Patents Assigned to Bio-Medical Co., Ltd.
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Patent number: 11022558Abstract: The present invention discloses a coagulation analyzer and a coagulation analysis method which relate to the technical field of medical instruments. The coagulation analyzer includes an optical coagulation analysis module, a sample interference analysis module, a magnetic coagulation analysis module, and a test transfer module. The coagulation analyzer uses the sample interference analysis module to determine whether an interferent in the sample has effect on the coagulation test result of the optical coagulation analysis module. If the interferent in the sample has no effect on the coagulation test result, the optical coagulation analysis module is used to perform the coagulation analysis and report the test result. If the interferent in the sample has effect on the coagulation test result, the test transfer module is used to transfer the test to the magnetic coagulation analysis module to perform the coagulation analysis and report the test result.Type: GrantFiled: May 30, 2018Date of Patent: June 1, 2021Assignee: SHENZHEN THISTORY BIO-MEDICAL CO., LTDInventor: Lihua Zhang
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Publication number: 20190033221Abstract: The present invention discloses a coagulation analyzer and a coagulation analysis method which relate to the technical field of medical instruments. The coagulation analyzer includes an optical coagulation analysis module, a sample interference analysis module, a magnetic coagulation analysis module, and a test transfer module. The coagulation analyzer uses the sample interference analysis module to determine whether an interferent in the sample has effect on the coagulation test result of the optical coagulation analysis module. If the interferent in the sample has no effect on the coagulation test result, the optical coagulation analysis module is used to perform the coagulation analysis and report the test result. If the interferent in the sample has effect on the coagulation test result, the test transfer module is used to transfer the test to the magnetic coagulation analysis module to perform the coagulation analysis and report the test result.Type: ApplicationFiled: May 30, 2018Publication date: January 31, 2019Applicant: SHENZHEN THISTORY BIO-MEDICAL CO.,LTDInventor: Lihua ZHANG
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Patent number: 10065990Abstract: The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.Type: GrantFiled: September 2, 2014Date of Patent: September 4, 2018Assignee: HANGZHOU GUANYU BIO-MEDICAL CO., LTD.Inventors: Sheng Jiang, Zhiyi Yao, Yiwu Yao, Yatao Qiu, Changyin Lu, Kun Su, Xiaoming Yao
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Patent number: 9999645Abstract: A method of making longan seed extract is provided with choosing an extraction solvent; heating the extraction solvent to a first predetermined temperature; adding pulverized longan seed to the extraction solvent to prepare a solution; maintaining the solution at a second temperature for a predetermined period of time to obtain an extracted substance; filtering the extracted substance; and drying and cooling the filtered extracted substance to produce an extract.Type: GrantFiled: July 9, 2014Date of Patent: June 19, 2018Assignee: JOBEN BIO-MEDICAL CO., LTD.Inventors: Huang-Chung Tseng, Chien-Wei Hou
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Patent number: 9744205Abstract: The present invention provides a method for treating breast cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating breast cancer.Type: GrantFiled: February 1, 2012Date of Patent: August 29, 2017Assignee: JOBEN BIO-MEDICAL CO., LTD.Inventors: Wenchang Chiang, Yueh-Hsiung Kuo, Yun-Lian Lin, Cheng-Pei Chung
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Publication number: 20160280736Abstract: The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.Type: ApplicationFiled: September 2, 2014Publication date: September 29, 2016Applicant: HANGZHOU GUANYU BIO-MEDICAL CO., LTD.Inventors: Sheng Jiang, Zhiyi Yao, Yiwu Yao, Yatao Qiu, Changyin Lu, Kun Su, Xiaoming Yao
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Patent number: 9308233Abstract: The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1?, interleukin-1?, interleukin-6, tumor necrosis factor (TNF)-?, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).Type: GrantFiled: February 3, 2015Date of Patent: April 12, 2016Assignee: JOBEN BIO-MEDICAL CO., LTD.Inventors: Huang-Chung Tseng, Giao-Zhi Huang, Tung-An Chia
