Abstract: The present invention relates to solid supports for control nucleic acids. The present invention also relates to methods for the manufacture thereof, and methods of use thereof.

Abstract: Apparatus and washing and extracting head for an apparatus designed to wash microplates. The head is mobile above the microplate(s) in treating position and comprises an alignment of dispensing needles or tubes and suction needles or tubes associated in pairs, the number of the two types of needle pairs being equal to the number of wells per column or per row and the spacing between two adjacent pairs being equal to the spacing between two adjacent wells of the same column or row. The suction needles, and the parts of the consecutive suction and/or recovery circuit, have a passage cross sectional diameter not less than the largest transverse dimension of the sample supports present in the wells and the head comprises or co-operates with elements retaining the microplate to be washed or preventing it from being lifted, at least during the suction extraction phase.

Abstract: The invention proposes a liquid phase chromatography module (1) comprising: a container (2) having an upper end (4) and a lower end (5) which are open and have complementary shapes; a chromatographic mixture (9) in the container (2); a filtering membrane (10) fixedly disposed at one end (5) of the container (2). The invention also proposes a chromatography column comprising a stack of said modules (1) fitted together.

Abstract: The invention relates to a method of immobilizing an affinity reagent or affinity reagents on a hydrophobic solid phase which can be used in biological assays for analyte detection. The invention relates more particularly to a method of immobilizing an affinity reagent on a hydrophobic solid phase functionalized by a carboxyl group, said method comprising a step for activation of said solid phase and a step for coupling of the affinity reagent to said solid phase, characterized in that the step for activation of said solid phase uses a combination of a carbodiimide and a phosphate buffer in the presence of a co-activator and in an acid medium, and in that the coupling step is performed in a basic medium. The invention further relates to the reactive complexes obtained by this method and to their use in immunoassay kits, hybridization kits or enzymatic assay kits.

Abstract: Synthetic peptides of the monomer type with 13 to 33 amino acids, in linear form or in a form cyclized by means of inter-cysteine disulphide bridges, have the general formula (I): ?-Z-TrpGlyCys-?-CysTyrThrSer-???(I) wherein ? is a biotinyl radical, a biocytinyl radical, a hydrogen atom, an acetyl (CH3CO—) radical, an aliphatic chain which may contain one or two thiol, an aldehyde functional group, or an amine functional group, Z represents peptide sequence -?1-Ser-?2-, -?1-Gln-?2-, or -?1-Asn-?2-, wherein -?1 represents a peptide sequence of 0 to 9 amino acids and -?2 represents a peptide sequence of 0 to 5 amino acids, ? is -Arg Gly Arg Leu Ile-(SEQ ID NO: 15), -Arg Gly Arg Leu Val-(SEQ ID NO: 16), -Arg Gly Lys Leu Ile- (SEQ ID NO: 17), -Arg Gly Lys Leu Val-(SEQ ID NO: 18), -Lys Gly Arg Leu Ile-(SEQ ID NO: 19), or -Lys Gly Arg Leu Val-(SEQ ID NO: 20), ?, attached to the —CO— group of serine, is a hydroxyl (—OH) radical, an amino (—NH2) radical, an alkoxy radical having 1 to 6 carbon atoms, a peptide sequen

Abstract: Device for mounting an elongated element with axial clamping, includes a body forming a support base whereon are fixed a stop part including a first support element for one end of the elongated element and a retaining part, the parts being axially separated, a removable support block comprising a through passage for receiving the elongated element and capable of being wedged between the retaining part and stop part, and a mobile part including a second support element for the other end of the elongated element, the mobile part is secured in articulation to two link rods mounted at their opposite ends, potentially rotatable, on two eccentrics mounted potentially rotatable on the body and rigidly assembled to a pivoting cover provided with a member or zone for gripping or maneuvering, the cover or lid substantially covering the assembly of the parts and the elements when it is folded down.

Abstract: The invention relates to synthetic biepitope compounds which can be used as standards in immunoassays, for the assay of troponin I, method for preparing them, compositions and kits containing such compounds as well as the immunoassay methods using such compounds.

Abstract: The invention relates to a device for collecting a soft biological sample and to a method for using the same. The device comprises a hollow cylindrical body (10) with two openings (10A, 10B), one at each end, wherein a piston (12) with a rod (14) is inserted via a first end and the piston-and-rod assembly can be displaced back and forth inside the hollow cylindrically (10), the opening in the second end (10B) of the hollow cylindrical body (10) has a slicing edge (10B) and this second end carries a cutting wire arranged across its opening.

Abstract: The present invention relates to stabilized compositions of troponin capable of serving as standard and/or control in immunoassays intended for assaying cardiac and/or skeletal troponin(s) in the blood serum or blood plasma of humans or animals. These stabilized compositions comprise, in aqueous solution, troponin I, troponin T and troponin C in the form of an I-T-C ternary complex.