Patents Assigned to Bio-Sphere Technology
  • Method for inducing a systemic immune response to an HIV antigen
    Patent number: 6207185
    Abstract: A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: March 27, 2001
    Assignee: Bio-Sphere Technology
    Inventors: Jackie R. See, Darryl M. See