Patents Assigned to BIO-ON S.P.A.
  • Patent number: 11832644
    Abstract: A process for producing a filter element suitable for use in smoking articles may include: embedding a bundle of cellulose acetate fibers with an aqueous suspension of polyhydroxyalkanoate (PHA) to obtain a wet bundle of the cellulose acetate fibers covered by the aqueous suspension of the PHA; shaping the wet bundle in a form of a continuous elongated element; heating the continuous elongated element to temperature greater than or equal to 140° C. and less than or equal to 180° C. for time sufficient to melt the PHA and to evaporate water from the continuous elongated element; cooling the heated continuous elongated element to obtain crystallization of the PHA; and cutting the so-obtained continuous elongated element into segments of predetermined length.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: December 5, 2023
    Assignee: BIO-ON S.p.A.
    Inventors: Paolo Saettone, Ilaria Monaco, Thomas M. Holsen, Mohammad Arifur Rahman, Philip K. Hopke, Mauro Comes Franchini
  • Patent number: 11636986
    Abstract: A supercondenser includes at least two electrodes separated by at least one separator having a polyhydroxyalkanoate (PHA) and at least one electrolyte, and relative production process. The supercondenser is flexible, biodegradable, and biocompatible, and can be made with reduced manufacturing costs and can be integrated, for example, in electronic devices that must be used inside biological organisms.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: April 25, 2023
    Assignee: BIO-ON S.P.A.
    Inventors: Paolo Saettone, Mario Cifelli, Lorenzo Migliorini, Gianluca Generali, Tommaso Santaniello, Ilaria Monaco, Paolo Milani, Mauro Comes Franchini
  • Patent number: 11433007
    Abstract: Powdered composition comprising: (a) 100 parts by weight of at least one polyhydroxyalkanoate (PHA) in the form of particles having an average diameter (d50) from 1 ?m to 100 ?m, preferably from 5 ?m to 60 ?m; (b) from 0.1 to 10 parts by weight, preferably from 0.5 to 5 parts by weight, of at least one silicate or silica. The powdered composition, having a relatively low abrasivity index and high flowability, can be used in air-polishing without causing excessive abrasion of the enamel and of the root cementum and without causing sticking in the device. Furthermore, the presence of PHA, being a polymer characterized by high biodegradability, makes the powdered composition particularly suitable for use in the oral cavity.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: September 6, 2022
    Assignee: BIO-ON S.p.A.
    Inventors: Antonino Ferraro, Paolo Saettone, Mauro Comes Franchini
  • Patent number: 11306202
    Abstract: A composition including at least one polyhydroxyalkanoate (PHA) having saturated side chains dissolved in at least one aromatic solvent between 50 g/1 and 200 g/l and preferably between 80 g/l and 180 g/l. The at least one PHA has a weight-average molecular weight (Mw) not greater than 250,000 Da and preferably not greater than 150,000 Da. This composition is particularly suitable as a binder for coating products. The composition can be produced by mixing the PHA with the aromatic organic solvent and heating the mixture at a temperature close to the PHA melting temperature, maintaining the mixture under stirring until complete dissolution of the polymer. Alternatively, the composition can be produced by dissolution of the PHA in a non-aromatic organic solvent having low boiling temperature where the PHA is highly soluble, subsequent addition of the aromatic organic solvent and subsequent removal of the non-aromatic organic solvent by fractional distillation.
    Type: Grant
    Filed: November 22, 2018
    Date of Patent: April 19, 2022
    Assignee: BIO-ON S.P.A.
    Inventors: Olga Bortolini, Alessandro Massi, Dario Cristofaro, Simone Begotti
  • Patent number: 11173218
    Abstract: Biocompatible polymeric nanoparticles may include: a biocompatible polymer and/or functional metal nanostructures. The biocompatible polymer may be a polyhydroxyalkanoate (PHA). The functional metal nanostructures may include at least one noble metal, at least one magnetic metal oxide, or mixtures thereof. The biocompatible polymeric nanoparticles may have an average size less than or equal to 200 nanometers (nm).
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: November 16, 2021
    Assignee: BIO-ON S.P.A.
    Inventor: Mauro Comes Franchini
  • Patent number: 11021382
    Abstract: A method for bioremediation of waters contaminated with hydrocarbons may include: putting the contaminated waters in contact with at least one polyhydroxyalkanoate (PHA); and/or allowing microorganisms, present in the contaminated waters and capable of metabolizing the hydrocarbons, to develop and degrade the hydrocarbons under an aerobic condition.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: June 1, 2021
    Assignee: BIO-ON S.P.A.
    Inventors: Simone Cappello, Simone Begotti, Lucrezia Genovese
  • Publication number: 20200024172
    Abstract: A method for bioremediation of waters contaminated with hydrocarbons may include: putting the contaminated waters in contact with at least one polyhydroxyalkanoate (PHA); and/or allowing microorganisms, present in the contaminated waters and capable of metabolizing the hydrocarbons, to develop and degrade the hydrocarbons under an aerobic condition.
    Type: Application
    Filed: September 25, 2017
    Publication date: January 23, 2020
    Applicant: Bio-On S.p.A.
    Inventors: Simone CAPPELLO, Simone BEGOTTI, Lucrezia GENOVESE
  • Patent number: 9796988
    Abstract: A process for producing hydroxyalkanoate copolymers, which comprises: (i) pre-treating a sucrose-containing feedstock in an acidic solution; (ii) feeding the pre-treated feedstock into a bioreactor containing polyhydroxyalkanoate producing microbial cells; (iii) cultivating the polyhydroxyalkanoate producing microbial cells to form a cell mass containing the hydroxyalkanoate copolymers; (iv) recovering the hydroxyalkanoate copolymers from the cell mass. The pre-treating step has the main function of hydrolyzing sucrose into glucose and fructose, which in turn are converted into 4-ketovaleric acid to give a mixture of mono-saccharides and organic precursors for microbial synthesis of hydroxyalkanoate copolymers, and particularly of PHBVV ter-polymers. Complex and expensive purification processes of the substrates obtained from the pre-treating step are not needed. The solutions can be directly used as the feeding solutions for microbial PHA biosynthesis.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: October 24, 2017
    Assignee: BIO-ON S.p.A.
    Inventor: Jian Yu
  • Patent number: 9683076
    Abstract: A process for recovering and purifying polyhydroxyalkanoates from a cell culture may include: (a) acidifying the culture to obtain a pH value less than or equal to 6, and submitting the culture to a cell fractionation treatment using high-pressure homogenization at a temperature greater than or equal to 10° C. and less than or equal to 80° C. to obtain a suspension; (b) basifying the suspension to obtain a pH value greater than or equal to 8; (c) diluting the suspension and submitting the diluted PHA suspension to tangential filtration to obtain a concentrated suspension as retentate and an aqueous phase as permeate; (d) submitting the concentrated suspension to bleaching; (e) diluting the suspension after the bleaching and submitting the diluted bleached suspension to tangential filtration to obtain a concentrated bleached suspension as retentate and an aqueous phase as permeate; and/or (f) submitting the concentrated bleached suspension to drying.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: June 20, 2017
    Assignee: BIO-ON S.P.A.
    Inventor: Simone Begotti