Patents Assigned to BetaGlue Technologies S.p.A
  • Publication number: 20230414861
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: August 14, 2023
    Publication date: December 28, 2023
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Patent number: 11724023
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: August 15, 2023
    Assignee: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20230087252
    Abstract: An anti-tumoral compound for the localized treatment of neoplastic pathologies of malignant kind that cannot be surgically removed or with a high risk of local recurrence, includes: a bicomponent injectable biologic glue; an antineoplastic substance; and an epinephrine-based solution. The compound may be used as an independent therapeutic treatment, as it allows to treat tumoral masses that are not surgically removable, or as a therapeutic treatment complementary to surgical removal or to known ablative techniques (laser, radiofrequency, microwaves, etc.) for a maximization of the efficiency of therapies reducing the risk of neoplastic relapses in the original surgical site. A process for the production of the antitumor compound is also described.
    Type: Application
    Filed: February 9, 2022
    Publication date: March 23, 2023
    Applicant: BetaGlue Technologies, S.p.A.
    Inventor: Giulia Di Capua
  • Publication number: 20230079546
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: August 31, 2022
    Publication date: March 16, 2023
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Patent number: 11464897
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: October 11, 2022
    Assignee: BETAGLUE TECHNOLOGIES S.P.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20220096734
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: October 11, 2021
    Publication date: March 31, 2022
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Patent number: 11141526
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: October 12, 2021
    Assignee: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli