Patents Assigned to Bio-Technical Resources
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Patent number: 7842497Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: November 30, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7838279Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: November 23, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7732161Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: June 8, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7718417Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: May 18, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Publication number: 20090017520Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucosamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.Type: ApplicationFiled: June 22, 2007Publication date: January 15, 2009Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical ResourcesInventors: Alan Berry, Richard P. Burlingame, James R. Millis
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Publication number: 20060094085Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucsamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.Type: ApplicationFiled: October 5, 2005Publication date: May 4, 2006Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical ResourcesInventors: Alan Berry, Richard Burlingame, James Millis
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Publication number: 20030125573Abstract: The invention provides a method of producing &agr;-tocopherol and &agr;-tocopheryl esters. The method comprises using a biological system to produce farnesol or geranylgeraniol. Then, the farnesol or geranylgernaiol is chemically converted into &agr;-tocopherol or an &agr;-tocopheryl ester.Type: ApplicationFiled: July 9, 2001Publication date: July 3, 2003Applicant: DCV, Inc., d/b/a Bio-Technical ResourcesInventors: James R. Millis, Gabriel G. Saucy, Julie Maurina-Brunker, Thomas W. McMullin
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Publication number: 20030092144Abstract: The invention provides a biological method of producing farnesol or geranylgeraniol.Type: ApplicationFiled: July 20, 2001Publication date: May 15, 2003Applicant: DCV, Inc. d/b/a Bio-Technical Resources.Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 5998329Abstract: The invention is directed to an unsintered spherical adsorbent particle composition having high mechanical strength and controlled pore size distribution, comprising finely divided silica hydrogel particles bonded together with a silica or metal oxide sol.Type: GrantFiled: June 30, 1997Date of Patent: December 7, 1999Assignee: Bio-Technical ResourcesInventors: Mahlon Robert Derolf, Leonard Harris Smiley, Reinhard Herbert Witt
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Patent number: 5902579Abstract: Natamycin biomass comprising 5-60% natamycin, most preferably 25-60% natamycin, and methods for forming the biomass, are disclosed. The natamycin biomass can be mixed with compatible carrier to form a premix comprising 0.2-5% natamycin. The premlix may be mixed with animal feed to form an animal feed mixture comprising cracked grain and 1.1-110 ppm of natamycin.Type: GrantFiled: April 29, 1996Date of Patent: May 11, 1999Assignee: Bio-Technical ResourcesInventors: Michael Alan Eisenschink, James R. Millis, Phillip Terry Olson, Bruce Dexter King, Mary Ellen Rowland
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Patent number: 5900370Abstract: The present invention is directed to methods for the production of ascorbic acid by culturing organisms of the genus Prototheca and recovering ascorbic acid from the fermentation medium.Type: GrantFiled: June 7, 1995Date of Patent: May 4, 1999Assignee: Bio-Technical ResourcesInventor: Jeffrey Running
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Patent number: 5753180Abstract: A non-biocidal method for inhibiting microbially influenced corrosion of susceptible metal surfaces having an anaerobic biofilm containing active sulfate-reducing bacteria comprising contacting the biofilm with a liquid dispersion of anthraquinone compound.Type: GrantFiled: August 9, 1996Date of Patent: May 19, 1998Assignee: Bio-Technical ResourcesInventor: Edward Daniel Burger
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Patent number: 5728898Abstract: Process for making water-soluble hydroquinone salts by reacting an aqueous liquid solution of (a) a formamidinesulfinic acid and (b) an alkali metal or quaternary ammonium hydroxide in which is dispersed a (c) quinone and water-soluble hydroquinone salts made thereby.Type: GrantFiled: June 27, 1996Date of Patent: March 17, 1998Assignee: Bio-Technical Resources, L.P.Inventor: Mark Harry Krackov
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Patent number: 5648258Abstract: Anthraquinone compounds inhibit methane production by methanogenic bacteria in the rumen of ruminant animals, increasing production of volatile fatty acids and feed utilization efficiency. Preferred anthraquinones are unsubstituted anthraquinone, 1-aminoanthraquinone, 1-chloroanthraquinone, 2-chloroanthraquinone, 2-chloro-3-carboxyanthraquinone, 1-hydroxyanthraquinone, and 9,10-dihydroanthraquinone.Type: GrantFiled: July 24, 1995Date of Patent: July 15, 1997Assignee: Bio-Technical ResourcesInventor: James Martin Odom
