Abstract: Provided are a curcumin nanoparticle complex having a modified particle surface and a method for preparing same. A curcumin nanoparticle complex includes curcumin and phospholipids and has a particle size of less than 1000 nm. A first coating layer containing a cationic material and/or a second coating layer containing an anionic material can be further added.
Type:
Application
Filed:
September 1, 2023
Publication date:
February 29, 2024
Applicant:
BINOTEC CO., LTD.
Inventors:
Gi Hyun Jang, Chang Hwan Seok, Ji Won Shin, Yun Geum Sang Gwak, Yu Mi Kim
Abstract: Provided are a novel Lactiplantibacillus plantarum BNT_G401 strain and uses thereof. A method for manufacturing a ?-aminobutyric acid (GABA) containing fermented product includes (a) dissolving in water a Curcuma longa L. extract having a solid content of 0.5 to 10%; monosodium glutamate (MSG); a carbon source; and a nitrogen source, and sterilizing the same to manufacture a medium composition; (b) inoculating the medium composition with a Lactiplantibacillus plantarum strain; and (c) fermenting the medium composition in which the strain is inoculated to manufacture a GABA containing fermented product.
Type:
Application
Filed:
September 1, 2023
Publication date:
December 21, 2023
Applicant:
BINOTEC CO., LTD.
Inventors:
Yu Mi Kim, Gi Hyun Jang, Chang Hwan Seok, Ji Won Shin, Yun Geum Sang Gwak
Abstract: The present invention relates to a particulate nano-lipid carrier for the encapsulation of a bioactive material, and a method for producing same, and more specifically, to a particulate nano-lipid carrier having excellent nanoparticle stability and improved encapsulation of water-soluble drugs. A nano-lipid carrier according to the present invention has significantly improved bioactive material stability and encapsulation efficiency compared to conventional carriers, and it is anticipated that the nano-lipid carrier according to the present invention will be immediately commercializable as a raw material for cosmetics by means of a hair follicle targeting production method suitable for mass production.
Abstract: Provided is a method of preparing a bioactive substance-encapsulatedethosome, the method including: preparing an aqueous solution of a bioactive substance,preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.
Abstract: Provided is a method of preparing a bioactive substance-encapsulated ethosome, the method including: preparing an aqueous solution of a bioactive substance, preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.
Abstract: The present invention relates to a particulate nano-lipid carrier for the encapsulation of a bioactive material, and a method for producing same, and more specifically, to a particulate nano-lipid carrier having excellent nanoparticle stability and improved encapsulation of water-soluble drugs. A nano-lipid carrier according to the present invention has significantly improved bioactive material stability and encapsulation efficiency compared to conventional carriers, and it is anticipated that the nano-lipid carrier according to the present invention will be immediately commercializable as a raw material for cosmetics by means of a hair follicle targeting production method suitable for mass production.
Abstract: Provided is a method of preparing a bioactive substance-encapsulated ethosome, the method including: preparing an aqueous solution of a bioactive substance, preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.