Patents Assigned to Bio-Path Holdings, Inc.
  • P-ETHOXY NUCLEIC ACIDS FOR IGF-1R INHIBITION
    Publication number: 20220133775
    Abstract: Provided herein are methods of treating cancer or an autoimmune disease comprising administering a liposome that comprises neutral phospholipids and a P-ethoxy oligonucleotide that targets a IGF-1R-encoding polynucleotide.
    Type: Application
    Filed: November 18, 2021
    Publication date: May 5, 2022
    Applicants: Bio-Path Holdings, Inc., Thomas Jefferson University
    Inventors: Ana Ashizawa, Douglas Craig Hooper, David W. Andrews
  • P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION
    Publication number: 20210361695
    Abstract: Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.
    Type: Application
    Filed: December 18, 2020
    Publication date: November 25, 2021
    Applicant: Bio-Path Holdings, Inc.
    Inventor: Peter NIELSEN
  • P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION
    Publication number: 20200113928
    Abstract: Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.
    Type: Application
    Filed: May 30, 2019
    Publication date: April 16, 2020
    Applicant: Bio-Path Holdings, Inc.
    Inventor: Peter NIELSEN
  • P-ETHOXY NUCLEIC ACIDS FOR IGF-1R INHIBITION
    Publication number: 20200038429
    Abstract: Provided herein are methods of treating cancer or an autoimmune disease comprising administering a liposome that comprises neutral phospholipids and a P-ethoxy oligonucleotide that targets a IGF-1R-encoding polynucleotide.
    Type: Application
    Filed: April 19, 2018
    Publication date: February 6, 2020
    Applicants: Bio-Path Holdings, Inc., Thomas Jefferson University
    Inventors: Ana Ashizawa, Douglas Craig Hooper, David W. Andrews
  • P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION
    Publication number: 20180161360
    Abstract: Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.
    Type: Application
    Filed: July 21, 2017
    Publication date: June 14, 2018
    Applicant: Bio-Path Holdings, Inc.
    Inventor: Peter NIELSEN
  • P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION
    Publication number: 20170106010
    Abstract: Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 20, 2017
    Applicant: Bio-Path Holdings, Inc.
    Inventor: Peter NIELSEN