Patents Assigned to BIO SOLUTION CO., LTD.
  • Artificial cartilage containing chondrocytes obtained from costal cartilage and preparation process thereof
    Patent number: 10583157
    Abstract: The present invention relates to an artificial cartilage containing mesenchymal stem cell (MSC)-like dedifferentiated cells obtained by passage culturing costal chondrocytes, and a preparation process thereof.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: March 10, 2020
    Assignees: BIO SOLUTION CO., LTD., KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY
    Inventors: Young Sook Son, Jung Sun Lee, Eun Kyung Lee, Jin Yeon Lee
  • Preparation method for therapeutic agent of bead-type chondrocyte
    Patent number: 9956251
    Abstract: The present invention relates to a preparation method for a therapeutic agent of a bead-type chondrocyte and, more specifically, to: a preparation method for a therapeutic agent of a bead-type chondrocyte without a support, comprising the steps of: a) dispensing chondrocytes and/or cells having chondrogenic differentiation capability in a 96-well deep well plate having a V-shaped bottom; b) centrifuging the plate; c) three-dimensionally culturing the plate in an incubator; and d) recovering pellets from each well, thereby being capable of easily and stably preparing cartilage tissues of a uniform quality, in large quantities; and a therapeutic agent of a bead-type chondrocyte without a support, prepared by the method, having effectiveness to repair damage by simply being implanted into cartilage damage by injection.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: May 1, 2018
    Assignee: BIO SOLUTION CO., LTD.
    Inventors: Jung Sun Lee, Jin Yeon Lee, Byung Chul Chae, Young Sook Son, Song Sun Chang
  • ARTIFICIAL CARTILAGE CONTAINING CHONDROCYTES OBTAINED FROM COSTAL CARTILAGE AND PREPARATION PROCESS THEREOF
    Publication number: 20170274018
    Abstract: The present invention relates to an artificial cartilage containing mesenchymal stem cell (MSC)-like dedifferentiated cells obtained by passage culturing costal chondrocytes, and a preparation process thereof.
    Type: Application
    Filed: June 12, 2017
    Publication date: September 28, 2017
    Applicants: BIO SOLUTION CO., LTD., KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY
    Inventors: Young Sook SON, Jung Sun LEE, Eun Kyung LEE, Jin Yeon LEE
  • Artificial cartilage containing chondrocytes obtained from costal cartilage and preparation process thereof
    Patent number: 9694034
    Abstract: The present invention relates to an artificial cartilage containing mesenchymal stem cell (MSC)-like dedifferentiated cells obtained by passage culturing costal chondrocytes, and a preparation process thereof.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: July 4, 2017
    Assignees: BIO SOLUTION CO., LTD., KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY
    Inventors: Young Sook Son, Jung Sun Lee, Eun Kyung Lee, Jin Yeon Lee
  • Method of predicting protein-ligand docking structure based on quantum mechanical scoring
    Patent number: 8886505
    Abstract: Provided is a protein-ligand docking prediction method based on quantum mechanical scoring. The method includes evaluating a protein-ligand docking structure by using a molecular mechanical energy-based scoring function and reevaluating the protein-ligand docking structure by using a rescoring function obtained by combining a quantum mechanical factor with the molecular mechanical energy-based scoring function. In accordance with the method using the quantum mechanical scoring, it is possible to more accurately carry out modeling than conventional force field-based methods.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: November 11, 2014
    Assignee: Quantum Bio Solutions Co., Ltd.
    Inventor: Art Eunsung Cho