Patents Assigned to Beth Israel Medical Center, Inc.
  • In-vitro T-lymphopoiesis system
    Patent number: 6004812
    Abstract: The present invention provides an in vitro T-lymphopoiesis system in which a population of T-cells is produced from precursor cells expressing CD34. The T-lymphopoiesis system of the present invention produces a population of T-cells of which approximately 17-74% express CD2, approximately 1.5-34% express CD3, and approximately 16-61% express CD4, and approximately 0-15% express CD8. A method of producing such a population of T-cells in vitro, as well as various compositions including T-cells of the present invention, are also provided.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: December 21, 1999
    Assignee: Beth Israel Medical Center, Inc.
    Inventors: David T. Scadden, Andrew Freedman