Patents Assigned to Bio Products Laboratory Limited
  • Process for the preparation of immunoglobulin G (IgG)
    Patent number: 11149079
    Abstract: The present invention is directed to processes for extracting IgG from an unused waste precipitate produced during normal plasma fractionation processes via a separate fractionation process, thereby increasing the overall yield of IgG from blood plasma.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: October 19, 2021
    Assignee: BIO PRODUCTS LABORATORY LIMITED
    Inventors: John More, Tara Dolan
  • Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
    Patent number: 9956272
    Abstract: Methods for preparing Factor X, activated Factor X, inactivated factor X and inactivated factor Xa, compositions comprising Factor X and Factor Xa, inactivated Factor X and inactivated Factor Xa and methods of medical treatment using Factor X, Factor Xa, activated Factor X and inactivated Factor Xa are disclosed. The preparation methods comprise a chromatography step using an immobilised metal ion affinity chromatography substrate.
    Type: Grant
    Filed: May 29, 2008
    Date of Patent: May 1, 2018
    Assignee: Bio Products Laboratory Limited
    Inventors: Joanne Lloyd, Peter Feldman
  • Method for the isolation of haptoglobin
    Patent number: 9145448
    Abstract: The invention provides a method for the isolation of haptoglobin from a sample comprising Cohn fraction V, wherein said method comprises anion exchange chromatography of said sample. The product may be further purified and/or subjected to one or more virus inactivation or reduction steps. The isolated haptoglobin may then be formulated for pharmaceutical use.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: September 29, 2015
    Assignee: BIO PRODUCTS LABORATORY LIMITED
    Inventors: Joan Dalton, Adrian Podmore, Peter Kumpalume
  • Method for the purification of alpha-1-antitrypsin
    Patent number: 8580931
    Abstract: The invention relates to methods for the isolation of AAT from solutions containing albumin and AAT using at least two separate metal chelate chromatography steps. The product may be further purified and/or subjected to one or more virus inactivation or reduction steps. The isolated AAT may then be formulated for pharmaceutical use.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: November 12, 2013
    Assignee: Bio Products Laboratory Limited
    Inventors: Peter Kumpalume, Adrian Podmore, Joan Dalton
  • Process for producing a virus-inactivated thrombin preparation
    Patent number: 8435779
    Abstract: The present invention relates to processes for the preparation of virus inactivated thrombin, and to the products prepared by these processes.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: May 7, 2013
    Assignee: Bio Products Laboratory Limited
    Inventors: Caroline Connolly, Christopher Hardway, David Evans, Peter Feldman
  • Treating protein-containing liquids
    Patent number: 8226776
    Abstract: Abnormal infective prion proteins are removed from liquids containing biologically active substances, particularly blood products, by filtration using a depth filter formed of a matrix comprising solid particles of porous material and having a pore size less than 6 microns. Preferably the filter is free of cationic or anionic charged material.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: July 24, 2012
    Assignee: Bio Products Laboratory Limited
    Inventors: Anne Gillian Welch, Peter Reynolds Foster