2 is lysine or arginine; B(1-30) is the B peptide of the human insulin; and B(1-21) is the A peptide of human insulin, and wherein the strain is yeast Pichia Pastoris. DNA constructions and method for obtaining the strain are also provided.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: August 15, 2006
    Assignee: Laboratorios Beta S.A.
    Inventor: Nestor Annibali
  • Method and composition for treating increased androgenic activity
    Patent number: 5506222
    Abstract: The present invention relates to spironolactone contain compositions for application to an area of human skin afflicted with acne, seborrheic condition or hirsutism. N,N-dialkyl lauramides are used as permeation enhancers.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: April 9, 1996
    Assignee: Laboratorios Beta S.A.
    Inventors: Francisco J. E. Stefano, Dario N. R. Carrara
  • Apparatus for folding and stacking of pieces of laundry
    Patent number: 4238060
    Abstract: The disclosure concerns apparatus for stacking folded laundry. A pair of clamping jaws is supported for swinging about a swinging axis. A first pneumatic cylinder is connected through a first rack with a first pinion connected with the first clamping jaw. A second pneumatic cylinder is connected through a second rack with a second pinion connected with the other clamping jaw. The first pneumatic cylinder is stronger than the second pneumatic cylinder, whereby when both pneumatic cylinders are operated, the first pneumatic cylinder swings the clamping jaws together around the swinging axis to deliver laundry to a stacking table and the second pneumatic cylinder acts in opposition to the first pneumatic cylinder to cause the clamping jaws to clamp together.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: December 9, 1980
    Assignee: Beta S.A.
    Inventor: Henry J. Weir