Patents Assigned to Beth Israel Hospital Assoc.
  • Patent number: 5653759
    Abstract: The present invention is an in-vivo methodology for repairing a ruptured or fragmented segment of a pre-existing therapeutic appliance which has been previously surgically positioned or implanted within the body of a living human. The repair methodology provides for specific apparatus and techniques using a guiding catheter and deformable, thermoelastic shape-memory alloy rods in order to access and repair the flawed or failing therapeutic appliance in place. The repair methodology thus eliminates the need for surgical excision procedures and avoids the requirement for replacement substitute units in order to alleviate and solve the problem of having a flawed therapeutic appliance in-vivo.
    Type: Grant
    Filed: July 18, 1995
    Date of Patent: August 5, 1997
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventors: John D. Hogan, Ducksoo Kim
  • Patent number: 5441957
    Abstract: The present invention provides a chemical class of active compounds to be used as efficacious drugs in the treatment of sickle cell disease. The active compounds include imidazole derivatives, nitroimidazole derivatives, and triazole derivatives. These compounds are to be administered by any preferred route of administration including oral, intramuscular, intravenous, and any other parenteral route. If desired, these drugs may also be administered transmucosally, or subcutaneously, or using a dermal patch on the skin. In addition, the methodology is effective for both long term and short term therapy; may be employed prophylactically and/or therapeutically; and may be used in emergency, acute crisis clinical situations.
    Type: Grant
    Filed: November 18, 1993
    Date of Patent: August 15, 1995
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventors: Carlo Brugnara, Seth L. Alper
  • Patent number: 5369014
    Abstract: The present invention is an in-vitro blood assay method for determining the past and/or present use of exogenous erythropoietin by a living subject. The blood assay method detects, identifies, and determines the consequences of using an exogenous erythropoietin to generate an increase in red blood cell production in the living subject and provides a methodology by which to detect and determine both surreptitious as well as authorized therapeutic uses and applications of erythropoietin.
    Type: Grant
    Filed: August 17, 1992
    Date of Patent: November 29, 1994
    Assignee: Beth Israel Hospital Assoc.
    Inventors: Carlo Brugnara, Margot S. Kruskall, Mark A. Goldberg, Linda A. Chambers
  • Patent number: 5300049
    Abstract: The present invention provides a closed, fluid-modulating receiving system for the conveyance, modulation, and collection of fluid matter from its source. The receiving system may be employed under both in vivo and inanimate use conditions for the collection and disposal of fluids which may be infectious, hazardous, or toxic in and of themselves.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: April 5, 1994
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventor: John D. Hogan
  • Patent number: 5295945
    Abstract: The present invention provides a garment to be worn externally on the female person and a method for positioning and securing a radiotherapeutic appliance internally within the female genital organs during local radiation therapy. The garment provides at least one supporting band of material to be worn around the female body and provides access on-demand to the vulva of the person. The garment also provides at least one extensible member for positioning and securing the radiotherapeutic appliance such that the appliance is maintained in position and secured against movement during the radiation therapy.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: March 22, 1994
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventor: Donna M. Miller
  • Patent number: 5279600
    Abstract: The present invention provides a closed, fluid-modulating receiving system for the conveyance, modulation, and collection of fluid matter from its source. The receiving system may be employed under both in vivo and inanimate use conditions for the collection and disposal of fluids which may be infectious, hazardous, or toxic in and of themselves.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: January 18, 1994
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventor: John D. Hogan
  • Patent number: 5275584
    Abstract: The present invention provides a closed, fluid-modulating receiving system for the conveyance, modulation and collection of fluid matter from its source. The receiving system may be employed under both in vivo and inanimate use conditions for the collection and disposal of fluids which may be infectious, hazardous, or toxic in and of themselves.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: January 4, 1994
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventor: John D. Hogan
  • Patent number: 5274852
    Abstract: The present invention provides a one-piece, open-seam garment which encompasses the head, covers and conforms to the body and limbs of the wearer, and provides on-demand access to one portion of the covered body and limbs without uncovering the remainder of the body and legs. When worn, the garment provides privacy and protection for the person unlike the conventionally used johnnies and hospital gowns conventionally worn during physical examination or medical treatment in the physician's office or clinic.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: January 4, 1994
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventor: John D. Hogan
  • Patent number: 5273992
    Abstract: The present invention provides a chemical class of active compounds to be used as efficacious drugs in the treatment of sickle cell disease. The active compounds include imidazole derivatives, nitroimidazole derivatives, and triazole derivatives. These compounds are to be administered by any preferred route of administration including oral, intramuscular, intravenous, and any other parenteral route. If desired, these drugs may also be administered transmucosally, or subcutaneously, or using a dermal patch on the skin. In addition, the methodology is effective for both long term and short term therapy; may be employed prophylactically and/or therapeutically; and may be used in emergency, acute crisis clinical situations.
    Type: Grant
    Filed: November 2, 1992
    Date of Patent: December 28, 1993
    Assignee: Beth Israel Hospital Assoc. Inc.
    Inventors: Carlo Brugnara, Seth L. Alper
  • Patent number: 5139493
    Abstract: The present invention provides a closed, fluid-modulating receiving system for the conveyance, modulation, and collection of fluid matter from its source. The receiving system may be employed under both in vivo and inanimate use conditions for the collection and disposal of fluids which may be infectious, hazardous, or toxic in and of themselves.
    Type: Grant
    Filed: February 28, 1991
    Date of Patent: August 18, 1992
    Assignee: Beth Israel Hospital Assoc., Inc.
    Inventor: John D. Hogan
  • Patent number: 5135792
    Abstract: A disposable, self-enveloping and self-containing on-demand superabsorbent composite is provided which is easily transportable, durable, and can be prepared in both sterile and non-sterile formats. The disposable composite provides a fluid absorbing capacity via fibers able to absorb not less than 15 times their own weight in fluid and preferably are able to absorb at least 50 times their own weight in fluid and other liquid wastes. The composite can be prepared in various formats and styles for use in both hospitals, ambulances, emergency medical personnel, and by morticians and funeral directors as well.
    Type: Grant
    Filed: May 25, 1990
    Date of Patent: August 4, 1992
    Assignee: Beth Israel Hospital Assoc., Inc.
    Inventor: John D. Hogan
  • Patent number: 5054290
    Abstract: A portable and disposable, superabsorbent carrying container is provided which allows the user to obtain refrigeration on-demand for its contents. The container has a superabsorbent fibrous lining which absorbs not less than 15 times its own weight of fluids. In addition, the carrying container is able to provide refrigeration for the contents held within the internal volume of the container without the need for large mechanical refrigeration units or the use of previously frozen ice packs and the like.
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: October 8, 1991
    Assignee: Beth Israel Hospital Assoc.
    Inventor: John D. Hogan
  • Patent number: 5031634
    Abstract: A unique adjustable biopsy needle-guide device is provided which allows it to be inserted accurately at a selected anatomic site; to be secured in an engaged position; to be disengaged on-demand into a moveable form; and to be repositioned at will. The guide device comprises a cannula with multiple wires and sliding member elements as a preassembled unit which can be sterilized and conveniently stored until required for use by the physician. The needle-guide serves as a guide-post for the surgeon to remove small or deep seated lesions or for precise placement of biopsy needles at the target site.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: July 16, 1991
    Assignee: Beth Israel Hospital Assoc., Inc.
    Inventor: Morris Simon