Abstract: A mass spectrometry method includes a step of atomizing liquid including a sample using an ultrasonic transducer; a step of transferring the atomized liquid; a step of generating ions from the transferred liquid using a DART ion source; and a step of analyzing a mass spectrometry by introducing the generated ions into a mass spectrometer.
Type:
Grant
Filed:
April 14, 2014
Date of Patent:
March 14, 2017
Assignees:
SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.
Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.
Type:
Grant
Filed:
August 30, 2012
Date of Patent:
July 21, 2015
Assignees:
SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.
Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.
Type:
Grant
Filed:
December 26, 2011
Date of Patent:
January 6, 2015
Assignees:
Shiseido Company, Ltd., Bio Chromato, Inc.
Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.
Type:
Application
Filed:
August 30, 2012
Publication date:
July 3, 2014
Applicant:
SHISEIDO COMPANY, LTD., Tokyo, Japan and Bio Chromato, Inc.,
Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.
Type:
Application
Filed:
December 26, 2011
Publication date:
November 14, 2013
Applicants:
Bio Chromato, Inc., SHISEIDO COMPANY, LTD.
Abstract: A mass spectrometry method of the present invention is a method for conducting mass spectrometry in such a manner that an ion that is produced from a sample is introduced into a mass spectrometer by using DART or DESI, wherein the mass spectrometer has an ion introduction part for introducing the ion thereinto and the ion introduction part is heated at a predetermined timing.
Type:
Application
Filed:
December 26, 2011
Publication date:
October 31, 2013
Applicants:
Bio Chromato, Inc., SHISEIDO COMPANY, LTD.