Abstract: Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.
Type:
Grant
Filed:
January 13, 2005
Date of Patent:
March 30, 2010
Assignee:
Biolab Ltd
Inventors:
Elimelech Rochlin, Jean Hildesheim, Alisa Berlin