Abstract: The present invention relates to Nelumbo nucifera callus having an increased content of gallic acid or an extract thereof and to a method for preparing the same. The Nelumbo nucifera callus extract according to the present invention has an excellent whitening effect by containing a large amount of gallic acid, and thus can be advantageously used as a cosmetic composition.
Type:
Grant
Filed:
March 30, 2017
Date of Patent:
March 16, 2021
Assignees:
Celltrion Inc., BIO-FD&C Co., Ltd.
Inventors:
Yeon Sook Kim, Jung Yeon Kim, Jae Hun Kim, Hyeong Mi Kim, Jung Soo Bae, Jung Yun Kim, Ju Yeon Kim, Joo Hyuck Lim, Seung Ki Lee, Sung Ho Moon, Shin Jae Chang, Sang Hyun Moh, Jeong Hun Lee, Hyo Hyun Seo, Ji Hong Moh, Soo Yun Kim, Jeong Gon Park
Abstract: There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.
Abstract: A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.
Type:
Grant
Filed:
December 28, 2011
Date of Patent:
March 12, 2019
Assignees:
KAMEDIS LTD., BIO-FD&C CO. LTD.
Inventors:
Sharon Rozenblat, DaiHyun Jung, SangHyun Moh, SuJung Kim, JungHun Lee
Abstract: There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.
Abstract: There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.
Abstract: Disclosed are peptide derivatives, wherein glutathione-like peptides are connected to benzoic acid derivatives, and a cosmetic composition comprising the same. The peptide derivatives have excellent tyrosinase inhibition and anti-oxidative activities to show excellent skin whitening effect, biocompatibility without skin stimulation, and stability during long-term storage. Therefore, they can be effectively used for a cosmetic composition for skin whitening.
Type:
Grant
Filed:
December 23, 2009
Date of Patent:
May 7, 2013
Assignee:
Bio-FD&C Co., Ltd
Inventors:
Dai Hyun Jung, Sang Hyun Moh, Jung Hun Lee, Su Jung Kim, Hyung Sik Kim, Hyo Hyun Seo, Yeon Ja Bae
Abstract: The present invention relates to peptide derivatives, wherein glutathione-like peptides are connected to benzoic acid derivatives, and a cosmetic composition comprising the same. The peptide derivatives according to the present invention have excellent tyrosinase inhibition and anti-oxidative activities to show excellent skin whitening effect, biocompatibility without skin stimulation, and stability during long-term storage. Therefore, they can be effectively used for a cosmetic composition for skin whitening.
Type:
Application
Filed:
December 23, 2009
Publication date:
October 14, 2010
Applicant:
BIO-FD&C CO., LTD.
Inventors:
Dai Hyun JUNG, Sang Hyun MOH, Jung Hun LEE, Su Jung KIM, Hyung Sik KIM, Hyo Hyun SEO, Yeon Ja BAE