Abstract: A spore-forming Bacillus species, and more particularly, a Bacillus subtilis strain identified as MB40 is provided. Compositions comprising the MB40 strain, methods of making products comprising the same, and methods of using the same are also provided.
Type:
Grant
Filed:
October 14, 2019
Date of Patent:
September 29, 2020
Assignee:
BIO-CAT, INC.
Inventors:
Christopher S. Penet, Sebhat Gebrechristos, Caroline Helen Best, Deborah S. Winetzky, Robert Daniel Little, Jr., Jessica Spears, Christopher Schuler
Abstract: A spore-forming Bacillus species, and more particularly, a Bacillus subtilis strain identified as MB40 is provided. Compositions comprising the MB40 strain, methods of making products comprising the same, and methods of using the same are also provided.
Type:
Grant
Filed:
October 2, 2017
Date of Patent:
December 3, 2019
Assignee:
BIO-CAT, INC.
Inventors:
Christopher S. Penet, Sebhat Gebrechristos, Caroline Helen Best, Deborah S. Winetzky, Robert Daniel Little, Jr., Jessica Spears, Christopher Schuler
Abstract: The invention relates to methods and compositions for reducing serum levels of triacylglycerides in human subjects. In particular, the invention relates to the oral administration of an effective amount of a fungal lipase formulation, to a human subject having borderline-high or high serum levels of triacylglycerides, for a time period sufficient to reduce serum triacylglyceride levels.
Type:
Grant
Filed:
September 18, 2012
Date of Patent:
January 31, 2017
Assignee:
BIO-CAT, INC.
Inventors:
Christopher Schuler, Edward Schuler, Christopher S. Penet, Kelly Gregory, K. Gregory Moore
Abstract: The invention relates to methods and compositions for reducing serum levels of triacylglycerides in human subjects. In particular, the invention relates to the oral administration of an effective amount of a fungal lipase formulation, to a human subject having borderline-high or high serum levels of triacylglycerides, for a time period sufficient to reduce serum triacylglyceride levels.
Type:
Application
Filed:
September 18, 2012
Publication date:
October 2, 2014
Applicant:
BIO-CAT, INC.
Inventors:
Christopher Schuler, Edward Schuler, Christopher S. Penet, Kelly Gregory, Gregory Moore
Abstract: The invention relates to methods and compositions for reducing serum levels of triacylglycerides in human subjects. In particular, the invention relates to the oral administration of an effective amount of a fungal lipase formulation, to a human subject having borderline-high or high serum levels of triacylglycerides, for a time period sufficient to reduce serum triacylglyceride levels.
Type:
Grant
Filed:
September 23, 2011
Date of Patent:
September 18, 2012
Assignee:
Bio-Cat, Inc.
Inventors:
Christopher Schuler, Edward Schuler, Christopher S. Penet, Gregory Moore, Kelly Gregory
Abstract: The invention provides compositions and methods for treating pancreatic enzyme insufficiency, such as the pancreatic enzyme insufficiency associated with cystic fibrosis. The invention also provides compositions comprising lipase from Candida cylindracea, alone or in combination with amylase or amyloglucosidase, protease and/or lactase. Furthermore, the invention discloses methods for treating pancreatic enzyme insufficiency comprising administering compositions to patients in need thereof.