Abstract: Expression profiling of FFPE sample areas smaller than 2 mm2 with single-cell sensitivity, correlated with tissue microenvironment morphology and neoplastic grade. An automated digital molecular pathology instrument for integrated imaging, immunohistochemical assessment, and processing samples for sequence detection assays. Software for instrument and sample control and analysis.
Type:
Grant
Filed:
April 16, 2018
Date of Patent:
August 17, 2021
Assignee:
BioSpyder Technologies, Inc.
Inventors:
Elliot Imler, Milos Babic, Bruce Seligmann
Abstract: Methods for detecting nucleic acid sequences, where attenuator oligonucleotides are provided to reduce the number of detection products resulting from highly abundant sequences.
Type:
Grant
Filed:
September 8, 2014
Date of Patent:
May 1, 2018
Assignee:
BIOSPYDER TECHNOLOGIES, INC.
Inventors:
Joanne M. Yeakley, Bruce Seligmann, Joel McComb