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Patent number: 9259451Abstract: The present invention provides use of alcohol extract of longan seeds for manufacturing a drug for treating kidney tissue dysfunction. Preferably, an ethyl acetate sub-fraction of the alcohol extract of longan seeds has a better effect in treating kidney tissue dysfunction.Type: GrantFiled: March 18, 2013Date of Patent: February 16, 2016Assignee: JOBEN BIO-MEDICAL CO., LTD.Inventors: Huang-Chung Tseng, Yi-Ting Hsiao, You-Zhong Zhan, Chun-Yi Yen, Jian-Sheng Lin
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Patent number: 8986754Abstract: The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1?, interleukin-1?, interleukin-6, tumor necrosis factor (TNF)-?, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).Type: GrantFiled: November 12, 2014Date of Patent: March 24, 2015Assignee: Joben Bio-Medical Co., Ltd.Inventors: Huang-Chung Tseng, Giao-Zhi Huang, Tung-An Chia
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Patent number: 8945638Abstract: The present invention provides a method for treating gastric ulcer and/or stomach cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating gastric ulcer and/or stomach cancer.Type: GrantFiled: November 25, 2011Date of Patent: February 3, 2015Assignee: Joben Bio-Medical Co., Ltd.Inventors: Wenchang Chiang, Yueh-Hsiung Kuo, Yun-Lian Lin, Cheng-Pei Chung
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Patent number: 8911800Abstract: The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1?, interleukin-1?, interleukin-6, tumor necrosis factor (TNF)-?, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).Type: GrantFiled: March 15, 2013Date of Patent: December 16, 2014Assignee: Joben Bio-Medical Co., Ltd.Inventors: Huang-Chung Tseng, Giao-Zhi Huang, Tung-An Chia
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Publication number: 20140093597Abstract: The present invention provides use of alcohol extract of longan seeds for manufacturing a drug for treating kidney tissue dysfunction. Preferably, an ethyl acetate sub-fraction of the alcohol extract of longan seeds has a better effect in treating kidney tissue dysfunction.Type: ApplicationFiled: March 18, 2013Publication date: April 3, 2014Applicant: JOBEN BIO-MEDICAL CO., LTD.Inventors: HUANG-CHUNG TSENG, YI-TING HSIAO, YOU-ZHONG ZHAN, CHUN-YI YEN, JIAN-SHENG LIN
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Patent number: 8686031Abstract: The present invention provides novel flavonoids extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the flavonoid and a method for treating inflammation in a subject, which method comprises administering to said subject an effective amount of the flavonoid and a pharmaceutically acceptable carrier or excipient.Type: GrantFiled: December 19, 2011Date of Patent: April 1, 2014Assignee: Joben Bio-Medical Co., Ltd.Inventors: Wenchang Chiang, Yun-Lian Lin, Cheng-Pei Chung, Hong-Jhang Chen
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Patent number: 8648215Abstract: The present invention provides novel spiroenones extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the spiroenones and a method for treating breast cancer in a subject, which method comprises administering to said subject an effective amount of the spiroenone and a pharmaceutically acceptable carrier or excipient.Type: GrantFiled: February 1, 2012Date of Patent: February 11, 2014Assignee: Joben Bio-Medical Co., Ltd.Inventors: Wenchang Chiang, Yueh-Hsiung Kuo, Yun-Lian Lin, Cheng-Pei Chung
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Patent number: 8633238Abstract: The present invention provides novel lactams extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the lactams and a method for treating breast cancer in a subject, which method comprises administering to said subject an effective amount of the lactam and a pharmaceutically acceptable carrier or excipient.Type: GrantFiled: February 1, 2012Date of Patent: January 21, 2014Assignee: Joben Bio-Medical Co., Ltd.Inventors: Wenchang Chiang, Yueh-Hsiung Kuo, Yun-Lian Lin, Cheng-Pei Chung
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Patent number: 4678468Abstract: In a cardiovascular prosthesis, at least a part of blood contact surface of the prosthesis is formed by polymer composition comprising water soluble polymer such as heparin and crosslinked polysiloxane, at least a part of the water soluble polymer being entangled or intertwisted into polysiloxane networks.Type: GrantFiled: August 5, 1985Date of Patent: July 7, 1987Assignee: Bio-Medical Co., Ltd.Inventor: Toshiki Hiroyoshi