Abstract: A developmental, educational and entertainment system has a main module comprising a display, a computer or an interactive communication device or combination thereof, in which interactive applications are installed. A first remote control device controls the applications in the main module, and a second remote control device interacts with the applications in the main module. A remote control device suitable for use by infants comprises a button panel with 3 to 10 large buttons, that are removable so that buttons with various symbols can be inserted into the button panel, depending on the application, and optionally, the complete panel with the buttons is removable and interchangeable with other panels of buttons.