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Patent number: 5612184Abstract: Devices for the detection of small quantities either of divalent inorganic mercury ion (Hg.sup.2+) or of both Hg.sup.2+ and monomethyl mercury in water are disclosed. These devices comprises a bioluminescence detecting means and a bioluminescent biosensory microorganism cells, that emit significant light only when exposed to either to Hg.sup.2+ or to Hg.sup.2+ or momomethyl mercury. Plasmid cassettes and host microorganisms containing such cassettes are also disclosed The plasmid cassettes comprises a lux gene operon complex from Xenorhabdus luminescens. The lux operon complex comprises luxC, luxD, luxA, luxB, and luxE genes but is free of (1) a promoter for the complex and (2) an inducible regulatory gene for the complex.Type: GrantFiled: June 6, 1995Date of Patent: March 18, 1997Assignee: Bio-Technical Resources L.P.Inventor: Reinhardt A. Rosson
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Patent number: 5591438Abstract: A process for the recovery of high purity natamycin from fermentaion broth by extraction with methanol is disclosed. In one embodiment the process comprises the steps:(1) adding methanol to a natamycin feed stream comprising at least 2 g/L of solid suspended natamycin to form an extraction medium, and maintaining the extraction medium at a temperature of 0.degree.-25.degree. C., preferably not over 15.degree. C.;(2) adjusting the pH of the extraction medium to 1.0 to 4.5 while maintaining the temperature at 0.degree.-25.degree. C. for 0.5 to 30 hours, but preferably not over 0.5 hours when the temperature is 15.degree.-25.degree. C.;(3) removing solids from the extraction medium to form an extraction liquor;(4) raising the pH of the extraction liquor to 6.0-9.0; and(5) recovering precipitated natamycin.Type: GrantFiled: May 3, 1994Date of Patent: January 7, 1997Assignee: Bio-Technical Resources L.P.Inventors: Phillip T. Olson, James R. Millis, Michael H. Reimer
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Patent number: 5571722Abstract: Devices for the detection of small quantities either of divalent inorganic mercury ion (Hg.sup.2+) or of both Hg.sup.2+ and monomethyl mercury in water are disclosed. These devices comprises a bioluminescence detecting means and a bioluminescent biosensory microorganism cells, that emit significant light only when exposed to either to Hg.sup.2+ or to Hg.sup.2+ or momomethyl mercury. Plasmid cassettes and host microorganisms containing such cassettes are also disclosed The plasmid cassettes comprises a lux gene operon complex from Xenorhabdus luminescens. The lux operon complex comprises luxC, luxD, luxA, luxB, and luxE genes but is free of (1) a promoter for the complex and (2) an inducible regulatory gene for the complex.Type: GrantFiled: August 23, 1993Date of Patent: November 5, 1996Assignee: Bio-Technical Resources L.P.Inventor: Reinhardt A. Rosson
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Patent number: 5521090Abstract: Microalgal biomass that comprises cells of Chlorella pyrenoidosa which contain greater than 2.0% by dry weight of L-ascorbic acid (Vitamin C), microorganisms and processes that form the biomass, and L-ascorbic acid enhanced animal feed compositions that contain the biomass are disclosed.Type: GrantFiled: February 10, 1994Date of Patent: May 28, 1996Assignee: Bio-Technical ResourcesInventors: James A. Doncheck, Ronald J. Huss, Jeffrey A. Running, Thomas J. Skatrud
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Patent number: 5500368Abstract: A method of inhibit sulfide production in a media containing sulfate-reducing bacteria is disclosed. The method comprises adding particles of a finely divided sulfide production-inhibiting anthraquinone to the medium. The particles have a particle size of 0.1 to 2.5 microns, preferably 2 to 0.1 microns.Type: GrantFiled: October 21, 1994Date of Patent: March 19, 1996Assignee: Bio-Technical ResourcesInventor: Robert E. Tatnall
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Patent number: 5470728Abstract: Cis-dihydrodiol compounds of the formula ##STR1## where n is 0 or 1 (preferably 0) are produced by the microbial oxidation of a diphenylaceylene compound of the formula ##STR2## using a mutant of a Pseudomonas bacteria at 25.degree. to 35.degree. C. and pH 6-8. The cis-dihydrodiol compound is in turn treated with an aqueous solution of a base to produce a corresponding 3-hydroxydiphenylacetylene compound or with an aqueous solution of an acid to produce a corresponding 2-hydroxyacetylene compound. The mutant strain is preferably Pseudomonas ATCC 55272.Type: GrantFiled: August 8, 1994Date of Patent: November 28, 1995Assignee: Bio-Technical ResourcesInventor: Alan D. Grund