Abstract: The present invention relates to cells which have improved receptivity to viruses which are capable of infecting them. Receptivity to such viruses is improved by selecting cells from a population which express the receptor(s) that enable a virus to attach to the cell and gain entry into it. Any combination of viruses and host cell lines can be used. In a preferred embodiment, the present invention relates to improving receptivity or infectivity of a cell line which can be infected with an immunodeficiency virus, such as HIV-1.
Type:
Grant
Filed:
April 27, 1999
Date of Patent:
October 8, 2002
Assignee:
Bio-Tech Imaging, INC
Inventors:
Robert A. Hallowitz, Susan Young, Chester King