Patents Assigned to BIO3 Research SRL
  • HMGB1 PROTEIN INHIBITORS AND/OR ANTAGONISTS FOR THE TREATMENT OF VASCULAR DISEASES
    Publication number: 20100297107
    Abstract: A method of treating vascular diseases by administering an antagonist molecule that inhibits the interaction between a protein of the HMG box family and a receptor for the protein of the HMG box family.
    Type: Application
    Filed: February 17, 2010
    Publication date: November 25, 2010
    Applicants: BIO3 RESEARCH SRL, MARCO E. BIANCHI
    Inventors: Marco E. BIANCHI, Tiziana Bonaldi, Paola Scaffidi, Susanne Mueller, Bernard Degryse
  • HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
    Patent number: 7754217
    Abstract: The use of HMG box-binding molecules and molecules having sequence homology with HMG box for the preparation of therapeutic agents for the treatment of vascular diseases is described.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: July 13, 2010
    Assignees: BIO3 Research SRL
    Inventors: Marco E. Bianchi, Tiziana Bonaldi, Paola Scaffidi, Susanne Mueller, Bernard Degryse
  • HMGB1 PROTEIN INHIBITORS AND/OR ANTAGONISTS FOR THE TREATMENT OF VASCULAR DISEASES
    Publication number: 20100172896
    Abstract: A method of inhibiting atherosclerosis by administering a molecule that binds a protein of the HMG box family. Also, a method of treating vascular diseases by administering an antagonist molecule to inhibit the interaction between a protein of the HMG box family and a receptor for the protein of the HMG box family.
    Type: Application
    Filed: February 17, 2010
    Publication date: July 8, 2010
    Applicants: BIO3 RESEARCH SRL
    Inventors: Marco E. Bianchi, Tiziana Bonaldi, Paola Scaffidi, Susanne Mueller, Bernard Degryse
  • Hmgb1 protein inhibitors for the regulation of smooth muscle cells and endothelial cells profileration
    Publication number: 20070141060
    Abstract: The use of molecules that modulate the action of HMGB1 protein (or molecules having sequence homology) for the preparation of therapeutic agents for the treatment of diseases to related to endothelial and smooth muscle cells proliferation; said proliferation can be due to endothelium damage, caused by surgical operation and manipulation made on or through blood vessels, including coronary and/or carotid angioplasty, angiographic surgery, and surgery using catheters.
    Type: Application
    Filed: January 26, 2005
    Publication date: June 21, 2007
    Applicants: BIO3 RESEARCH SRL
    Inventor: Marco Bianchi